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All Journal Jurnal Kedokteran Diponegoro STRADA Jurnal Ilmiah Kesehatan
Novi Kusumaningrum
Dept Of Dermatology And Venerology, Faculty Of Medicine Diponegoro University Semarang
Medicine & Pharmacology Nursing Public Health

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DIFFERENCES IN INTERLEUKIN-23 SERUM LEVELS TOWARDS THE SEVERITY OF ACNE VULGARIS IN WOMEN Wafi Banadzir Resya; Novi Kusumaningrum; Santoso Jaeri; Astika Widy Utomo
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30029

Abstract

Background: Acne vulgaris is a chronic inflammatory disease in the pilosebaceous gland of the skin which can cause depression and anxiety. IL-23 is a cytokine that is involved in autoimmune diseases, including acne vulgaris. IL-23 affects the differentiation process of Th17 which further produces IL-17, an important component in the pathogenesis of acne vulgaris. IL-17 plays a significant role in the grade of skin damage caused by the inflammation process.Objective: To find out differences in IL-23 serum levels and the grade of AV severity in women.Methods: An observational study with a cross-sectional design approach conducted from June until October 2020 in 15 women with AV aged 15-25 years old, not consuming anti-inflammatory drugs, antibiotics, retinoid group of drugs and free from other inflammatory diseases. Subjects were divided into three groups based on the AV severity grade: specifically mild (n=5), moderate (n=5) and severe (n=5). Subjects had venous blood taken for IL-23 serum content by the ELISA method. Data on IL-23 serum content in the three groups were tested using the One-Way ANOVA method to determine the differenceResults: Average age from the 3 groups was 21 (17-23 ) years old. The results showed that there is no significant difference in IL-23 rate from the 3 groups of AV severities (p=0,490).Conclusion: : There is no significant difference of IP-23 rate between the 3 groups of AV severites in women. 
Music Therapy in Post-Stroke Patient Anxiety Problems: Scoping Review Elisabeth Yunita Sofiana Mbau; Fitria Handayani; Novi Kusumaningrum
STRADA Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Institut Ilmu Kesehatan STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.525 KB) | DOI: 10.30994/sjik.v9i2.521

Abstract

This article uses the scoping review method, through a review of articles on music therapy interventions that have been used to reduce anxiety in post-stroke patients. Article searches are accessed through the database: CINAHL, MEDLINE, Academic search ultimate, science direct, and google scholar. Results: Music therapy can be applied to treat psychological problems such as anxiety in post-stroke patients. The results of the review of the article found 3 findings, namely: 1) music genre, 2) duration of music therapy, 3) sessions in music therapy. Music therapy to deal with anxiety problems in post-stroke patients is by paying attention to the music genre, the duration or duration of therapy, and the sessions or stages of music therapy. Music therapy intervention can be carried out by nurses as an independent intervention, which can be applied to both post-stroke patients who are still inpatient and who are undergoing rehabilitation
Co-Authors Astika Widy Utomo, Astika Widy Elisabeth Yunita Sofiana Mbau Handayani, Fitria Santoso Jaeri Wafi Banadzir Resya