Garuda - Garba Rujukan Digital

Systematic Review : Determinan Faktor yang Memengaruhi Kepatuhan Pengobatan Pasien Diabetes Tipe 2 di Indonesia Much Ilham Novalisa Aji Wibowo; Nanang Munif Yasin; Susi Ari Kristina; Yayi Suryo Prabandari
Media Penelitian dan Pengembangan Kesehatan Vol 31 No 4 (2021)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/mpk.v31i4.4855

Adherence to pharmacological therapy is the main key in the treatment of diabetes but has not received full attention by clinicians. Several systematic reviews of medication adherence factors have been carried out in several regions of the country. However, it does not feature studies from Indonesia. This study aims to review the factors that can influence diabetes medication adherence in Indonesia. Systematic literature reviews were carried out through searching the database of National (Garuda and Sinta) and International (PubMed and Science Direct) journals. Research that met the inclusion criteria and published in January 2011 - December 2020. The quality of the study was assessed using SQAT guidelines. The research reporting method uses PRISMA guidelines. Adherence factors are classified based on the domain of compliance factors according to World Health Organizatin (WHO). A total of 370 scientific research from the Garuda database (n = 36); Science direct (n = 108); PubMed (n = 18); Sinta (n = 208). Three hundred forty-one (341) studies were excluded, 29 full-text screening, 16 research articles met the inclusion criteria for analysis. Factors that affect adherence to diabetes medication are social and economic (income, education level, and occupation); labor and health system factors (health workers); patient therapy factors (number of diabetes medicines, frequency of taking medication, and drug product); factors patient disease (blood sugar levels, duration of illness); patient factors (gender, emotional factors, social support, level of knowledge and treatment satisfaction); anddisease management factors (counseling and pharmacy education). Factors that affect adherence to diabetes medication in Indonesia are very diverse and multi-factorial. These factors can serve as targets for relevant interventions. Clinicians need to consider adjusting the frequency of taking medication and providing social support to diabetes patients. Abstrak Kepatuhan terhadap terapi farmakologi merupakan kunci utama pengobatan penyakit diabetes, tetapi belum mendapat perhatian penuh oleh para klinisi. Beberapa systematic review faktor kepatuhan telah dilakukan di beberapa kawasan negara. Namun, tidak menampilkan studi dari Indonesia. Penelitian ini bertujuan untuk meninjau secara sistematis faktor-faktor yang dapat memengaruhi kepatuhan minum obat diabetes melitus (DM) di Indonesia. Systematic literature review dilakukan melalui pencarian pada database jurnal Nasional (Garuda dan Sinta) dan Internasional (PubMed dan Science Direct). Penelitian yang sesuai dengan kriteria inklusi dan dipublikasikan pada Januari 2011 – Desember 2020. Kualitas penelitian dinilai menggunakan panduan SQAT. Metode pelaporan penelitian menggunakan pedoman PRISMA. Faktor kepatuhan diklasifikasikan berdasarkan domain faktor kepatuhan menurut World Health Organization (WHO). Sebanyak 370 artikel ilmiah penelitian dari database Garuda (n=36); Science Direct (n= 108); PubMed (n= 18); Sinta (n= 208). 341 artikel penelitian dieksklusi, 29 artikel skrining full text, dan 16 artikel penelitian memenuhi kriteria inklusi untuk dianalisis. Faktor yang memengaruhi kepatuhan minum obat diabetes adalah faktor sosial dan ekonomi (penghasilan, tingkat pendidikan, dan pekerjaan), faktor tenaga dan sistem kesehatan (tenaga kesehatan), faktor terapi pasien (jumlah obat diabetes, frekuensi minum obat, dan produk obat), faktor penyakit pasien (kadar gula darah, durasi penyakit), faktor pasien (jenis kelamin, faktor emosional, dukungan sosial, tingkat pengetahuan, dan kepuasan pengobatan), dan faktor pengelolaan penyakit (konseling dan edukasi farmasi). Faktor yang memengaruhi kepatuhan minum obat DM di Indonesia sangat beragam, danmultifaktor. Faktor tersebut dapat berfungsi sebagai target intervensi yang relevan. Para klinisi perlu mempertimbangkan penyesuaian frekuensi minum obat dan pemberian dukungan sosial kepada pasien DM.

Pengaruh Intervensi Apoteker terhadap Tingkat Bahaya Drug-Related Problems pada Pasien Geriatrik Rawat Inap Margarita Krishna Setiawati; Nanang Munif Yasin; I Dewa Putu Pramantara
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.66776

Geriatric patients are at high risk of Drug-Related Problems (DRPs) associated with multimorbidity, physiologic changes, and pharmacologic alterations, that caused by the aging process. The pharmacist plays an important role in optimizing the effectiveness and safety of the patient’s drug therapies. This study aims to know the effect of pharmacist intervention in reducing the harmful levels of DRPs and to know the factors associated with the reduction of DRPs harm level in hospitalized geriatric patients. This research uses quasi-experimental study with a one-group pretest and posttest design. This research was conducted in Panti Rapih Hospital between March-April 2021, with patients’ inclusion criteria of ≥ 60 years old, with internal diseases cases, and identified DRPs in the therapy. The exclusion patient criteria are hospitalized in the intensive unit and Covid-19 ward. A pharmacist reviewed patient drug therapy, identified and solved DRPs. The harm level of DRPs was compared before and after pharmacist interventions. The harm level of DRPs was determined through professional adjustment according to The Harm Associated with Medication Error Classification tools, then analyzed using Wilcoxon test with a level of confidence 95%. Factors of age, the number of drugs received by the patient, comorbidities, and acceptance of the intervention were investigated for their effect on reducing the harm level of DRPs using a multivariate logistic regression test. A total of the research subject were 28 inpatients, with 47 DRPs identified. The most frequent DRPs were adverse drug reactions (27,66%). Among all interventions, 77,36% of them were accepted with full implementation. The pharmacist intervention resulted in a significant reduction in the harm level of both potential and actual DRPs (p < 0,05). A factor of the number of drugs received by patients and acceptance of pharmacist intervention was associated with the reduction of the harm level of DRPs (p < 0,05). This study shows that multidisciplinary collaboration is needed in the care of geriatric patients.

Perbandingan Efektivitas Penggunaan Nifedipin Dengan Metildopa Dalam Mengontrol Tekanan Darah Pasien Preeklamsia Sara Septi Widayani; Fita Rahmawati; Nanang Munif Yasin
Majalah Farmaseutik Vol 18, No 3 (2022)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v18i3.64894

Preeklamsia merupakan salah satu gangguan hipertensi selama kehamilan dimana salah satu tanda yang dialami oleh pasien adalah terjadinya peningkatan tekanan darah yang ditunjukkan dengan peningkatan tekanan darah sistolik ≥140 mmHg dan atau tekanan diastolik ≥90 mmHg. Belum banyak bukti yang menunjukkan pilihan terapi paling efektif bagi pasien preeklamsia untuk mengatasi hipertensi selama kehamilan. Tujuan dari penelitian ini adalah membandingkan efektivitas dan profil keamanan terapi antihipertensi yaitu nifedipin dengan metildopa pada pasien preeklamsia. Penelitian ini dilakukan menggunakan metode kohort retrospektif yang dilakukan di RSUD Tidar Magelang selama 3 bulan. Analisis statistik efektivitas diukur berdasarkan penurunan tekanan darah setelah penggunaan antihipertensi menggunakan independent t-test sementara profil keamanan diukur berdasarkan kejadian hipotensi setelah penggunaan antihipertensi. Pengukuran tekanan darah diamati selama 48 jam pasien menjalani rawat inap. Besar sampel penelitian ini adalah 56 dimana 34 pasien mendapat terapi nifedipin dan 22 pasien mendapat terapi metildopa. Hasil deskriptif karakteristik antara kedua kelompok menunjukkan tidak dapat perbedaan antara kelompok nifedipin maupun metildopa (p>0.05). Rata-rata tekanan darah sistolik setelah penggunaan nifedipin adalah 131.15±14.90 dan kelompok metildopa 130.23±12.42(p=0.952). Rata-rata tekanan darah diastolik setelah penggunaan nifedipin adalah 86.59±10.18 dan kelompok metildopa 85.14±7.92(p=0.738). Tidak terdapat perbedaan efektivitas dan profil keamanan pada pasien preeklamsia dengan pemberian nifedipin maupun metildopa.

Hubungan Tingkat Pengetahuan dan Kepatuhan Terhadap Luaran Klinik Pasien Diabetes Mellitus melalui Metode Brief Counseling di Puskesmas di Kabupaten Pemalang Nanang Munif Yasin; Irrene Wulan Syafitri; Ika Puspita Sari
Majalah Farmaseutik Vol 18, No 4 (2022): in press
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v18i4.74919

Pandemi COVID-19 menyebabkan terjadinya penurunan interaksi kegiatan rutin PROLANIS pasien Diabetes Mellitus (DM) tipe 2 di fasilitas kesehatan tingkat pertama. Tujuan dari penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan dan kepatuhan terhadap luaran klinik pasien DM tipe 2 setelah pemberian brief counseling oleh apoteker. Jenis penelitian ini adalah quasi-experimental dengan metode pretest and posttest design with control group. Penelitian ini dilakukan secara prospektif untuk menganalisis hubungan tingkat pengetahuan dan kepatuhan terhadap luaran klinik pasien Diabetes Mellitus setelah pemberian brief counseling. Tingkat pengetahuan diukur menggunakan kuesioner Diabetic Knowledge Questionnaire-24 (DKQ-24), tingkat kepatuhan diukur menggunakan kuesioner Morisky Green Levine Scale (MGLS), dan luaran klinik pasien DM tipe 2 berupa glukosa darah puasa (GDP) di Puskesmas di Kabupaten Pemalang pada periode Oktober hingga November 2021. Analisis data karakteristik subjek penelitian menggunakan metode deskriptif dan disajikan dalam bentuk presentasi dan frekuensi. Analisis untuk mengetahui hubungan antara tingkat pengetahuan dan kepatuhan terhadap luaran klinik menggunakan uji chi-square dengan tingkat kepercayaan 95% (α = 0,05). Penelitian ini terdiri dari 32 pasien pada masing-masing kelompok kontrol dan intervensi. Hasil analisis deskriptif penelitian ini menunjukkan tidak terdapat perbedaan data karakteristik subjek penelitian pada kelompok kontrol dan intervensi (p>0,05). Hasil analisis bivariat terkait korelasi menunjukkan adanya hubungan antara tingkat pengetahuan terhadap luaran klinik (p=0,000), dan tingkat kepatuhan terhadap luaran klinik pasien DM tipe 2 (p=0,000). Berdasarkan hasil penelitian tersebut, dapat disimpulkan bahwa ada hubungan yang bermakna antara tingkat pengetahuan dan kepatuhan terhadap luaran klinik pasien DM tipe 2 setelah pemberian brief counseling oleh apoteker.

Pengaruh Edukasi oleh Apoteker dengan Metode Brief Counseling terhadap Pengetahuan, Kepatuhan dan Glukosa Darah Pasien DM Tipe 2 di Puskesmas Kabupaten Pemalang Irrene Wulan Syafitri; Nanang Munif Yasin; Ika Puspita Sari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 13, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.74821

The problem currently encountered by Diabetes Mellitus (DM) patients is a decrease interaction in routine activities carried out at first-level health facilities due to the Covid-19 pandemic. This study is to determine the effect of education by pharmacists with media brief counseling on the knowledge, compliance, and clinical outcomes of DM patients. This type of research is a quasi-experimental method with a pretest and posttest design with the control group. This study was conducted prospectively to analyze the effect of brief counseling-based pharmaceutical services by pharmacists on the level of knowledge measured using the Diabetic Knowledge Questionnaire-24 (DKQ-24), the level of compliance was measured using the Morisky Green Levine Scale (MGLS) questionnaire, and the clinical outcomes of type 2 DM patients at the Puskesmas in Pemalang Regency from October to November 2021. The analysis to measure the bivariate differences in one group used the paired sample t-test, and the bivariate differences between groups were measured using the independent sample t-test. This study consisted of 32 patients in each control and intervention groups. The descriptive analysis of this study showed no differences in data on patient characteristics in the control and intervention groups (p>0.05). The results showed that there was an increase in patient knowledge from 12,66±2,43 to 21,75±1,81 (p=0,000) and an increase in patient compliance from 2,03±0,96 to 0,25±0,51 (p=0,000) after being given brief counseling. The clinical outcomes of DM patients showed that there was an improvement from 177,63±82,4 to 159±58,1 (p=0,002). Based on these results, it can be concluded that there is an effect of education by a pharmacist using the brief counseling method on the level of knowledge, compliance, and clinical outcome of type 2 DM patients.

Analisis Medication Error di Instalasi Farmasi Rawat Jalan RSPAD Gatot Soebroto Jakarta Pusat Ayyoehan Tiara Annisa; Nanang Munif Yasin; Susi Ari Kristina
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 13, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.82186

Medication errors (MEs) have an impact on drug service inaccuracies and endanger patients at risk through a variable number of accidents, so it is necessary to conduct different methods and definitions study. This study aimed to analyze MEs and causing factors in the Outpatient Pharmacy Installation of Gatot Soebroto Army Hospital. A mixed method study between quantitative and qualitative was conducted. A quantitative study was carried out by analyzing outpatient prescriptions to identify MEs with a checklist instrument and interviewing informants to find out some factors causing MEs. After the data generated from an interview, data were collected as a total of causing MEs, so the factors causing MEs could be determined. Data analysis was carried out descriptively. The results showed MEs in each Outpatient Pharmacy Installation of Gatot Soebroto Army Hospital. Errors at the BPJS Outpatient Pharmacy Installation consisted of prescribing errors (41,6%), transcribing errors (4,6%), and dispensing errors 15,7%). Errors at the Kartika Pavilion Outpatient Pharmacy Installation consisted of prescribing errors (12,4%), transcribing errors (2,4%), and dispensing errors (0,7%). BPJS Outpatient Pharmacy Installation has the highest medication errors (61,8%) in Gatot Soebroto Army Hospital compared to the Kartika Pavilion Outpatient Pharmacy Installation (15,5%) which was caused by the number of patients being larger and not comparable with the minimum number of staff. Other factors that cause ME include human factors such as the performance of staff and fatigue, system factors such as manual recipes and the absence of an e-prescription system, and environmental factors such as a busy work environment.

Gambaran Kepatuhan Penggunaan Obat Antituberkulosis pada Pasien Tuberkulosis Paru di Puskesmas Pahandut Kota Palangkaraya Anna Singgih D.P. Priyaputranti; Fita Rahmawati; Nanang Munif Yasin
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 13, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.83777

Tuberculosis is a communicable disease caused by Mycobacterium tuberculosis. Indonesia's health profile stated that the number of tuberculosis cases in 2021 was 397,377 cases, indicating an increase compared to 2020 of 351,936 cases. Medication adherence is crucial for the management of tuberculosis. Some failures of tuberculosis treatment are caused by non-adherence. Detection of medication adherence is important to help control tuberculosis. This study aimed to describe the medication adherence of antituberculosis drugs and the predictive factor among pulmonary tuberculosis of drug-susceptible tuberculosis. This study uses a cross-sectional design with retrospective data collection. Drug therapy monitoring and TB-01 form collected non-adherence identification from January to February 2023 at Puskesmas Pahandut, Palangkaraya city, which involved 35 patients. The predictive factor was identified by an interview with the patient, the treatment observers, and the chief tuberculosis programmer. Adherence was measured by medication left over at the visit. The results showed 24 (77%) adherent patients and 8 (23%) non-adherent patients. The predictive factor involved seven dimensions patient-centered (lack of motivation, forgetting to take medicine, unacknowledged information by public health care provider, confusion about how to take medicine), access factors, social and lack of role of the treatment observers. The improvement role of healthcare providers in public health centers and treatment observers is prominent in increasing patient adherence.

Title

Found 7 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 7 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 7 Documents
Search