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RASIONALITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN INFEKSI SALURAN KEMIH (ISK) DI INSTALASI RAWAT INAP RSUD UNDATA PALU TAHUN 2012 Febrianto, Aldu Wijaya; Mukaddas, Alwiyah; Faustine, Inggrid
Natural Science: Journal of Science and Technology Vol 2, No 3 (2013): Volume 2 Number 3 (December 2013)
Publisher : Univ. Tadulako

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ABSTRACT Urinary Tract Infection (UTI) is a bacterial infection of urinary tract that antibiotic was the first step on therapy. Antibiotic usage at hospitalized patients in developing country is 30-80%, but from all of that 20-65% antibiotic usage was considered inappropriate. It can raise resistance symptoms. This research is aimed to find out the rational of antibiotics usage including right indication, drug, dosage, frequency and duration in UTI patients. This research was descriptive research which was done retrospectively by looking at medical records of UTI patients, in order to explain or to illustrate the characteristics of each of the variables on this study including: patient characteristics, clinical characteristics and rationality of drug usage. The outcome of this study were as follow: Rationality treatment was 96.5 % in precise indications, right drug was 66.7%, right dosage was 53%, right frequency of antibiotic was 53%, and appropriate duration of antibiotic usage was 49.4 % . The use of antibiotic on UTI patients at Undata Palu Hospital in 2012, it could not be clasified as rational use yet.

IDENTIFIKASI DRUG RELATED PROBLEMS (DRPS) PADA PASIEN ANAK DEMAM BERDARAH DENGUE (DBD) DI INSTALASI RAWAT INAP RSUD UNDATA PALU TAHUN 2011 Rizky, Moh Zainal; Mukaddas, Alwiyah; Faustine, Inggrid
Natural Science: Journal of Science and Technology Vol 3, No 1 (2014): Volume 3 Number 1 (March 2014)
Publisher : Univ. Tadulako

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Drug Related Problems (DRPs) is an unexpected incident patients experience consequences or unforeseen consequences could potentially interfere with drug therapy to therapy outcomes. Dengue Hemorrhagic Fever (DHF) is one of diseases that occur in children and have a great chance to be the occurrence of DRPs. This study aims to find out the extent of potential DRPs in the incidence of DHF in children patients at the RSUD (public hospital) Undata Palu. This research was non experimental study using a descriptive retrospective study. The research was conducted by collecting data from the medical records of children patient (1-12 years old) undiagnosed DHF at RSUD Undata Palu. The data analyzed includes unnecessary drug therapy, wrong medicine, subtherapy dose and overdose. Based on the results of the study, we obtained that from 103 patients who met the criteria there were total of around 171 cases of DRPs cases, i.e. 103 cases (57.89%) was clasified as unnecessary drug therapy category, 25 cases (14,62%) was categorised as wrong medicine, 39 cases (22,81%) was over dose categories, and 8 cases (4,68%) was subtherapy dose category. The most often DRPs incidents occurs in this study were unnecessary drug therapy should be as large as 57,89 % of the total cases of DRPs.

EVALUASI PENGGUNAAN KOMBINASI ZINK DAN PROBIOTIK PADA PENANGANAN PASIEN DIARE ANAK DI INSTALASI RAWAT INAP RSUD UNDATA PALU TAHUN 2013 Lolopayung, Mardiyani; Mukaddas, Alwiyah; Faustine, Inggrid
Natural Science: Journal of Science and Technology Vol 3, No 1 (2014): Volume 3 Number 1 (March 2014)
Publisher : Univ. Tadulako

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Diarrhea is one of the main causes of child morbility and mortality in developing countries. Giving zinc and probiotics to children who get diarrhea, it can give positive impact on the incidence of diarrhea. This research aimed to evaluate the use of zinc and probiotics in treatment of children diarrhea. This research was conducted by using prospective method to children diarrhea in children?s ward Catelia at RSUD Undata Palu from June to September 2013. The subject on this research were divided into 2 groups, test and control group. The test group received therapy Oral Rehydration Salts (ORS), in combination to zinc ? probiotic treatment, and the control group only received ORS. Observed variable are the change of stool consistency, frequency, diarrhea duration, and lenght of stay. The result of changing stool consistency in test group was better than it in control group. The mean frequency of diarrhea while out in the test group was 1,27 ± 0,45 and it in control group was 1,53 ± 0,56. Lenght of stay in treated group (3,27 ± 1,26) was shorter than it in control group (3,77 ± 1,00). The use of zinc and probiotics for children diarrhea patients have significant effect on stool consistency, diarrhea frequency, diarrhea duration and lenght of stay (p=0,000).

RASIONALITAS PENGGUNAAN ANTIPSIKOTIK PADA PASIEN SKIZOFRENIA DI INSTALASI RAWAT INAP JIWA RSD MADANI PROVINSI SULAWESI TENGAH PERIODE JANUARI-APRIL 2014 Fahrul, Fahrul; Mukaddas, Alwiyah; Faustine, Ingrid
Natural Science: Journal of Science and Technology Vol 3, No 2 (2014): Volume 3 Number 2 (August 2014)
Publisher : Univ. Tadulako

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Schizophrenia is a severe mental disorder, that antipsychotics was effective therapy to treat it. There are 50 million sufferers in the world, 50% did not receive appropriate treatment and 90% of patients who did not receive the proper treatment in developing country. This research is aimed to find out rationality of antipsychotic usage includes right indication, drug, patient, dosage, and frequency in Schizophrenia Patient Department of Mental health in Madani Hospital of Central Sulawesi, in the period of January-April 2014. This research is a descriptive study, prospectively done by collecting primary data which was observation and interview, and secondary data was from the schizophrenia patient medical record. Data analysis was done by descriptive quantitative to provide an overview of the characteristic of each study variables including patient characteristic, clinical characteristic, and rational use of drug. The obtained results in rationality treatment was as follows : 100% precise indications, 90.4% right drug, 87.8% right patient, 81.6% right dosage and 90.4% appropriate frequency of antipsychotic use. Antipsychotic usage in schizophrenia Patient at mental health department of Madani Hospital of Central Sulawesi cannot be stated as rational yet.

PROFIL PENGOBATAN PASIEN DIABETES MELLITUS TIPE 2 DI INSTALASI RAWAT INAP RSUD UNDATA PALU TAHUN 2012 Yulianti, Sri Rahayu; Mukaddas, Alwiyah; Faustine, Inggrid
Natural Science: Journal of Science and Technology Vol 3, No 1 (2014): Volume 3 Number 1 (March 2014)
Publisher : Univ. Tadulako

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Diabetes mellitus (DM) is a metabolic disease prevalence increasing year by year. DM disease characterized by hyperglikemia that caused by abnormalities of insulin secretion, insulin activity or both. DM consists of two main types, namely DM type 1 and type 2. This research aims to know the profile of the treatment of type 2 DM in Undata hospital using method a retrospective medical record by noting that in accordance with the criteria of inclusion and exclusion. Among 147 population, 69 was taken as samples, then its characteristic were described based on each variable, resulting in a frequency distribution and proportion of each variable. The results showed that the most common therapy for type 2 DM was rapid acting insulin (novorapid), and the most common used of oral antidiabetic was metformin, and is most often treatment was combination of metformin and glimepirid.

KESESUAIAN PELAKSANAAN STANDAR PELAYANAN MINIMAL (SPM) BIDANG FARMASI DI INSTALASI FARMASI RUMAH SAKIT UNDATA PALU Faradillah, Nurul; Mukaddas, Alwiyah; Diana, Khusnul
Natural Science: Journal of Science and Technology Vol 6, No 2 (2017): Volume 6 Number 2 (August 2017)
Publisher : Univ. Tadulako

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This study aims to determine the suitability of the implementation of the Pharmacy Minimum Service Standards in the hospital at pharmacy section that includes: the length of service waiting time of compounded and available drugs, no error incident of drug administration and prescribing in refer to the formulation at the pharmacy installation, outpatient unit, in Undata Hospital, Palu. This study is a descriptive with quantitative data retrieval. Samples were prescription entered at the Undata hospital in the period from February to May 2016 including 12 sheets of cash prescription, 10 sheets of cash compounded prescription, 188 sheets of guarantee prescription and 187 sheets of guarantee compounded prescription. The results showed that the average length of services waiting time of cash prescriptions was 06 minutes 12 seconds, guarantee prescriptions was 07 minutes 01 seconds, cash compounded prescriptions was 17 minutes 02 seconds, guarantee compounded prescriptions was 16 minutes 05, no error incidence of drug administration was 100% and prescribing in refer to the formularium was 66.2%. These were in accordance to the standard of Kepmenkes RI No. 129 year 2008, except for prescribing in refer to the formularium. Therefore, it is suggested for drugs order should follow the hospital formularium

PERBANDINGAN EFEKTIVITAS ANTIBIOTIK GOLONGAN SEFALOSPORIN GENERASI KETIGA PADA PASIEN DEMAM TIFOID DI RUMAH SAKIT DAERAH MADANI PROVINSI SULAWESI TENGAH PERIODE 2017 Sunaryani, Rachelia; Mukaddas, Alwiyah; Tandah, M. Rinaldhi
Jurnal Ilmiah Medicamento Vol 5 No 1 (2019): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v5i1.852

Demam tifoid merupakan penyakit sistemik akut yang disebabkan oleh infeksi bakteri Salmonella typhi. Sekitar 21 juta kasus dan 222.000 kematian terkait tifoid terjadi setiap tahun di seluruh dunia. Terapi antibiotik efektif menurunkan demam dan gejala lainnya, menurunkan mortalitas dan mencegah kekambuhan. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan retrospektif untuk mengetahui antibiotik golongan sefalosporin generasi ketiga yang paling efektif terhadap pasien demam tifoid di RSD Madani Provinsi Sulawesi Tengah periode 2017, dengan menggunakan uji Kruskall-Wallis. Berdasarkan hasil penelitian disimpulkan bahwa sefotaksim lebih efektif dibandingkan sefoperazon dan seftriakson, dimana sefotaksim dapat menurunkan suhu lebih cepat (1,71 hari) dibandingkan sefoperazon (2,16 hari) dan seftriakson (2,25 hari) serta lama rawat inap lebih cepat (2,7 hari) dibandingkan sefoperazon (3,36 hari) dan seftriakson (3,92 hari) dengan nilai p < 0,05. Sedangkan pada hari hilangnya demam tidak terdapat perbedaan yang signifikan (p > 0,05) terhadap ketiga antibiotik tersebut.

PROFIL KADAR GLUKOSA DARAH PASIEN DIABETES MELLITUS TIPE 2 YANG MENGGUNAKAN ATORVASTATIN 20 MG DI RUMAH SAKIT MADANI, ANUTAPURA DAN UNDATA PERIODE 2015-2019 Lestari, Widya; Mukaddas, Alwiyah
Jurnal Ilmiah As-Syifaa Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.607

Atorvastatin is one of the lipophilic statins that can cause diabetes through some mechanisms, such as liphophilic properties, itâ€™s activities to insulin secretion, insulin signaling, and adiponectin levels. The purpose of this research is to know demographic data, profile of when blood sugar levels, and the time needed for atorvastatin to increase blood sugar when type 2 diabetes mellitus patients use atorvastatin for 20 mg. This research is observational descriptive research with retrospective data collection approach by looking at the usage of atorvastatin, with total samples 22 patients obtained from medical record data at Madani hospital, Anutapura and Undata in Palu in the period of 2015-2019. This research result shows that the demographic data of the average age of type 2 diabetes mellitus patients in which complications of dysplidemia that uses atorvastatin for 20 mg are in the age of 45-56 years old, female gender (57.14%), with the last education of Senior High School (38.09%) and occupation as Government Employees (33.33%), the time needed for atorvastatin 20 mg to increase blood sugar is 2 months (the difference is 26.38 mg/dl; percentage 19.52%) and the percentage of highest blood sugar increase is one year, which is 93.91%.

EVALUASI PENGGUNAAN SUPLEMEN KEHAMILAN PADA PASIEN WANITA HAMIL DI PUSKESMAS BULILI KOTA PALU PERIODE APRIL 2018 â€“ DESEMBER 2018 Mukaddas, Alwiyah; Hardani, Ririen; Fandi, Indra Dwi
Jurnal Ilmiah As-Syifaa Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.689

Anemia in pregnant women will increase the risk of new born babies with low birth weight, miscarriage, premature, risk of bleeding before and / or during labor can cause death to both of them. This research aims to determine the evaluation before and after pregnancy supplement to pregnant women at Puskesmas Bulili, Palu, April - December 2018. This is a quantitative research with a retrospective approach. There are 44 females without the anemia and 22 at the anemia group. Pregnant women are said to be anemic when their hemoglobin or red blood levels are less than 11.0 gr%. The results, the hemoglobin levels before and after the use of pregnancy supplements in the non-anemia were 11.7 gr / dl and 11.4 gr dl (p = 0.004; p <0.005), the anemia group 9.7 gr / dl and 11 , 3 gr / dl (p = 0.000; p <0.005, there was a significant change in hemoglobin level. The results showed no anemia group difference which smaller (0.3 g / dl) compared to the anemia group (1.6 g / rdl), with values (p = 0.317; p> 0.005) which means no significant difference in hemoglobin levels after pregnancy supplementation

PERBANDINGAN MEDICATION ERROR PADA PERESEPAN ELEKTRONIK DAN PERESEPAN MANUAL PADA TAHAP PRESCRIBING DI APOTEK KOTA PALU Mukaddas, Alwiyah; Faustine, Ingrid; Nofriyanti, Nofriyanti
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i2.700

Â Prescribing drugs is now growing, as evidenced by the existence of electronic prescribing that have been applied in several hospitals and pharmacies. The development of this prescribing method does not rule out the possibility of increasing the incidence of medication errors in prescribing. So, it is necessary to identify the prescribing that has been implemented, especially in drugstore at Palu City. The purpose of this study was to look at the comparison of medication errors at the prescribing stage which included aspects of prescribing completeness and therapeutic errors in electronic prescribing at Drugstore X and manual prescribing at Drugstore Y in Palu city in 2018. This type of research is a descriptive study with retrospective data collection. Samples taken in the form of secondary data are prescribing using purposive sampling method. The results obtained in this study are, the prevalence of medication error at the prescribing stage of electronic prescribing in drugstore at Palu City includes data,Â patient's body weight is 2%, doctor's license 100%, doctor's telephone number 100%, doctor's initial 100%, dosage form 97% and 90% strength of the drug. While the prevalence of medication error at the prescribing stage of manual prescribing in Drugstore Palu City is data, the patient's age is 2%, the patient's body weight is 99.1%, the patient's sex is 100%, the doctor's license is 91.6%, the doctor's telephone number is 80% , initial doctor 42.7%, 88% dosage form and 65% drug strength. Based on these results, it can be concluded that the use of electronic prescribing is better than manual prescribing.

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