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All Journal Padjadjaran Journal of Dentistry
Asia Rehman
Universiti Sains Malaysia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Arterial stiffness in patients with localized and generalized severe chronic periodontitis: A preliminary study Erry Mochamad Arief; Ho Ting Khee; Asia Rehman; Akram Hassan; Mohd. Fadhli Khamis
Padjadjaran Journal of Dentistry Vol 21, No 3 (2009): November 2009
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.83 KB) | DOI: 10.24198/pjd.vol21no3.14111

Abstract

A relationship between periodontal disease and cardiovascular disease (CVD) has been reported in several studies. This association was explained based on the chronic systemic inflammatory response which may lead to arterial stiffness in chronic periodontitis (CP). To compare arterial stiffness as carotid-femoral pulse wave velocity (PWV) between patients with localized severe CP (LSCP) and generalized severe CP (GSCP). Five patients with LSCP and 12 patients with GSCP were recruited in a cross-sectional study. Subjects were excluded if they had systemic diseases other than CP. Diagnosis of LSCP and GSCP was made based on probing depth and radiographic bone loss. Carotid-femoral PWV was measured using the Complior® machine. Data were analyzed using SPSS. Carotid-femoral PWV was higher among patients with GSCP as compared to those with LSCP although the difference did not reach a significant level. Median (interquartile range) PWV was 7.5 (1.50) and 7.0 (1.03) m/sec respectively in patients with GSCP and LSCP (p = 0.224). Among patients with CP, aorta is stiffer in GSCP than in LSCP
Co-Authors Akram Hassan Erry Mochamad Arief Ho Ting Khee Mohd. Fadhli Khamis