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Teh putih (Camellia sinensis) dan kelor (Moringa oleifera) sebagai antihiperglikemia pada tikus Sprague dawley yang diinduksi streptozotocin Amalia Rahma; Rina Martini; Clara Meliyanti Kusharto; Evy Damayanthi; Dadan Rohdiana
Jurnal Gizi dan Pangan Vol. 12 No. 3 (2017)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (353.717 KB) | DOI: 10.25182/jgp.2017.12.3.179-186

Abstract

This study aims to examine the antihyperglycemic effect of white tea (Camellia sinensis) and Moringa oleifera when administered as a single component and as mixture in streptozotocin-induced diabetic rats. The study design was experimental. The first step was to analyze epigallocathecingallat (EGCG) content as standard with High Performance Liquid Chromatography (HPLC) method. The second step was intervention in Sprague dawley rats induced by streptozotocin 40 mg/kgBW. Intervention held for 21 days with given white tea (WT), M. oleifera (MO), mixture of white tea and M. oleifera (WT+MO) and green tea (GT) as positive control with reference dose 100 mg/kgBW EGCG. Rats blood glucose and body weight were measured. The results are WT having the highest content of EGCG (4.46%). MO and WT+MO only have 2.42% and 2.46% of EGCG while GT as control is the lowest (1.29%). Measurements of blood glucose and body weight in group that given WT or MO as single component showed no significant difference with control negative group (p>0.05). Blood glucose decreased significantly in group WT+MO (p<0.05). Administration of WT+MO was able to maintain a stable body weight during the intervention period (p>0.05). The combination of white tea and M. oleifera has better ability as an antihiperglycemic agent compared to single component.
The Potential of White Tea (Camellia sinensis) and Kelor (Moringa oleifera) in Improving Lipid Profile and Histopathological Features of Pancreas in Streptozotocin-Induced Rats Rina Martini; Amalia Rahma; Clara Meliyanti Kusharto; Hadi Riyadi; Cece Sumantri; Dadan Rohdiana
Jurnal Gizi dan Pangan Vol. 14 No. 1 (2019)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.248 KB) | DOI: 10.25182/jgp.2019.14.1.23-30

Abstract

This study aimed to examine the potential of white tea and kelor in improving lipid profile and histopathological features of the pancreas in streptozotocin-induced Sprague-Dawley rats. The research design was an experimental study with post-test control group design. Catechin content were analysed using High-Performance Liquid Chromatography. Twenty Sprague-Dawley rats (out of 24 rats, 12-week old, 200-300 g) were induced with intraperitoneal injection of streptozotocin at a dose of 40 mg/kg BW. Four groups of rats received one of the green tea (GT), white tea (WT), kelor (K), or the mixture of white tea and kelor (WTK) with a dose of epigallocatechin-3-gallate (EGCG) at 100 mg/kg BW administered orally for 21 days. Measurements of the lipid profile and preparation of histopathological features of the pancreas were performed after the intervention was completed. The results showed that white tea had the highest concentrations of catechin (39.17%), gallic acid (1.09%), EGCG (4.46%), and epicatechin (9.61%) compared to the other tea groups. The TG levels of the WTK group (95±19.35 mg/dl) were significantly different (p<0.05) from the WT and K groups but not significantly different from the normal (105.8±23.89 mg/dl), DM and GT groups. Meanwhile, the HDL levels did not show significant differences in each intervention group (p>0.05). The mean diameter of the islets of Langerhans in the DM group (9.16± 2.56 μm) was significantly different (p<0.05) from the WT (20±8.94 μm), K (17.16±5.26 μm), WTK (18.66±4.17 μm), and N (21.07±8.49 μm) groups but not significantly different from the GT group (14.33±5.24 μm). The histopathological features of the pancreas showed an increase in the diameter of the islets of Langerhans in WT, K, and WTK groups. This study revealed that the mixture of white tea and kelor had the potential to ameliorate triglyceride levels and histopathological features of the pancreas in streptozotocin-induced Sprague-Dawley rat.
Karakteristik dan Tingkat Kecukupan Energi Pasien Penyakit Infeksi dan Degeneratif yang Dirawat Inap di Rumah Sakit Annisa Rizkiriani; Rina Martini; Sesar Husen Santosa; Ridwan Siskandar
Jurnal Sains Indonesia Vol 2 No 2 (2021): Volume 2, Nomor 2, 2021 (Juli)
Publisher : PUSAT SAINS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59897/jsi.v2i2.46

Abstract

The patient's energy adequacy level can reduce morbidity and mortality, as well as accelerate the healing process and reduce the length of time hospitalized for patients. The purpose of this study was to determine the characteristics and level of energy adequacy of patients with infectious and degenerative diseases who were hospitalized at the hospital. The design of this study was coss sectional. The number of samples was 30 hospitalized patients whose consumption was observed for 3 days. samples were selected purposively in hospitals in Bogor and Jakarta. Statistical analysis using Mann Whitney test, pearson correlation regression, and stepwise regression using Microsoft Excel and Minitab. The results showed that there was a relationship between age, nutritional status, blood pressure, and body temperature with the type of disease. More than one-third of the patient's energy adequacy level was in the severe deficit category. The determinant factors for the type of disease are age and the level of energy adequacy.
POTENSI EKSTRAK DAUN KERSEN SEBAGAI BAHAN SANITASI KERABANG TELUR PADA PROSES PENETASAN TELUR ITIK ALABIO: The Potential Of Cherry Leaf Extract (Mutinga calabura L) As A Sanitary Agent For Eggshell In The Alabio Ducks Hatching Process Gilang Ayuningtyas; Rina Martini; Wina Yulianti
Jurnal Sains Terapan : Wahana Informasi dan Alih Teknologi Pertanian Vol. 10 No. 2 (2020): Jurnal Sains Terapan, Volume 10 Nomor 2, Tahun 2020
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.9 KB) | DOI: 10.29244/jstsv.10.2.50-61

Abstract

The objective of this research was to study the potential of cherry leaf extract as natural sanitizer agent for Alabio eggshell in hatching process. A number of 533 of Alabio hatching eggs were used in this study. Hatching eggs produced from College of Vacational Studies IPB University, were collected three times a day. Three hundred thirty-three hatching eggs were divided into five treatment groups. The first group was considered as control, the second was dipping into commercial disinfection, and the third and the fifth gruop were dipping into cherry leaf extract 250 ppm, 500 ppm, and 750 ppm respectively. The results showed cherry leaf extract has secondary metabolite compounds : alkaloids, flavonoids and tannins. All of these secondary metabolite compounds have a role as antibacterial agent. cherry leaf extract 750 ppm shows the same potential as commercial disinfectants in reducing the microbial population in eggshells. The dipping treatment of 750 ppm cherry leaf extract in alabio duck hatching eggs resulted in the lowest embryo mortality rate compared to other treatments (9.3%). Key words: Alabio duck, cherry leaf extract, hatchery, total plate count of eggshell
PENGARUH METODE EKSTRAKSI DAN POLARITAS PELARUT TERHADAP KADAR FENOLIK TOTAL DAUN KERSEN (Muntingia calabura L): Effect of Extraction Method and Solvent Polarity on Total Phenolic Content of Cherry Leaves (Muntingia calabura L) Wina Yulianti; Gilang Ayuningtyas; Rina Martini; Ika Resmeiliana
Jurnal Sains Terapan : Wahana Informasi dan Alih Teknologi Pertanian Vol. 10 No. 2 (2020): Jurnal Sains Terapan, Volume 10 Nomor 2, Tahun 2020
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.223 KB) | DOI: 10.29244/jstsv.10.2.41-49

Abstract

ABSTRACTThe method of extraction and the type of solvent used during extraction will influence effectiveness of the extraction and compound extracted. The aim of this research was determined the effect of extraction methode and solvent polarity on total phenolic content of cherry leaves (Muntingia calabura L). Extraction of cherry leaves used maceration and soxhelation methods with ethanol and chloroform as solvents. The total phenolic contain was determined by visible spechtrophotometer at 765 nm. It has been showed that the soxhletation method was a higher yield value than the maceration methods with the highest yield value showed by ethanol extract, it was 13,29% w/w. Otherwise maceration method showed a higher total phenolic contain with the highest total phenolic contain showed by ethanol extract, it was 10,70% GAE.
Greeny Quiche Bites, Alternatif Snack dengan Sirih Bumi (Peperomia Pellucida) Bagi Remaja Annisa Rizkiriani; Ani Nuraeni; Vieta Annisa Nurhidayati; Lisya Mutiara Ramadanti; Muhammad Nurmahmudi; Siti Intan Permatasari; Rina Martini; Firman Muhammad Basar
Jurnal Sains Indonesia Vol 4 No 1 (2023): Volume 4, Nomor 1, 2023 (Maret)
Publisher : PUSAT SAINS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59897/jsi.v4i1.126

Abstract

Greeny Quiche Bites is a snack filled with daun sirih bumi as an alternative snack for adolescents. The aim of this research is to make Greeny Quiche Bites as an alternative snack with sufficient nutritional content for Adolescents. The results of this study show that each serving of 2 Greeny Quiche Bites, weighing approximately 100 g, contains 238 Cal of energy, 11.4 g of protein, 31.9 g of carbohydrates, 2.3 g of fiber, and 6.4 mg of iron. Greeny Quiche Bites contribute an average of 11,1% of the energy needs of adolescents aged 10-18 years. The overall category hedonic test results show that the panelists really like Greeny Quiche Bites. Based on the nutritional content, Greeny Quiche Bites can be used as an alternative snack with sufficient nutritional content and iron-rich for teenagers.