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Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet Arie Purwana; Budiono Budiono; Jose RL Batubara; Muhammad Faizi
Journal of Biomedicine and Translational Research Vol 6, No 1 (2020): April 2020
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v6i1.5474

Abstract

Background: The vegan diet in children provides the benefit of reducing the risk of being overweight and improving the fat profile. The risk that can occur in the provision of a vegan diet in children is anthropometric size below reference and low caloric intake. Growth hormone (GH) and Insulin like Growth Factors (IGFs) are powerful stimulators for longitudinal growth of bone and require insulin-like growth factor binding protein (IGFBPs) which acts as a transport protein for IGF-1. A vegan diet with lower calorie intake in children has lower IGF-I levels than children with an omnivorous diet.Objective: Examining the effect of vegan diets on IGF-1 levels, IGFBP-3 levels, and growth velocity.Methods: This study was done with a prospective cohort design. The study subjects were divided into two groups, namely the vegan group and the omnivorous group, then matched based on age and sex. During the study, anthropometric data collection, IGF-1 and IGFBP-3 levels measurements were done in both vegan children and omnivorous children.Results: During 6 months of observation, 22 subjects were divided into two groups, namely children with a vegan diet and children with an omnivorous diet. IGF-1 (ng / mL) in vegan children was 105.5 ± 47.3 compared to 102.7 ± 42.3 in omnivorous children with a value of p = 0.89. IGFBP-3 (ng / mL) in vegan children was 2146.4 ± 595.1 compared to 2142 ± 609.1 in omnivorous children with value of p = 0.99 and Growth Velocity (cm / 6 months) was 3.0 in vegan children (1.0-5.30), and 3.2 (2.6-6.5) in omnivorous children with value of p = 0.41.Conclusion:Children with vegan diet had IGF-1 level, IGFBP-3 level, and growth velocity that were the same as children with an omnivorous diet.
Intestinal Protozoa Infections in Relation to Nutritional Status of the Students Mandangin Island Elementary School 6 in Sampang Regency Marlinda Kurniati; Budiono Budiono; Sri Wijayanti Sulistyawati
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.081 KB) | DOI: 10.20473/juxta.V10I12019.25-28

Abstract

Introduction: Intestinal protozoa infections is a tropical infectious disease that can be found mainly in developing countries. It will cause some health problem such as undernutrition. This study was aiming to determine the correlation between the incidence of intestinal protozoa infections with the nutritional status of students Mandangin Island Elementary School 6 in Sampang Regency.Methods: This research used the cross-sectional study as the design and performed by doing a lab examination to determine the incidence of protozoa infections and analyze whether it has any correlation with changes in host nutritional status, recruited from students Mandangin Island Elementary School 6, from 19th to 21st of July 2017. Results: On microscopic examination found that 71.4% (n=30) samples are positive and 28,6% (n=12) are negative. On BMI-for-age measurement there are 4,8% obesity, 7,1% overweight, 73,8% normal, 9,5% thinness, and 4,8% severe thinness. Meanwhile, on height-for-age measurement there are 73,8% normal and 26,2% stunted . The incidence of  intestinal protozoa infections was correlated with the nutritional status using SPSS  (p= 0,375, p= 0,539, a= 5%).Conclusion: There was no significant correlation between intestinal protozoa infections with the nutritional status of students Mandangin Island Elementary School 6 in Sampang Regency. These conditions caused by the pathogenicity stage to cause a decrease in the nutritional state has not been reached.
Analysis of Diagnosis Delay on Lung Tuberculosis Patient in Porong Primary Health Care, East Java, Indonesia Muhammad Bagus Fidiandra; Budiono Budiono; Soedarsono Soedarsono
Jurnal Respirasi Vol. 7 No. 2 (2021): May 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (353.824 KB) | DOI: 10.20473/jr.v7-I.2.2021.53-58

Abstract

Introduction: The duration of diagnosis delay in tuberculosis (TB) control strategy is one of the problems in TB control program. There are a lot of adverse effects, such as increasing the risk of people to become more prone to TB transmission, infectivity period, and worsening the patient’s condition that can furthermore increase the mortality and morbidity numbers. This study aimed to analyze the delay behavior in the society, specifically in Porong, East Java.  Methods: The respondents filled a questionnaire, the answer was crosschecked and complemented with the medical record on the clinic. The data collected then were analyzed with binary logistic regression using SPSS.Results: From the total of 22 samples in this study, 11 of them were classified to be delayed (patients checked their symptoms 2 weeks after the symptoms started to appear). Some factors that might have an effect on the patient’s delay were education level, the patient’s knowledge about TB, and occupation that lead to the patient’s business. Meanwhile, factors like age, gender, and the distance between the patient’s house and the health facility might have an insignificant effect.Conclusion: Duration of patient delay contributed significantly to the duration of diagnosis delay, with the median duration of 29 days. Meanwhile, the duration of system delay that was found only ranging at 0-3 days. In this study, however, evidence of the independent factors might have an effect on the patient’s tendencies to delay treatment that had not yet proven by statistical analysis.
Diare Kronis pada Anak Berusia di Bawah Lima Tahun Grahana Ade Candra Wolayan; I Gusti Made Reza Gunadi Ranuh; Budiono Budiono; Alpha Fardah Athiyyah
Jurnal Ilmiah Kesehatan (JIKA) Vol. 2 No. 3 (2020): Volume 2 Nomor 3 Desember 2020
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.56 KB) | DOI: 10.36590/jika.v2i3.76

Abstract

Diarrhea is an endemic disease in Indonesia and has the potential to cause outbreaks that are often accompanied by death, even the mortality rate during outbreaks in 2017, amounting to 1.97%, had not yet reached the expected target by the government, which is less than 1%. This study aims to determine the distribution of sex, age, nutritional status based on weight/age, and how to leave the hospital for chronic diarrhea patients and to know the correlation between nutritional status based on weight/age and death cases of chronic diarrhea in children under five years old treated at RSUD Dr. Soetomo in the period 2015-2019. This research was a retrospective analytical and descriptive study using secondary data from a patient's electronic medical record. Results showed that out of 45 chronic diarrhea patients, 28 (62,2%) were male, 16 (35,6%) children were in the 0 - 5 months age group, 18 (40,0%) children had good nutritional status, 39 (86,7%) children were discharged from the hospital, and there was a significant correlation between nutritional status based on weight/age and death cases of chronic diarrhea in children (p = 0,017). It could be concluded that the majority of children with chronic diarrhea were male, were in the 0 - 5 months age group, had good nutritional status, and were discharged from the hospital which meant that their condition had improved or cured and there was a significant correlation between nutritional status based on weight/age with death cases of chronic diarrhea in children.