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All Journal Tropical Medicine Journal ELKHA : Jurnal Teknik Elektro Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Sari Pediatri Paediatrica Indonesiana Jurnal Gizi Klinik Indonesia

Roni Naning

Department Of Pediatrics, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Central Java

Author-ID : 328166

Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Electrical & Electronics Engineering Energy Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health

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Articles

Risk Factors of Pneumonia Among Under Five Children in Purbalingga District, Central Java Province Ni Kadek Nira; Dibyo Pramono; Roni Naning
Tropical Medicine Journal Vol 3, No 2 (2013): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

ABSTRACTIntroduction: Pneumonia is the leading cause of mortality and morbidity in young children and burden of disease disproportionately high in South-East Asia Region. Pneumonia incidence in Indonesia is sixth rank in the world. Pneumonia were leading causeof infants mortality about 23.8% and among children, pneumonia contribute 15.5% of total mortality after diarrhea. Risk factors associated with pneumonia are: individual, environment, and social economic.Objectives: The aim of study to identify relationship between individual, environment, and social economic risk factors with pneumonia incidence among under five children in Purbalingga District.Methods: This research was an analytical and observational study using case control design. Subjects were 210 children aged 2-60 month which consists of 105 cases and 105 controls. This study conduct at 9 Public Health centers in Purbalingga District on April to June 2013. Cases were children with pneumonia diagnose by trained doctor or paramedic. Controls were children without diagnosed pneumonia who visited the same Public Health Centers as cases. Results fromunivariate, McNemar test was used to bivariate analysis and conditional logistic regression in multivariate analysis with 95% confidence interval.Results: In the multivariate analysis showednot exclusively breastfed (OR=3.99, 95% CI=1.851-8.596), househumidity (OR=3.13, 95% CI=1.382-7.096), house ventilation (OR=6.62, 95% CI=2.847-15.369), overcrowding (OR=2.74, 95% CI=1.230-6.121) and without kitchen smoke hole (OR=6.14, 95% CI=1.932-19.497) had significant association to pneumonia incidence. Ventilation showed the highest risk for pneumonia incidence among under five children.Conclusion: Factors such as not exclusively breastfed, live in house with high humidity, lack of ventilation, over crowding and without kitchen smoke holewere risk factors for pneumonia among under five children. Ventilation was dominant risk factor for developing pneumonia. Promote breastfeeding and improve house condition such as improve house ventilation and make kitchen smoke hole could lead to reduction of pneumonia under five children.Keyword: under five children, pneumonia, risk factors, Purbalingga District

Anti-hepatitis B surface (anti-HBs) seroprotection in children with acute lymphoblastic leukemia post hepatitis B vaccination in Indonesia . Yustinah; Nenny Sri Mulyani; Roni Naning
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 01 (2014)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Children with acute lymphoblastic leukemia (ALL) receiving chemotherapy are at high risk fordeveloping hepatitis B infection. Protective effect of hepatitis B vaccination in children withALL in Indonesia has not been investigated yet. The aim of study was to determine the proportiondifference of anti-HBs seroprotection between children with ALL and without malignancy posthepatitis B vaccination. We had conducted a case-control study from January to February 2012at Dr. Sardjito General Hospital, Yogyakarta. We ascertained 1-15 years old children with ALLreceiving chemotherapy and without malignancy who had hepatitis B vaccination. Sixty sevenchildren were included in this study. Anti-HBs seroprotection level was measured using anenzyme-linked immunosorbent assay (ELISA). The results were analyzed using Chi-square test.Twenty one children (65.6%) with ALL and 13 children (37.1%) without malignancy showedanti-HBs seroprotection. The difference was statistically significant with p-value of 0.020(prevalence ratio [PR]=0.3; 95% CI=0.11-0.84). Both groups showed no significantly differenceof anti-HBs seroprotection according to either female gender, risk classification, or phase ofchemotherapy with p-value of 0.38 (PR =4; 95% CI=1.05-15.2), 0.248 (PR =3.37; 95%CI=0.58-19.6) or 0.214, respectively. In conclusion, the proportion of anti-HBs seroprotectionin children with ALL is higher than those without malignancy.

Prognostic predictor at Pediatrics Intensive Care Unit (PICU) with Pediatric Risk of Mortality III (PRISM III) scores Vita Susianawati; Purnomo Suryantoro; Roni Naning
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 02 (2014)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Various mortality prognostic scoring system are available for predicting mortality risk in PediatricIntensive Care Unit (PICU). The Pediatric Risk of Mortality III (PRISM III) scoring system is one ofthe main indicators used in the PICU. This study was conducted to evaluate the PRISM III asprognostic predictor in PICU. This was a cohort study involving 64 patients who admitted toPICU in Dr. Sardjito General Hospital, Yogyakarta and met inclusion and exclusion criteria. Theclinical state of patients were assessed and the PRISM III scores corresponding to the firs 24hours of hospitalization were calculated. Outcome analysis was defined either as death ordischarged from the hospital were recorded.Multivariateanalysiswas performed to find outindependent predictive factor that influence the outcome of death.The discriminative power ofthe model was calculated based on the receiver operator curve (ROC). The result showed thatmental status (relative risk/RR: 13.21; 95%CI: 1.18-14.80), White Blood Count/WBC (RR: 19.51;95%CI: 18.12-25.15) and Blood Urea Nitrogen/BUN (RR:22.87; 95%CI:1.85-28.20) were foundto be the main predictive factors of death in PICU. The cut off value of 51 of PRISM III scoreyielded the best sensitivity (83%) and specificity (69%). In conclusion,PRISM III score can beused as a prognostic predictor to determine the death risk ofpatients hospitalized at PICU.

Hubungan Kadar Vitamin C Plasma dengan Serangan Asma pada Anak Azwar Aruf; Roni Naning; Mei Neni Sitaresmi
Sari Pediatri Vol 16, No 2 (2014)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp16.2.2014.91-6

Latar belakang. Banyak faktor yang dapat memicu serangan asma. Perhatian terhadap peran nutrisi antioksidan serta stres oksidatif pada kejadian asma beberapa tahun terakhir ini semakin meningkat. Beberapa penelitian melaporkan bahwa kadar vitamin C plasma yang rendah merupakan faktor risiko serangan asma, meskipun masih kontroversial. Belum ada penelitian mengenai vitamin C plasma dan asma di Indonesia.Tujuan. Menilai apakah kadar vitamin C plasma rendah merupakan faktor risiko serangan asma pada anak, dengan cara membandingkan kadar vitamin C plasma anak asma dalam serangan dan anak asma tidak dalam serangan.Metode. Desain penelitian ini adalah penelitian kasus kontrol. Pengambilan sampel dilakukan secara konsekutif. Subyek adalah semua anak yang terdiagnosis asma dalam serangan dan tidak dalam serangan di RSUPDR. Sardjito Yogyakarta sejak April 2012 sampai dengan Agustus 2013. Subyek dibagi menjadi dua kelompok, 39 anak kelompok asma tidak dalam serangan dan 39 anak kelompok asma dalam serangan. Kadar vitamin C plasma diperiksa dengan metode kuantitatif spektofotometer.Hasil. Karakteristik subyek, antara lain umur, jenis kelamin, riwayat kontak hewan peliharaan, riwayat kontak tungau debu rumah, perokok pasif, alergi makanan, infeksi saluran pernapasan, kadar vitamin C plasma. Analisis bivariat dilakukan dengan uji kemaknaan (nilai p<0,05), dan rasio Odds. Kadar vitamin C plasma kelompok asma dalam serangan dan tidak dalam serangan tidak berbeda bermakna dengan nilai p=0,77 dan rasio Odds 1,18 (IK95%: 0,32;3,64). Infeksi pernapasan merupakan faktor risiko serangan asma yang bermakna dengan nilai p=0,006 dan rasio Odds 3,6 (IK 95% 1,41;9,19).

Lung function test in children with left-to-right shunt congenital heart disease Carolina Kurniawan; Indah Kartika Murni; Sasmito Nugroho; Noormanto Noormanto; Roni Naning
Paediatrica Indonesiana Vol 58 No 4 (2018): July 2018
Publisher : Indonesian Pediatric Society

Background Increased pulmonary blood flow may lead to abnormal lung function in children with left-to-right (L to R) shunt congenital heart disease. This condition has been linked to considerable mortality and morbidity, including reduced lung function. Objective To assess for lung function abnormality in children with L to R shunt congenital heart disease. Methods We conducted a cross-sectional study involving children aged 5-18 years and diagnosed with L to R shunt congenital heart disease at Dr. Sardjito Hospital from March to May 2017. Subjects underwent spirometry tests to measure forced expiratory volume-1 (FEV-1), forced vital capacity (FVC), and forced expiratory volume-1 (FEV-1)/forced vital capacity (FVC). Results Of 61 eligible subjects, 30 (49.2%) children had atrial septal defect (ASD), 25 (41%) children had ventricular septal defect (VSD), and 6 (9.8%) children had patent ductus arteriosus (PDA). Spirometry revealed lung function abnormalities in 37 (60.7%) children. Restrictive lung function was documented in 21/37 children, obstructive lung function in 11/37 children, and mixed pattern of lung function abnormality in 5/37 children. Pulmonary hypertension was found in 21 children. There was no significant difference in lung function among children with and without pulmonary hypertension (P=0.072). Conclusion Abnormal lung function is prevalent in 60.7% of children with L to R shunt congenital heart disease, of which restrictive lung function is the most common. There was no significant difference in lung function among children with and without pulmonary hypertension.

Hypovitaminosis D as a risk factor for severe autism spectrum disorder Diyah Rakanita Undang; Mei Neni Sitaresmi; Roni Naning
Paediatrica Indonesiana Vol 61 No 2 (2021): March 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.2.2021.82-8

Background Vitamin D is an important risk factor for autism spectrum disorder (ASD). However, research on hypovitaminosis D as a risk factor for severe ASD has been limited. To our knowledge, no such studies have been done in Indonesia. Objective To evaluate hypovitaminosis D as a risk factor for severe ASD. Methods This cross-sectional study included children aged 2-18 years who fulfilled the ASD DSM-5 diagnostic criteria. Subjects were consecutively sampled from April - June 2019 at the Child Growth and Polyclinic, Dr. Sardjito General Hospital, Yogyakarta. Assessment of ASD severity was carried out using the Childhood Autism Rating Scale Second Edition (CARS-2) questionnaire. Serum 25(OH)D examination was done in the Clinical Laboratory, Dr. Sardjito General Hospital. Results Of 36 children with ASD, 36.1% had hypovitaminosis D (<30 ng/mL) and 69.4% had severe ASD, based on the CARS-2 questionnaire (â‰¥37-60). Bivariate analysis revealed that children with hypovitaminosis D had more severe CARS-2 values â€‹â€‹(92.3%) compared to those with normal vitamin D levels (56.5%) (PR 1.633; 95%CI 1.10 to 2.42; P=0.031). Multivariate analysis with logistic regression revealed that hypovitaminosis D increased the risk of severe ASD (PR 1.65; 95%CI 1.06 to 2.56; P=0.037). However, other variables such as gender, parental education, attention deficit and hyperactivity disorder (ADHD), epilepsy, sleep disorders, pharmacotherapy and non-pharmacotherapy had no significant relationships with severe ASD. Conclusion Children with ASD and hypovitaminosis D have a 1.65 times higher risk of severe ASD compared to children with ASD and sufficient vitamin D levels. We recommend that children with ASD undergo serum 25(OH)D monitoring.

Perbedaan arus puncak ekspirasi antara anak asma dengan obesitas dan anak asma tanpa obesitas Nurul Hadi; Madarina Julia; Roni Naning
Jurnal Gizi Klinik Indonesia Vol 10, No 1 (2013): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.18839

Background: Obesity in children is associated with impairment of pulmonary function and increased risk of asthma. Obesity in asthmatic children may reduce lung function, that can be assessed by peak flow meter, a practical and an inexpensive tool.Objectives: To compare the peak expiratory flow (PEF) between obese and non-obese asthmatic children.Method: We conducted a cross sectional study in Yogyakarta during March 2010-September 2012. Fifty obese asthmatic patients and 50 non obese asthmatic control subjects participated in this study. Inclusion criteria were asthmatic patient, according to Pedoman Nasional Asma Anak (PNAA), and 6-18 years of age. Exclusion criteria were asthmatic attack, respiratory disease, heart disease and congenital chest malformation. Obesity is defined as body mass index (BMI) for age more than +3 SD WHO growth chart standards BMI for age 2007 z-score. Z-score is calculated with WHO AnthroPlus for Personal Computers. Data PEF is taken with electrical peak flow meter when the patient was not suffering from asthma attack. Normal PEF was defined as PEF ≥80% average (predicted) value for height.Results: The mean of age of asthmatic children in this study was 9.38 years and 9.50 years for non obese and obese respectively. The PFR was not different between obese asthmatic children and non obese asthmatic children (p=0,83). Pearson correlation of PFR and z-score BMI for age was positive weak correlation (r=0.12). There was significant difference of PFR between z-score BMI for age <3,20 and z-score BMI for age ≥3.20 (p=0.03). Significant difference of PFR also appears in duration of illness (p<0.001).Conclusion: There is no PFR difference between obese asthmatic children and non-obese asthmatic children. The difference of PFR emerges when statistic analysis performed using z-score BMI ≥3.20.

Computer Aided Classification of X-ray Images from Pediatric Pneumonia Subjects Collected in Developing Countries Yusuf Aziz Amrulloh; Bayu Dwi Prasetyo; Ummatul Khoiriyah; Hesti Gunarti; Dwikisworo Setyowireni; Rina Triasih; Roni Naning; Amalia Setyati
ELKHA : Jurnal Teknik Elektro Vol. 15 No.2 October 2023
Publisher : Faculty of Engineering, Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/elkha.v15i2.69981

Pneumonia is a lower tract respiratory infection due to bacteria or viruses. It is a severe disease in the pediatric population. Pneumonia is the leading cause of mortality in children under five years worldwide. One of the problems with pneumonia is the diagnosis, as the symptoms of pneumonia may overlap with other diseases, such as asthma and bronchiolitis. In this work, we propose to develop a method for classifying pneumonia and non-pneumonia using X-ray images. We collected 60 X-ray images from Dr. Sardjito Hospital, Yogyakarta, Indonesia, and the dataset from Kaggle. We processed these images through pre-processing algorithms to enhance the image quality, segmentation, white pixel computation, and classification. The novelty of our method is using the ratio of the white pixels from edge detection using the Canny algorithm with the white pixels from segmentation for classifying pneumonia/non-pneumonia. In the Kaggle dataset, our proposed method achieved an accuracy of 86.7%, a sensitivity of 100%, and a specificity of 85%. The classification using the dataset from Dr. Sardjito Hospital yields sensitivity, specificity, and accuracy of 80%, 60%, and 66.7%, respectively. Despite the low performance in the results, we proved our novel feature, ratio of white pixels, can be used to classify pneumonia/non-pneumonia. We also identified that the local dataset is essential in the algorithm development as it has a different quality from the dataset from modern countries. Further, our simple method can be developed further to support pneumonia diagnosis in resource-limited settings where the advanced computing devices or cloud connection are not available.

Co-Authors . Yustinah Amalia Setyati Azwar Aruf Bayu Dwi Prasetyo Carolina Kurniawan Dibyo Pramono Diyah Rakanita Undang Dwikisworo Setyowireni Hesti Gunarti Indah Kartika Murni Madarina Julia Madarina Julia Mei Neni Sitaresmi Nenny Sri Mulyani Ni Kadek Nira Noormanto Noormanto Nurul Hadi Nurul Hadi, Nurul Purnomo Suryantoro Rina Triasih Sasmito Nugroho Ummatul Khoiriyah Vita Susianawati Yusuf Aziz Amrulloh

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