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Hiromitsu Takayama
Faculty of Pharmaceutical Sciences, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba 263-8522
Astronomy Chemistry Earth & Planetary Sciences Mathematics Physics

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Artelastokromen Suatu Diprenilpiranoflavon dan B-Resorsilaldehid dari Kayu Batang Artocarpus Lanceifolius Didin Mujahidin; Sjamsul Arifin Achmad; Yana Maolana Syah; Euis Holisotan Hakim; Lukman Makmur; Norio Aimi; Mariko Kitajima; Hiromitsu Takayama; Rusjdi Tamin
Journal of Mathematical and Fundamental Sciences Vol. 32 No. 2 (2000)
Publisher : Institute for Research and Community Services (LPPM) ITB

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Abstrak. Dua senyawa, yaitu artelactokromen (1), suatu diprenil piranoflavon, dan B-resorsilaldehid (2) telah ditemukan untuk pertama kalinya pada kayu batang tumbuhan Artocarpus lanceifolius Roxb. (Moraceae), suatu tumbuhan langka yang endemic untuk Indonesia dan dikenal dengan nama Keledang. Struktur molekul kedua senyawa tersebut telah ditetapkan berdasarkan data fisika dan spektroskopi (MS, 1H dan 13C NMR). Baik artelastokromen (1) maupun B-resorsilaldehid (2) tidak terlalu toksik terhadap nauplii udang Artemia salina Leach., masing-masing dengan LC50 298,2 dan 79,7 ug/mL. Artelastochromene a Diprenylphyranoflavone and Î’-Resorcylaldehyde from the Wood Trunk of Artocarpus LanceifoliusAbstract. Two phenolic constituent, namely artelastochromene (1), a diprenyl pyranoflavone, and β-resorcylaldehyde (2) had been isolated from the wood trunk of Artocarpus lanceifolius Roxb. (Moraceae), an endemic species of Indonesia, locally known as Keledang. The structures of both compounds were elucidated based on physical and spectroscopic data (MS, 1H and 13C NMR). Both artelastochromene (1) and β-resorcylaldehyde (2) showed very slight toxic effect against shrimp nauplii Artemia salina Leach., LC50 298,2 and 79,7 μg/mL, respectively.
Artoindonesianin D: a New Bioactive Pyranoflavone Derivative and Chaplashin from Artocarpus Maingayi Euis Holisotan Hakim; Affrida Affrida; Eliza Eliza; Sjamsul Arifin Achmad; Lukman Makmur; Didin Mujahidin; Yana Maolana Syah; Norio Aimi; Mariko Kitajima; Hiromitsu Takayama
Journal of Mathematical and Fundamental Sciences Vol. 32 No. 1 (2000)
Publisher : Institute for Research and Community Services (LPPM) ITB

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Sari. Suatu senyawa baru flavonoid terisoprenilasi turunan piranoflavon, yakni 5-hidroksisiklomorusin yang diberi nama artoindonesianin D (1), dan suatu senyawa turunan oksepinoflavon, yakni chaplasin (2), telah ditemukan untuk pertama kalinya, masing-masing pada kulit akar dan kayu akar tumbuhan Artocarpus maingayi King (Moraceae). Tumbuhan langka ini berasal dari Sumatera Barat dan endemik untuk Indonesia, serta dikernal dengan nama daerah Cubadak Utan. Struktur molekul kedua senyawa tersebut telah ditetapkan berdasarkan data fisika dan spektroskopi (MS, 1H dan 13C NMR). Artoindonesianin D (1) dan chaplasin (2) bersifat toksik terhadap nauplii udang Artemia salina Leach. Artoindonesianin D: a New Bioactive Pyranoflavone Derivative and Chaplashin from Artocarpus MaingayiAbstract. A new isoprenylated flavonoid, a pyranoflavone derivative 5'-hydroxycyclomorusin named artoindonesianin D (1), and an oxepinoflavone derivative chaplashin (2) were isolated for the first time, respectively from the root bark and root trunk of Artocarpus maingayi King. (Moraceae). This plant is locally known as Cubadak Utan, a rare species found in West Sumatera and endemic to Indonesia. The structure of both compounds were elucidated based on physical and spectroscopical data (MS, 1H and 13C NMR). Artoindonesianin D (1) and chaplashin (2) showed toxic effect against shrimp nauplii Artemia salina Leach.
Senyawa Turunan Piranoflavon dan Furanodihidrobenzoxanton dari Artocarpus Ianceifolius Euis Holisotan Hakim; Asnizar Asnizar; Fera Kurniadewi; Tedi Abdul Ghofar; Sjamsul Arifin Achmad; Lukman Makmur; Didin Mujahidin; Norio Aimi; Mariko Kitajima; Hiromitsu Takayama; Rusjdi Tamin
Journal of Mathematical and Fundamental Sciences Vol. 31 No. 2 (1999)
Publisher : Institute for Research and Community Services (LPPM) ITB

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Sari. Dua senyawa turunan piranoflavon dan furanodihidrobenzosanton, masing-masing artelastin (1) dan sikloartobiloksanton (2), telah ditemukan masing-masing pada kayu dan kulit batang tumbuhan Artocarpus lanceifolius Roxb. (Moraceae), suatu tumbuhan langka yang endemik untuk Indonesia dan dikenal dengan nama Keledang. Struktur molekul kedua senyawa tersebut telah ditetapkan berdasarkan data fisika dan spektroskopi (MS, 1H dan 13C NMR). Artelastin (1) sangat menghambat transportasi asam amino leusin melalui membran usus ulat sutera Bontbyx mori, sedangkan sikloartobilosanton (2) menunjukkan toksisitas yang tinggi terhadap udang Artemia salina. Pyranoflavone and Furanodihydrobenzoxanthone Derivatives from Artocarpus IanceifoliusAbstract. Two pyranoflavone and furanodihydrobenzoxanthone derivatives, namely artelastin (1) and cycloartobiloxanthone (2), had been isolated respectivelfy from the wood and the tree bark of Artocarpus lanceifolius Roxb. (Moraceae), an endemic species of lndonesia, locally known as Keledang. The structures of both compounds were elucidated based on physical and spectroscopic data (MS, 1H and 13C NMR). Artelastin (1) strongly inhibited leucin amino acid transport in Bombyx mori midgut, while cycloartobiloxanthone (2) showed high toxicity against Artemia salina shrimp. Bagian ke-6 dari seri Ilmu Kimia Tumbuhan Moraceae Indonesia, untuk bagian ke-5 lihat Pustaka (8)
Artoindonesianin-E suatu senyawa baru turunan flavanon dari tumbuhan Artocarpus Champeden Euis Holisotan Hakim; Asep Aripin; Sjamsul Arifin Achmad; Norio Aimi; Mariko Kitajima; Lukman Makmur; Didin Mujahidin; Yana Maolana Syah; Hiromitsu Takayama
Journal of Mathematical and Fundamental Sciences Vol. 33 No. 3 (2001)
Publisher : Institute for Research and Community Services (LPPM) ITB

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Sari. Suatu senyawabaru turunan flavanon, yakni 5,7-dihidroksi-2',4',6'-trimetoksiflavanon yang diberi nama artoindonesianin-E(1 ), telah ditemukan untuk pertama kalinya bersama-samad engan artokarpin (2) dan heteroflavanon-A (3) pada ekstrak benzena kulit batang tumbuhan Artocarpus champeden Spreng (Moraceae), suatu tumbuhan yang endemik untuk Indonesia, serta dikenal dengan narna Cempedak. Struktur molekul senyawa tersebut telah ditetapkan berdasarkan data fisika dan spekroskopi (MS, 1H dan 13C NMR).Artoindonesianin-E a New Flavanone Derivative from Artocarpus ChampedenAbstract. A new flavanone derivative, 5,7-dihydroxy-2',4',6'-trimethoxyflavanone named artoindonesianin-E (1) had been isolated for the first time, together with artocarpin (2) and heteroflavanone-A (3) from benzene extract of the tree bark of Artocarpus champeden Spreng. (Moraceae), a species endemic to Indonesia and locally known as Cempedak. The structure of this compound was elucidated based on physical and spectroscopic data (MS, 1H and 13C NMR).
Co-Authors Affrida Affrida Asep Aripin Asnizar Asnizar Didin Mujahidin Didin Mujahidin Didin Mujahidin Didin Mujahidin Eliza Eliza Euis Holisotan Hakim Euis Holisotan Hakim Euis Holisotan Hakim Fera Kurniadewi Lukman Makmur Lukman Makmur Lukman Makmur Lukman Makmur Mariko Kitajima Norio Aimi Rusjdi Tamin Rusjdi Tamin Sjamsul Arifin Achmad Sjamsul Arifin Achmad Sjamsul Arifin Achmad Sjamsul Arifin Achmad Tedi Abdul Ghofar Yana Maolana Syah Yana Maolana Syah Yana Maolana Syah