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All Journal Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research Kreativitas Pada Pengabdian Masyarakat (Krepa)
Dwi Indira Setyorini
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Arts Biochemistry, Genetics & Molecular Biology Education Energy Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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The Role of Vascular Endothelial Growth Factorin Thrombocytosis in Colorectal Cancer Patients: The Role of VEGF in Thrombocytosis Subandrate Subandrate; Dwi Indira Setyorini; Mediarty Mediarty; Irsan Saleh
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 2 No. 2 (2018): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v2i2.45

Abstract

Backgorund: Colorectal cancer was included in a group of cancer with various complications. One complication that was often a cause of morbidity and mortality was thrombocytosis. In colorectal cancer, the incidence of thrombocytosis associated with the formation of blood vessels around the tumor or angiogenesis. Factors that played an important role in angiogenesis was vascular endothelial growth factor (VEGF). Methods: This study was an observational analytic research in colorectal cancer patients to determine the correlation levels of platelets and serum VEGF levels. A total of 33 patients with colorectal cancer at the Palembang Mohammad Hoesin Hospital be research subjects to examine the levels of platelets and levels of VEGF. The level of serum VEGF was performed using ELISA technique from SIGMA®. Results: The average level of the patient's platelets was281,090.9±105,860.8/mm3. In this study, two patients (6.06%) have thrombocytosis.The average serum levels of VEGF research subjects were 221.2 ± 152.8 pg/mL.Correlation test of levels of serum VEGF and platelets levels showed the value of p=0.040 (p> 0.05) and r = 0468. Conclusions: Thus, it can be concluded that in this research serum VEGF levels are almost always causes an increase in platelet levels in patients with colorectal cancer.
Korelasi antara indeks massa tubuh dan profil lipid pada remaja obesitas di kota Palembang Subandrate Subandrate; Sadakata Sinulingga; Eka Febri Zulissetiana; Susilawati Susilawati; Dwi Indira Setyorini; Ella Amalia
Majalah Kedokteran Andalas Vol 43, No 2 (2020): Online Mei 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v43.i2.p105-111.2020

Abstract

Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi  antara indeks massa tubuh  dan profil lipid pada remaja obesitas di Kota Palembang. Metode: Penelitian ini adalah penelitian analitik observasional dengan desain potong lintang terhadap 143 remaja di Kota Palembang. Indeks massa tubuh dihitung berdasarkan berat badan (kg) dan tinggi badan (m). Kadar profil lipid berupa kolesterol total, trigliserida, LDL-kolesterol dan HDL-kolesterol darah diperiksa menggunakan kit dari human® di Laboratorium Kimia Dasar Fakultas Kedokteran Universitas Sriwijaya. Analisis data menggunakan uji korelasi Pearson. Hasil: Dari penelitian ini didapatkan sekitar 29,4% remaja di Kota Palembang mengalami obesitas dan sekitar 17,5% remaja mengalami dislipidemia. Uji korelasi Pearson antara indeks massa tubuh dan profil lipid menunjukkan nilai p=0,093 r=0,141, p=0,002 r=0,260, p=0,983 r=0,002, dan p=0,256 r=0,096 masing-masing untuk kolesterol total, trigliserida, LDL-kolesterol dan HDL-kolesterol. Korelasi indeks massa tubuh dengan kadar kolesterol total, LDL-kolseterol dan HDL-kolesterol tidak bermakna (p>0,05). Namun, korelasi indeks massa tubuh dengan kadar trigliserida bermakna (p<0,05) dengan arah korelasi postif dan kekuatan lemah (r=0,2-0,4). Simpulan: Pada remaja, tidak ada korelasi indeks massa tubuh dengan kadar kolesterol total, LDL-kolseterol dan HDL-kolesterol. Terdapat korelasi positif antara indeks massa tubuh dan kadar trigliserida pada remaja. 
The Role of Vascular Endothelial Growth Factorin Thrombocytosis in Colorectal Cancer Patients: The Role of VEGF in Thrombocytosis Subandrate Subandrate; Dwi Indira Setyorini; Mediarty Mediarty; Irsan Saleh
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 2 No. 2 (2018): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v2i2.45

Abstract

Backgorund: Colorectal cancer was included in a group of cancer with various complications. One complication that was often a cause of morbidity and mortality was thrombocytosis. In colorectal cancer, the incidence of thrombocytosis associated with the formation of blood vessels around the tumor or angiogenesis. Factors that played an important role in angiogenesis was vascular endothelial growth factor (VEGF). Methods: This study was an observational analytic research in colorectal cancer patients to determine the correlation levels of platelets and serum VEGF levels. A total of 33 patients with colorectal cancer at the Palembang Mohammad Hoesin Hospital be research subjects to examine the levels of platelets and levels of VEGF. The level of serum VEGF was performed using ELISA technique from SIGMA®. Results: The average level of the patient's platelets was281,090.9±105,860.8/mm3. In this study, two patients (6.06%) have thrombocytosis.The average serum levels of VEGF research subjects were 221.2 ± 152.8 pg/mL.Correlation test of levels of serum VEGF and platelets levels showed the value of p=0.040 (p> 0.05) and r = 0468. Conclusions: Thus, it can be concluded that in this research serum VEGF levels are almost always causes an increase in platelet levels in patients with colorectal cancer.
EDUKASI PENYIMPANAN DAN PENYAJIAN ASI PERAH SEBAGAI UPAYA MENJAGA KANDUNGAN NUTRISI ASI Subandrate Subandrate; Ella Amalia; Dwi Indira Setyorini; Safyudin Safyudin
Kreativitas Pada Pengabdian Masyarakat (Krepa) Vol. 2 No. 3 (2024): Kreativitas Pada Pengabdian Masyarakat (Krepa)
Publisher : CV SWA Anugerah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.8765/krepa.v2i3.1947

Abstract

Exclusive breastfeeding is still not fully carried out by Indonesian mothers. The problem with breastfeeding is the lack of knowledge among mothers and working mothers. To promote exclusive breastfeeding again, educational programs can be carried out. Educational activities are carried out offline at the Prabumulih Mayor's Office Hall. Participants in this community service activity were PKK women from Prabumulih City, with a total of 54 people and ages ranging from 27 years to 71 years. The expert in this activity were dr. Ella Amalia, M.Kes, secretary of the South Sumatra Branch of the Association of Indonesian Breastfeeding Mothers (AIMI), and the national ASI counselor. She informed that breast milk contains sufficient nutrients for the growth and development of infants. Working mothers can continue to provide expressed breast milk (ASIP) to their babies. Giving ASIP to infants requires attention to how it is stored and served. Defrosting ASIP by gradually increasing the temperature, for example, from the freezer to the fridge and then to room temperature, is considered better than direct defrosting with hot water or a heater. Community service activities have been carried out well. This service can provide education to breastfeeding mothers regarding the proper storage and presentation of ASIP.
Co-Authors Eka Febri Zulissetiana Ella Amalia, Ella Irsan Saleh Mediarty Mediarty Sadakata Sinulingga Safyudin Subandrate Subandrate Subandrate Susilawati Susilawati