Abstrak Penelitian ini bertujuan untuk menganalisis pengaruh kepemimpinan dan kompetensi terhadap kinerja pengadaan barang dan jasa pemerintah di Direktorat Pencegahan dan Pengendalian Penyakit Menular Langsung Kementerian Kesehatan Republik Indonesia. Penelitian ini menggunakan pendekatan kuantitatif. Pengumpulan data dilakukan menggunakan membagikan kuesioner kepada 104 responden yang diambil secara sensus. Analisis data dilakukan dengan menggunakan SPSS. Hasil penelitian menemukan bahwa kepemimpinan dan kompetensi berpengaruh terhadap kinerja pengadaan barang dan jasa pemerintah di Direktorat Pencegahan dan Pengendalian Penyakit Menular Langsung Kementerian Kesehatan Republik Indonesia, baik secara parsial maupun secara simultan. Kata Kunci: Kepemimpinan, Kompetensi, Kinerja, Pengadaan Barang dan Jasa Pemerintah. Abstract This study aims to analyze the influence of leadership and competence on the performance of government procurement of goods and services in the Directorate of Prevention and Control of Direct Communicable Diseases of the Ministry of Health of the Republic of Indonesia. This study uses a quantitative approach. Data collection was carried out using questionnaires to 104 respondents taken by census. Data analysis was performed using SPSS. The results found that leadership and competence affect the performance of government procurement of goods and services in the Directorate of Prevention and Control of Direct Communicable Diseases of the Ministry of Health of the Republic of Indonesia, both partially and simultaneously. Keywords: Leadership, Competence, Performance, Procurement of Government Goods and Services.