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All Journal Borneo Journal of Medical Laboratory Technology
Muhammad Rizwan Nafarin
Universitas Muhammadiyah Palangkaraya
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology

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Rasio AST/ALT pada Laki-Laki Pengkonsumsi Alkohol di Jalan Mendawai Kota Palangka Raya Dwi Purbayanti; Muhammad Rizwan Nafarin
Borneo Journal of Medical Laboratory Technology Vol 1 No 2 (2019): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (160.122 KB) | DOI: 10.33084/bjmlt.v1i2.710

Abstract

Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) are enzymes predominantly found in hepatocytes, the increased activity in the serum shows liver damage. The AST / ALT ratio is used as a marker for alcoholic liver disease. This study aims to determine the effects of long-term alcohol consumption on the risk of alcoholic liver disease. This study was a descriptive study, involving 20 alcoholic drinkers aged 25-45 years, had consumed alcohol> 5 years and consumed alcohol every day. Our results showed a significant increase (p <0.05) in AST and ALT values based on age group, duration of consumption and dose. While the ratio of AST / ALT, a significant increase was found in the age group and period. In alcohol drinkers, the AST value is higher than ALT. The AST / ALT ratio for heavy drinkers is 1.64. Conclusion: Alcohol-consuming subjects in our study, especially heavy drinkers, were suspected of having a risk of alcoholic liver disease because most had an AST / ALT ratio > 1,5.
Co-Authors Dwi Purbayanti