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All Journal Medica Arteriana (Med-Art) Borneo Journal of Medical Laboratory Technology Jurnal Pengabdian Masyarakat Kedokteran
Andina Putri Aulia
Universitas Islam Sultan Agung
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Review: Effect of Red Cabbage Juice (Brassica oleracea var. Capitata f. Rubra) on SGPT Level Hesty Wahyuningsih; Andina Putri Aulia
Borneo Journal of Medical Laboratory Technology Vol 3 No 1 (2020): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v3i1.1791

Abstract

Red cabbage (Brassica oleracea var. Capitata f. Rubra) is a vegetable widely used in Indonesian cuisine. Red cabbage is rich in anthocyanins to reduce SGPT levels in drug-induced liver injury (DILI). This study aims to determine the effect of red cabbage juice on SGPT levels in acetaminophen-induced liver injury. In this post-test, only the control group study, male Wistar rats (300g), were randomly divided into 5 groups (K1-K2-K3-K4-K5). Acetaminophen was given to induce liver injury in rats. The rats were treated with the cabbage juice (at the dose of 0.5g/ml or 0.7g/ml or 0.9g/ ml. Data were analyzed using One way ANOVA and LSD post hoc test. Mean SGPT levels for K1, K2, K3, K4, K5 was 58.43 ± 7.18 UI / L, 71.20 ± 9.13 UI/L, 55.73 ± 9.51 UI / L, 72.80 ± 3.47 UI /L, 72.63 ± 3.01 UI /L, respectively. One way ANOVA resulted in p=0.00 (p <0.05). The post hoc LSD test showed significant differences (P <0.05) between all groups except between groups K1-K3, K2-K4, and K2-K5 (p> 0.05). Red cabbage juice can reduce SGPT in acetaminophen-induced liver injury in rats. The most effective dose was 0.5 g/ml.
Effect of Red Cabbage Juice as a Hepatoprotector on Liver Enzyme Levels Andina Putri Aulia; Hesty Wahyuningsih
Borneo Journal of Medical Laboratory Technology Vol 4 No 1 (2021): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v4i1.2957

Abstract

Background: Anthocyanin-rich red cabbage is known to reduce hepatic enzymes levels such as SGPT, SGOT, ALP, and GGT in drug-induced liver injury (DILI). Objective: This study aimed to determine the effect of red cabbage juice on SGOT, ALP, and GGT levels in acetaminophen-induced liver injury in rats.Methods: This was an experimental study using a post-test-only control group design. Thirty male Wistar rats were randomly divided into 5 groups. K1 was the negative control. K2, K3, K4, and K5 were pretreated with 300 mg acetaminophen. K3, K4, and K5 were treated with 0.5 g/ml of red cabbage juice, 0.7 g/ml of red cabbage juice, and 0.9 g/ml of red cabbage juice respectively. Data were analyzed using one-way ANOVA and post hoc LSD (p<0.05). Results: There was no significant difference in SGOT and GGT levels among the groups p=0.271(p>0.05) and p=0.053 (p>0.05) respectively. Whereas ALP levels showed significant differences among the groups p=0.000 (p<0,05) respectively. Conclusion: The administration of red cabbage in any dose had no effect on SGOT and GGT levels in acetaminophen-induced liver injury in rats whereas in ALP, the most effective dose to cause an effect is 0.5 g/ml.
Hubungan Antara Neutrophil Lymphocyte Ratio dan Absolute Lymphocyte Count dengan Mortalitas Pasien Covid-19 (Studi Observasional Analitik pada Pasien COVID-19 yang Dirawat Inap di Rumah Sakit Islam Sultan Agung Semarang Periode Mei–Agustus 2021) Danis Pertiwi; Andina Putri Aulia; Rahayu Rahayu
Medica Arteriana (Med-Art) Vol 4, No 1 (2022): Juni 2022
Publisher : University of Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/medart.4.1.2022.32-38

Abstract

Latar Belakang: SARS-CoV-2 merupakan virus penyebab COVID-19. Peran penanda inflamasi cukup besar dalam menilai perjalanan penyakit COVID-19, salah satunya Neutrophil Lymphocyte Ratio (NLR) dan Acute Lymphosit Account (ALC) yang menggabungkan neutrofil sebagai komponen inflamasi aktif serta limfosit sebagai regulator dan komponen protektif dalam satu kesatuan parameter. Penelitian mengenai hubungan antara NLR dan ALC dengan mortalitas pasien rawat inap COVID-19 masih terbatas. Oleh karena itu, penelitian ini dilakukan untuk mengetahui hubungan antara NLR dan ALC dengan mortalitas pasien COVID-19 yang dirawat inap di RSI Sultan Agung Semarang.Metode: Penelitian observasional analitik dengan desain kohort retrospektif dengan subjek sebanyak 153 orang pasien COVID-19 yang dirawat inap di RSI Sultan Agung Semarang pada bulan Mei - Agustus 2021. Data diperoleh melalui pencatatan dari rekam medis. Data berskala kategorik dan diuji dengan metode korelasi spearman menggunakan aplikasi SPSS versi 22.Hasil: Didapatkan rerata nilai NLR pasien COVID19 yang sembuh adalah 3,17 dan yang meninggal adalah 14,4. Rerata nilai ALC pasien COVID-19 di RSI Sultan Agung Semarang yang sembuh adalah 2200 /µL dan yang meninggal 1158 /µL. Hasil analisis menunjukkan nilai p = 0,001 dengan nilai r = 0,59 untuk hubungan antara nilai NLR dengan mortalitas pasien COVID dan r = 0,261 untuk hubungan antara nilai ALC dengan mortalitas pasien COVID-19.Kesimpulan: Penelitian ini menunjukan terdapat hubungan bermakna antara nilai NLR dan ALC dengan mortalitas pasien rawat inap COVID-19 di RSI Sultan Agung Semarang. 
Pengaruh Penyuluhan dan Pelatihan Skill Moulage terhadap Pengetahuan Teknik Moulage pada Pasien Simulasi OSCE Afridatul Luailiyah; Andina Putri Aulia
Jurnal ABDIMAS-KU: Jurnal Pengabdian Masyarakat Kedokteran Vol 1, No 2 (2022): Mei
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (336.985 KB) | DOI: 10.30659/abdimasku.1.2.49-56

Abstract

Moulage merupakan teknik makeup effect untuk menciptakan keadaan yang mendekati nyata pada setting ujian OSCE di bidang kesehatan. Tujuan kegiatan pengabdian ini untuk mengetahui pengaruh penyuluhan dan pelatihan skill teknik moulage terhadap pengetahuan teknik moulage pada pasien simulasi OSCE. Desain pra-eksperimen dengan rancangan perlakuan ulang (one group pre and postest design) yaitu dengan memberikan penyuluhan, dan pelatihan moulage luka lebam. Peserta adalah pasien simulasi OSCE yang berjumlah 20. Peserta diberikan pretes dan postes pada akhir kegiatan sebagai evaluasi terhadap kegiatan yang dilaksanakan. Skor pengetahuan sebelum dan sesudah kegiatan dibandingkan. Data yang terkumpul dianalisis menggunakan uji Wilcoxon. Rerata skor pengetahuan sebelum kegiatan adalah 6,1 dan sesudah kegiatan 8,15 dengan hasil analisis diperoleh nilai p=0,00. Akhir kata, penyuluhan dan pelatihan teknik moulage berpengaruh terhadap peningkatan pengetahuan pasien simulasi.Moulage is a makeup effect technique to create a near real situation in the OSCE exam setting in the health sector. The purpose of this activity is to determine the effect of counseling and training on moulage technique skills on the OSCE simulation. The pre-experimental design was redesigned (one group pre and posttest design), namely by providing counseling, and training on bruising moulage. Participants are OSCE simulation returning 20. Participants are given a pretest and posttest at the end of the activity as an evaluation of the activities carried out. Knowledge scores before and before the activity were compared. The data collected were analyzed using the Wilcoxon test. The mean score of knowledge before the activity was 6.1 and before the activity was 8.15 the results of the analysis obtained a p value = 0.00. Counseling and training on moulage techniques have an effect on increasing knowledge of simulated patients.
Co-Authors Afridatul Luailiyah Danis Pertiwi Hesty Wahyuningsih Rahayu Rahayu