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All Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH

Tamara Audrey Kadarusman

Universitas Airlangga

Author-ID : 3412364

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Analgesic Drug Use for Carpal Tunnel Syndrome Tamara Audrey Kadarusman; Hanik Badriyah Hidayati; Paulus Sugianto
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Carpal tunnel syndrome (CTS) is a group of neuropathic symptoms regarding to the compression of median nerve which passing through carpal tunnel. There has been a great number of prevalence of CTS in Indonesia, which leads to decreasing quality of life, lack of work productivity, and increasing health cost. Analgesic treatments have been drug of choice for carpal tunnel syndrome for years. However, the effectiveness of the drug and the risk of adverse effect of drugs have always been an issue for analgesic use. An observational study on profile of analgesic drugs administration for carpal tunnel syndrome patients in Dr. Soetomo General Hospital SurabayaMethod: A descriptive observational retrospective study has been conducted to observe the profile of analgesic drugs administration, including type and dosage of drugs, classification of drugs, drugs administration route, early and advanced type of analgesics, and duration of analgesic administration. Sociodemographic data and clinical characteristics (main symptoms) of carpal tunnel syndrome patients are also included in this study.Results: Out of 202 subjects of this study, most patients are women (84,16%), the group age of 50-59 to years old, and the most frequent job is household wife (43,56%). The most common analgesic drugs used for carpal tunnel syndrome patients is 50 mg sodium diclofenac for 78 patients (38.61%). All of those subjects are administered with oral analgesic (100%). 185 patients (91.59%) are administered with analgesic combinations. The duration of analgesic usage are 7 days as an early analgesic in 82 patients (40.59%).Conclusion: CTS is a syndrome due to median nerve compression of the hand, Women, household wife, and age of 50-59 years old are found to be vulnerable to this syndrome. Analgesic drugs mostly used is 50 mg natrium diclofenac, orally, combined, with the period of 7 days for early medication

LITERATURE REVIEW: SENSITIVITY AND SPECIFICITY OF VDRL AND RPR AS SCREENING TESTS OF SYPHILIS IN PREGNANT WOMEN Tamara Audrey Kadarusman; Sacharissa Zerlina Tsarwah Thirafi; Niki Kusuma Bangsa; Rufina Adelia Widyatama; Lutfi Dewanda Nugroho; Prima Ardiansah Surya; Pudji Lestari
Journal of Community Medicine and Public Health Research Vol. 2 No. 2 (2021): Journal of Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Early detection of syphilis, especially during pregnancy, is important to prevent comorbidities for the mother and the baby. This study aims to determine whether VDRL is more sensitive and specific than RPR as a diagnostic screening test for syphilis infection in pregnant women. Literature searches for relevant articles were conducted in PubMed, Cochrane, and Proquest using the keywords "VDRL AND RPR AND pregnancy AND syphilis". From the search results, we found 7 articles in Pubmed, 2.290 articles in Proquest, and no relevant articles were found in Cochrane. Title and abstracts were screened for their conformity with the case and clinical questions that had been made. Selected articles were then critically appraised. The results of the study in selected articles indicated that VDRL and RPR showed a false positives rate of 10.5% and 9.6%, respectively. The sensitivity and specificity of VDRL were 71.6% and 89.5%, and those of RPR were 73.5% and 90.5%. VDRL and RPR have a moderate agreement with the TPHA (kappa = 0.6). From these studies it can be concluded that VDRL is not more sensitive and specific than RPR, implying that RPR is a better diagnostic screening test for syphilis infection in pregnant women than VDRL.

Co-Authors Hanik Badriyah Hidayati, Hanik Badriyah Lutfi Dewanda Nugroho Niki Kusuma Bangsa Paulus Sugianto Prima Ardiansah Surya Pudji Lestari Rufina Adelia Widyatama Sacharissa Zerlina Tsarwah Thirafi

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