Evert D.C. Poetiray
Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta 10430

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A clinical study on skin cancer in Indonesian patients Hamzah, Mochtar; Ichihashi, Masamitsu; Cipto, Herman; Poetiray, Evert D.C.; Mukhtar, Arman; Kanoko, Mpu; Tjarta, Achmad; Ueda, Masato; Cornain, Santoso; Budiningsih, Setyawati; Prihartono, Joedo; ohno, Yoshiyuki; Munakata, Nobuo
Medical Journal of Indonesia Vol 9, No 2 (2000): April-June (Special Issue: Skin Cancer)
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (608.21 KB) | DOI: 10.13181/mji.v9i2.640

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Breast-conserving treatment versus mastectomy in T1-2N0 breast cancer: which one is better for Indonesian women? Nugroho, Rafiq S.; Soediro, Ratnawati; Siregar, Nuryati C.; Djoerban, Zubairi; Poetiray, Evert D.C.; Gondhowiardjo, Soehartati
Medical Journal of Indonesia Vol 21, No 4 (2012): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.811 KB) | DOI: 10.13181/mji.v21i4.508

Abstract

Background: This study aimed to compare the treatment outcomes between the use of breast-conserving treatment (BCT) and mastectomy for T1-2N0 breast cancer patients.Methods: This study retrospectively reviewed T1-2N0 breast cancer patients who received treatment between January 2001 and December 2010 at Department of Radiotherapy Cipto Mangunkusumo Hospital and Jakarta Breast Center. The endpoints of this study were overall survival (OS), local  recurrence (LR), contra-lateral breast cancer (CBC), distant metastasis (DM), and disease-free survival (DFS).Results: Among the 262 eligible patients, 200 (76.3%) patients underwent BCT while 62 (23.7%) patients underwent mastectomy. There were no differences between BCT and mastectomy groups in 5-Y OS (88.2% vs 86.7%, p = 0,743), LR (7.4% vs 2.7%, p = 0.85), CBC (3.4% vs 5.3%, p = 0.906), DM (17.7% vs 37.7%, p = 0.212), and DFS (78.5% vs 60.7%, p = 0.163). In multivariate analysis, grade 3 was associated with worse OS (HR 2.79; 95% CI 1.08 – 7.21, p = 0.03) and DFS (HR 2.32; 95% CI 1.06 – 5.06). Premenopausal women were associated with decreased risk of DM (HR 0.37; 95% CI 0.17 – 0.80) and DFS (HR 0.38; 95% CI 0.19 – 0.78).Conclusion: BCT and mastectomy showed similar outcome in terms of OS, LR, CBC, DM, and DFS. (Med J Indones. 2012;21:220-4)Keywords: Breast-conserving treatment, mastectomy, outcomes