Garuda - Garba Rujukan Digital

Anna P. Roswiem

Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Author-ID : 3460216

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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1

PENGARUH KOMBINASI EKSTRAK ETANOL KULIT PUTIH BUAH SEMANGKA (CITRULLUS LANATUS (THUNB.)) DAN AIR BONGGOL PISANG KEPOK (MUSA ACUMINATA X MUSA BALBISIANA (ABB GROUP)) TERHADAP PERTUMBUHAN RAMBUT TIKUS PUTIH JANTAN M. Ikhwan Setiawan; Anna P. Roswiem; Ika Wahyu Pertiwi
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 2 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

White skin of watermelon and the liquid of kepok banana tree trunk empirically widely used as hair growth, In addition ethanol extract white skin of watermelon and the liquid of kepok banana tree trunk has also been scientifically proven able to accelerate the growth hair of the rat. However the research activity of the combination of the two against the hair growth has never done. The purpose of this research is to know the combination of both these extracts which can give of the most activity is good for hair growth. Ethanol extract of white skin of watermelon extraction is done by of maceration using a solvent of ethanol 70 %, as for getting the test sample is liquid of kepok banana tree trunk done by cutting down banana tree trunk approximately 50 cm above the ground surface then the stem of banana leaf his satin-the core then covered with plastic and silenced for one night. The results showed that the combination of liquid of kepok banana tree trunk and Ethanol extract white skin of watermelon (2:1) have a long hair growth activity higher than the positive control (Minoxidil), While hair growth activity of weights lower than the positive control (Minoxidil)

AKTIVITAS INHIBISI α-GLUKOSIDASE DARI EKSTRAK AIR DAN ETANOL DAUN SIMPUR AIR (Dillenia suffruticosa (Griff.) Martelli) Sitaresmi Yuningtyas; Anna P. Roswiem; Erfina
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Diabetes mellitus is a disorder of carbohydrate metabolism which characterized by hyperglycemia conditions. One of the mechanism from oral hypoglycemic drug is inhibition of α-glucosidase activity. Dillenia suffruticosa (Griff.) Martelli, known as "simpur air" has been used to treat diabetes mellitus. This study aims to determine the inhibition activity of α-glucosidase enzyme from water and ethanol extract simpur air leaves. Simpur air leaves extracted with water and ethanol 70% using maceration method. Parameter evaluated in this research were phytocemical screening and alpha glucosidase inhibiting (AGI) activity. The results showed that the active compounds in water and ethanol extracts were flavonoids, saponins and tannins. AGI activity in water extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 1.49%, 2.76% and 3.91%, respectively. AGI activity in ethanol extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 92.10%, 98.10% and 118.30%, respectively. While the AGI activity from glucobay were 99.50%. The optimum of AGI activity was in 1.5% ethanol extract. This AGI acivity which was not significantly different (α<0.05) from the 1% glucobay.

Potensi Ekstrak Daun Kacang Panjang (Vigna unguiculata (L.) Walp.) dan Daun Mangkokan Polyscias scutellaria (Burm.f.) Fosberg) Serta Kombinasinya terhadap Pertumbuhan Rambut Pada Tikus Jantan Galur Sprague Dawley Triyani Sumiati; Anna P. Roswiem; Ayu Kusuma Wardhani
JURNAL KATALISATOR Vol. 7 No. 2 (2022): jurnal Katalisator Volume 7 No 2, Oktober 2022
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Daun kacang panjang (Vigna unguiculata (L) Walp.) dan Daun mangkokan (Polyscias scutellaria (Burm.f.) Fosberg) secara empiris mempunyai khasiat untuk pertumbuhan rambut dantelah terbukti secara ilmiah mampu mempercepat pertumbuhan rambut. Aktivitasnya setara dengan hair tonic yang terdapat di pasaran. Uji aktivitas kombinasi kedua ekstrak tersebut terhadap pertumbuhan rambut belum pernah dilakukan. Daun kacang panjang dan daun mangkokan masing-masing diekstraksi dengan etanol 70% menggunakan metode maserasi. Sebanyak 11 kelompok uji disiapkan untuk penentuan aktivitas pertumbuhan rambut pada berbagai konsentrasi, kelompok kontrol negatif dan kontrol positif. Setiap kelompok terdiri atas 3 ekor tikus putih jantan. Masing-masing tikus dicukur bulu pada bagian punggungnya hingga bersih, kemudian diberikan ekstrak uji dengan cara pengolesan pada daerah punggung yang dilakukan sebanyak 2 kali sehari dengan volume sebanyak 1 ml. Pengamatan panjang rambut dilakukan pada hari ke 7, 14 dan 21. Tujuan penelitian ini untuk mengetahui kombinasi ekstrak daun kacang panjang dan daun mangkokan yang dapat memberikan aktivitas paling baik untuk menumbuhkan rambut. Berdasarkan hasil penelitian diperoleh bahwa ekstrak daun kacang panjang 10% dan ekstrak daun mangkokan 15% memberikan hasil pertumbuhan rambut yang maksimal. Setelah waktu 21 hari diperoleh hasil pertumbuhan rambut sebesar 1,97 cm dengan bobot rambut seberat 0,4 gram untuk ekstrak daun kacang panjang 10% dan pertumbuhan rambut sebesar 2,08 cm dengan bobot rambut seberat 0,41 gram untuk ekstrak daun mangkokan 15%. Pada penelitian kombinasi ekstrak daun kacang panjang dan ekstrak daun mangkokan dengan konsentrasi (1:1) memberikan hasil pertumbuhan rambut sebesar 2,65 cm dan bobot rambut sebesar 0,58 gram. Berdasarkan hasil pengukuran bobot rambut dan pertumbuhan rambut, dapat disimpulkan bahwa kombinasi ekstrak daun kacang panjang : ekstrak daun mangkokan (1:1) memberikan hasil yang lebih baik dibandingkan dengan kontrol negatif tetapi tidak lebih baik dibandingkan dengan kontrol positif.

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