Garuda - Garba Rujukan Digital

AKTIVITAS INHIBISI ENZIM α-GLUKOSIDASE EKSTRAK AIR DAN ETANOL UMBI LAPIS BAWANG MERAH (Allium ascalonicum) Yuningtyas, Sitaresmi; Setiawati Artianti, Dian
FITOFARMAKA | Jurnal Ilmiah Farmasi Vol 5, No 1 (2015): FITOFARMAKA
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.493 KB)

Umbi lapis bawang merah (Allium ascalonicum) mempunyai potensi sebagaianalgesik, antiinflamasi, antimikobakterial, antifungi, dan antikanker. Namun mekanismeantidiabetes pada tanaman ini belum ditentukan. Salah satu varietas bawang merah diIndonesia adalah varietas Bima Brebes. Penelitian ini dilakukan untuk menguji potensiekstrak air dan etanol umbi lapis A. ascalonicum pada konsentrasi 1% sebagai inhibitor enzimα-glukosidase dan dibandingkan aktivitasnya dengan akarbosa 1% sebagai kontrol positif.Umbi lapis A. ascalonicum diekstraksi dengan menggunakan metode maserasi. Ekstrak airdan etanol dianalisis kandungan fitokimia dan daya inhibisinya terhadap enzim α-glukosidasesecara metode in vitro. Aktivitas α-glukosidase ditentukan dengan mengukur produk pnitrofenol yang dihasilkan dari reaksi enzim dan substrat p-nitrofenil-α-D-glukopiranosida (pNPG) menggunakan microplate absorbance reader pada panjang gelombang 410 nm. Hasiluji fitokimia menunjukkan bahwa ekstrak air umbi lapis A. ascalonicum mengandung flavonoid dan tanin. Selain itu, ekstrak etanol 96% dan ekstrak etanol 70% umbi lapis A. ascalonicum mengandung flavonoid, tanin, dan saponin. Ekstrak air, etanol 70%, etanol 96%umbi lapis A. ascalonicum pada konsentrasi 1% (b/v) dan akarbosa 1% dapat menginhibisiaktivitas enzim α-glukosidase berturut-turut sebesar 11,75%, 4,48%, 20,92%, dan 99,37%.Hasil aktivitas inhibisi ketiga ekstrak ini berbeda nyata (p < 0,05) dengan daya inhibisiakarbosa 1%. Hal ini mengindikasikan bahwa ekstrak air dan etanol umbi lapis A.ascalonicum berperan sebagai inhibitor enzim α-glukosidase.

AKTIVITAS ANTIHIPERKOLESTEROLEMIA DARI YOGHURT UMBI GARUT (Maranta arundinacea Linn) DENGAN PERBEDAAN FORMULASI KULTUR BAKTERI (Antihypercholesterolemia Activity from Arrowroot (M. arundinacea Linn) Yoghurt with Different Bacterial Culture Formulation) Sitaresmi Yuningtyas; Anggraena Roesmiena Waty; Devi Ratnasari
Biopropal Industri Vol 12, No 2 (2021)
Publisher : Balai Riset dan Standardisasi Industri Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36974/jbi.v12i2.6937

Hypercholesterolaemia is one of the factors causing cardiovascular disease. An alternative to prevent hypercholesterolemia is by consuming arrowroot yoghurt which has ability as hypocholesterolemic probiotic. Lactobacillus plantarum and Lactobacillus fermentum is known to have hypocholesterolemic potency. The aim of this research is to get the appropriate formulation of the culture to produce arrowroot yoghurt which can decrease total cholesterol level. Arrowroot is fermented using different lactic acid bacteria formula, comprising A (Lactobacillus plantarum : Lactobacillus fermentum), B (Lactobacillus plantarum), and C (Lactobacillus fermentum). Arrowroot yoghurt then evaluated with total of lactic acid, pH, lactic acid bacteria, organoleptic, and in vivo total cholesterol. The results showed that the best formula of arrowroot yoghurt using C culture based on total lactic acid, pH parameter, and total lactic acid bacteria. After the total cholesterol test, the results obtained that arrowroot yoghurt which fermented by Lactobacillus fermentum and positive control (simvastatin 0,18 mg/200 g body weight) can reduce total cholesterol levels with a decrease percentage of 30.36% and 27.13%. Therefore, arrowroot yoghurt which fermented by Lactobacillus fermentum had antihypercholesterolemic potency. Keywords: antihypercholesterolemia, arrowroot yoghurt, fermentation, probiotic bacteriaABSTRAKSalah satu faktor penyebab penyakit kardiovaskular adalah hiperkolesterolemia. Altenatif untuk mencegah hiperkolesterolemia adalah mengonsumsi yoghurt umbi garut probiotik hipokolesterolemik. Salah satu probiotik yang mempunyai potensi hipokolesterolemik adalah Lactobacillus plantarum dan Lactobacillus fermentum. Tujuan penelitian ini menentukan formulasi kultur yang tepat pada produksi bahan minuman probiotik dari umbi tanaman garut yang memiliki aktivitas menurunkan kadar kolesterol darah. Umbi garut difermentasi menggunakan formulasi kultur yang berbeda, terdiri dari A (Lactobacillus plantarum: Lactobacillus fermentum), B (Lactobacillus plantarum), dan C (Lactobacillus fermentum). Yoghurt umbi garut dievaluasi total asam laktat, pH, total bakteri asam laktat, organoleptik, dan diuji penurunan kadar kolesterol total secara in vivo. Formula yoghurt umbi garut terbaik menggunakan kultur C (Lactobacillus fermentum) berdasarkan parameter nilai total asam laktat, pH, dan total bakteri asam laktat. Setelah dilakukan uji penurunan kadar kolesterol total, maka yoghurt umbi garut yang difermentasi oleh Lactobacillus fermentum dan kontrol positif (simvastatin 0,18 mg/200 g bobot badan) dapat menurunkan kadar kolesterol total dengan persentase penurunan sebesar 30,36% dan 27,13%. Oleh karena itu, yoghurt umbi garut yang difermentasi oleh Lactobacillus fermentum berpotensi sebagai agen antihiperkolesterolemia.Kata kunci: antihiperkolesterolemia, bakteri probiotik, fermentasi, yoghurt umbi garut

SITOTOKSISITAS KOMBINASI EKSTRAK DAUN PETAI CINA DAN KULIT JENGKOL TERHADAP SEL KANKER PAYUDARA DAN SERVIKS (Cytotoxicity of Petai Cina Leaves and Jengkol Pods Combinations Against Breast Cancer Cells and Cervix) Harry Noviardi; Sitaresmi Yuningtyas; Dwi Suwarni
Biopropal Industri Vol 10, No 2 (2019)
Publisher : Balai Riset dan Standardisasi Industri Pontianak

Petai cina (Leucaena leucocephala (Lam.) De Wit) and jengkol (Archidendron jiringa (Jack) I.C.Nielsen) are leguminous plants that contain alkaloids, flavonoids, saponins, tannins and triterpenoids which potential to be anticancer. This study aimed to determine the synergic effect of petai cina leaves extract and jengkol pods combination based on its cytotoxicity value. The extraction used maceration method with 70% ethanol solvent. Comparison of the combination of petai cina leaves extract and jengkol pods were 1:0, 0:1, 1:1, 1:3, 1:5, 1:7 and 1:9. The cytotoxicity method used MTT assay with MCF-7 breast cancer cell culture and cervical HeLa. Inhibition valueconcentration (IC50) used as parameter. The combination with ratio 1:0, 0:1, 1:1, 1:3, 1:5, 1:7 and 1:9 showed cytotoxicity activity against MCF-7 cells with IC50 values respectively 102.56; 51.76; 37.35; 28.57; 11.69; 7.5 and 1.92 µg/mL while on HeLa cells 137.65; 39.62; 20.91; 14.46; 9.34; 7.28 and 1.86 µg/mL. Based on the National Cancer Institute (NCI), all comparisons classified as potential cytotoxicity except ratio1: 1 on MCF-7 cancer cells which considered as moderate since IC50 values were more than 30 µg/mL.Keywords: cytotoxicity, HeLa, jengkol pods, petai cina leaves, MCF-7ABSTRAKPetai cina (Leucaena leucocephala (Lam.) de Wit) dan jengkol (Archidendron jiringa (Jack) I.C.Nielsen) merupakan tumbuhan suku polong-polongan yang mengandung senyawa bahan alam seperti alkaloid, flavonoid, saponin, tanin dan triterpenoid. Senyawa bahan alam tersebut berpotensi sebagai antikanker. Kombinasi ekstrak bahan alam memiliki kelebihan terkait sinergisitas dibandingkan dengan ekstrak tunggal. Uji sitotoksisitas digunakan untuk mendeteksi potensi senyawa antikanker. Tujuan penelitian ini adalah untuk menentukan efek sinergis dari kombinasi ekstrak daun petai cina dan kulit jengkol berdasarkan pada nilai sitotoksisitasnya. Proses ekstraksi menggunakan metode maserasi dengan pelarut etanol 70%. Perbandingan kombinasi ekstrak daun petai cina dan kulit jengkol yang digunakan secara berturut-turut yaitu 1:0, 0:1, 1:1, 1:3, 1:5, 1:7 dan 1:9. Metode sitotoksisitas yang digunakan adalah MTT assay dengan kultur sel kanker payudara MCF-7 dan serviks HeLa. Parameter yang diukur adalah nilai inhibition concentration (IC50). Kombinasi ekstrak daun petai cina dan kulit jengkol dengan perbandingan 1:0, 0:1, 1:1, 1:3, 1:5, 1:7 dan 1:9 menunjukkan aktivitas sitotoksisitas terhadap sel MCF-7 dengan nilai IC50 secara berturut-turut sebesar 102,56; 51,76; 37,35; 28,57; 11,69; 7,5 dan 1,92 µg/mL sedangkan pada sel HeLa 137,65; 39,62; 20,91; 14,46; 9,34; 7,28 dan 1,86 µg/mL. Berdasarkan kriteria sitotoksisitas National Cancer Institute (NCI) semua perbandingan termasuk dalam kategori sitotoksisitas potensial, kecuali perbandingan 1:1 pada sel kanker MCF-7 termasuk dalam kategori sitotoksisitas sedang karena nilai IC50 lebih dari 30 µg/mL. Oleh sebab itu, kombinasi ekstrak daun petai cina dan kulit jengkol dapat digunakan sebagai agen antikanker yang memberikan efek sinergis lebih baik dari pada ekstrak tunggal.Kata kunci: daun petai cina, HeLa, kulit jengkol, MCF-7, sitotoksisitas

OPTIMASI WAKTU INKUBASI PRODUKSI BAHAN MINUMAN PROBIOTIK DARI UMBI GARUT (Maranta arundinacea L.) OLEH Lactobacillus fermentum SEBAGAI ANTIHIPERKOLESTEROLEMIA Harry Noviardi; Sitaresmi Yuningtyas; Vira Yuniar
Biopropal Industri Vol 11, No 1 (2020)
Publisher : Balai Riset dan Standardisasi Industri Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36974/jbi.v11i1.5846

Arrowroot tuber is one of the potential plants that has a high nutritional content so it can be the source of nutrition for the growth of Lactobacillus fermentum bacteria for probiotic drink production. Arrowroot fermentation with L. fermentum is also known potentially reduce cholesterol level. The probiotics have the ability to absorb a number of cholesterol into cells. This research aimed to determine the optimum incubation time of the production of arrowroot tubers with antihypercholesterolemia activity for pribiotic drink. Arrowroot tuber fermentation was carried out using L. fermentum culture with varying incubation times of 4, 8 and 12 hours. The fermentation results were evaluated organoleptically (color, aroma, texture and taste), pH, total lactic acid, total lactic acid bacteria and alcohol content. In addition, anylisis of total cholesterol levels by in vivo were also tested. The decreasing of total cholesterol level by the fermented tuber with incubation time variations of 4, 8 and 12 hours, respectively, by 15.14%, 16.96% and 28.56%. The results showed that the highest reduction percentage of total cholesterol level is 12 hours incubation time with pH value of 5.25, total lactic acid bacteria 6.4 x 108CFU/mL. The total value of acquired lactic acid bacteria meets the standard for probiotic product. This indicates that the optimum incubation time for the production of probiotic arrowroot tubers as antihypercholesterolemia is 12 hours.Keywords: antihypercholesterolemic, arrowroot tuber, Lactobacillus fermentum, probioticABSTRAKUmbi garut merupakan salah satu tanaman potensial yang memiliki kandungan gizi tinggi sehingga dapat dijadikan sumber nutrisi bagi pertumbuhan bakteri Lactobacillus fermentum untuk pembuatan minuman probiotik. Fermentasi umbi garut dengan L. fermentum tersebut juga diketahui memiliki potensi untuk menurunkan kadar kolesterol. Hal ini disebabkan oleh kemampuan probiotik menyerap sejumlah kolesterol ke dalam sel. Penelitian ini bertujuan untuk menentukan waktu inkubasi optimum produksi bahan minuman probiotik dari umbi garut yang mempunyai aktivitas antihiperkolesterolemia. Fermentasi umbi garut dilakukan menggunakan kultur L. fermentum dengan variasi waktu inkubasi, yaitu 4, 8 dan 12 jam. Hasil fermentasi dievaluasi organoleptik (warna, aroma, tekstur dan rasa), pH, total asam laktat, total bakteri asam laktat dan kadar alkohol. Selain itu, dilakukan juga analisis penurunan kadar kolesterol total secara in vivo. Nilai persentase penurunan kadar kolesterol total oleh hasil fementasi umbi garut dengan variasi waktu inkubasi 4, 8 dan 12 jam secara berturut-turut sebesar 15,14%, 16,96% dan 28,56%. Hasil fermentasi umbi garut dengan nilai persentase penurunan kadar kolesterol total tertinggi adalah waktu inkubasi 12 jam dengan nilai pH 5,25; total asam laktat 1,56%, total bakteri asam laktat 6,4 x 108 CFU/mL. Nilai total bakteri asam laktat yang diperoleh memenuhi standar untuk produk probiotik. Oleh sebab itu, waktu inkubasi optimum produksi umbi garut probiotik sebagai antihiperkolesterolemia berada pada waktu 12 jam.Kata kunci: antihiperkolesterolemia, Lactobacillus fermentum, probiotik, umbi garut

AKTIVITAS INHIBISI α-GLUKOSIDASE DARI EKSTRAK AIR DAN ETANOL DAUN SIMPUR AIR (Dillenia suffruticosa (Griff.) Martelli) Sitaresmi Yuningtyas; Anna P. Roswiem; Erfina
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Diabetes mellitus is a disorder of carbohydrate metabolism which characterized by hyperglycemia conditions. One of the mechanism from oral hypoglycemic drug is inhibition of α-glucosidase activity. Dillenia suffruticosa (Griff.) Martelli, known as "simpur air" has been used to treat diabetes mellitus. This study aims to determine the inhibition activity of α-glucosidase enzyme from water and ethanol extract simpur air leaves. Simpur air leaves extracted with water and ethanol 70% using maceration method. Parameter evaluated in this research were phytocemical screening and alpha glucosidase inhibiting (AGI) activity. The results showed that the active compounds in water and ethanol extracts were flavonoids, saponins and tannins. AGI activity in water extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 1.49%, 2.76% and 3.91%, respectively. AGI activity in ethanol extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 92.10%, 98.10% and 118.30%, respectively. While the AGI activity from glucobay were 99.50%. The optimum of AGI activity was in 1.5% ethanol extract. This AGI acivity which was not significantly different (α<0.05) from the 1% glucobay.

AKTIVITAS ANTIHIPERGLIKEMIA EKSTRAK AIR DAN HEKSANA DAUN PANDAN WANGI (Pandanus amaryllifolius) TERHADAP TIKUS PUTIH (Rattus novergicus) Sitaresmi Yuningtyas; Siti Mariam; Auliatun Nisa
Jurnal Farmamedika (Pharmamedika Journal) Vol 2 No 2 (2017): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Diabetes mellitus is a disorder of carbohydrate metabolism characterized by high blood glucose levels, or hyperglycemia. Hyperglycemia is a condition where the amount of glucose in the blood exceeds normal limits. Many plants that have the potential as the lowering of blood glucose levels, one of which pandan leaves (Pandanus amaryllifolius). The purpose this study were to identified class of chemicals compounds contained in extracts of water and hexane pandan leaves. Beside that, this study was conducted to determine the activity extracts of water and hexane pandan leaves to decrease blood glucose levels of white rats (Rattus novergicus) with hyperglycemia. Simplicia of pandan leaves extracted by maceration method. Condensed extract contains compounds defined and tested in vivo in rats induced by alloxan. Water extract of pandan leaves (EADP) contained alkaloids, flavonoids, saponins and tannins. Hexane extract of pandan leaves (EHDP) contained alkaloids and steroids. Measurement of blood glucose levels were measured by using a glucometer for 15 days with intervals in every 3 days. Negative control treatment with Na-CMC 1% was increased in blood glucose levels to 137.50%. Metfomin as positive control treatment with 9 mg could decrease the blood glucose levels to 66.41%. Treatment with EADP 300, EADP 600, EHDP 300 and EHDP 600 could decrease glucose levels 42.38, 60.25, 26.99 and 24.81% respectively. Therefore, water and hexane extracts of pandan leaves (Pandanus amaryllifolius) could decrease the blood glucose levels with in vivo.

POTENSI ENZIM TRANSGLUTAMINASE SEBAGAI GEL PENYEMBUH LUKA STADIUM II PADA AYAM RAS JANTAN Sitaresmi Yuningtyas; Winugroho; Abdul Ghoni
Jurnal Farmamedika (Pharmamedika Journal) Vol 1 No 1 (2016): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

The transglutaminase (EC 2.3.2.13) is an enzyme that catalyses an acyl transfer reaction of the γ-carboxiamide groups glutamine residues in proteins, peptides and various primary amines. Enzyme transglutaminase helps to stabilized the fibrin monomer during the process of blood clotting. This research was to determine the activities of the wound healing process stage II in male broilers given the transglutaminase enzyme sample gels. In this researchgel formulationmadeenzymetransglutaminase1%, 3%, 5% and7%. Transglutaminaseenzymegelpreparationorganoleptictestandhomogeneity test. Furthermore,thegel formulationapplied to themalebroilersownwoundsstage II. Transglutaminaseenzymegel formulationhad ahomogeneoustexture, white, odorlesstypicalenzymetransglutaminase, andhad apH rangefrom 6.2 to 6.7. The percentagereduction inwoundlength ofstage IIinmalebroilersbyenzymetransglutaminaseperfomedgel1%, 3%, 5% , 7% and Bioplacenton® gel (positive control) were 80.54%, 99.00%, 99.67%, 87.25%, and 99.33% respectively. Based on analysis statisticsofANOVA, percentage reduction inwoundlength ofstage IIby treatment withtransglutaminasepreparationgel5% higher and significantly differentcompared totreatmentwithBioplacenton®(positive control). Hence, transglutaminaseenzymepreparations5% gelcanact as awound healerstage IIinmalebroilers.

PENENTUAN KADAR KAFEIN KOPI ROBUSTA TERFERMENTASIOLEH Enterococcus durans, Enterococcus sulfureus, DAN Lactococcus garvieae Sitaresmi Yuningtyas; Syahid Pratama Al-Wali; Winugroho
Jurnal Farmamedika (Pharmamedika Journal) Vol 1 No 2 (2016): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Many people like to drink coffee because it has a unique flavor. Coffee also containscaffeine,which is not good for health. One of the most famous type of coffee is civet coffee (kopi luwak).This coffee is unique because lower caffeine and in the process of this coffee should be consumedfirst by civet. The issue is populations of civet who began to decrease and the process that makes itdifficult to be produced on a large scale in a short time. In this research, we tried to apply culture ofEnterococcus durans, Enterococcus sulfureus, and Lactococcusgarviea for processing robustacoffee that resembles the civet coffee. This study aims to determine the caffeine content offermented of robusta coffee and the results will be compared with the civet coffee. Bacteria foundin the digestive system of civet had isolated and added in fermentation process of robusta coffee.Caffeine levels measured by HPLC.From these results it can be concluded that the caffeine contentin fermented of robusta coffee whichfermented using bacterial suspension Enterococcus durans,Enterococcus sulfureus andLactococcusgarvieaehad not been able to equal the caffeine content incivet coffee.Amount of caffeine in fermented of robusta coffee had lower than amount of caffeinein robusta coffee. Percentage of caffeine in fermented of robusta coffee, robusta coffee, and civetcoffeewere 1,20%, 1,90%, and 0,59% respectively.

AKTIVITAS ANTIOKSIDAN, TOTAL FENOL, DAN KADAR VITAMIN C DARI KOMBUCHA DAUN SALAM (Syzygium polyanthum (Wight) Walp.) Sitaresmi Yuningtyas; Eem Masaenah; Murniwati Telaumbanua
Jurnal Farmamedika (Pharmamedika Journal) Vol 6 No 1 (2021): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v6i1.116

Kombucha adalah hasil fermentasi teh dan gula oleh SCOBY (symbiotic culture of bacteria and yeast). Kombucha dapat dibuat dari daun yang tinggi fenol salah satunya adalah daun salam. Penelitian ini bertujuan menentukan aktivitas antioksidan, total fenol, dan kadar vitamin C dari kombucha daun salam. Pada penelitian ini menggunakan kombucha daun salam dibuat dengan konsentrasi 12,5; 25; 37,5; dan 50 g/l. Kombucha daun salam yang diperoleh di uji karakteristik kombucha daun salam meliputi uji fitokimia, pH serta pengujian aktivitas antioksidan, total fenol dan kadar vitamin C secara in vitro. Aktivitas antioksidan kombucha daun salam pada penelitian ini diperoleh 38,58%-75,05% dengan nilai IC50 sebesar 27 g/l, total fenol kombucha daun salam berkisar 4,74-51,972 ppm, dan kadar vitamin C antara 16,426-30,506 mg/100g. Berdasarkan uji total fenol, kadar vitamin C dan uji antioksidan maka kombucha daun salam memiliki aktivitas antioksidan.

AKTIVITAS INHIBISI ENZIM ?-GLUKOSIDASE EKSTRAK AIR DAN ETANOL UMBI LAPIS BAWANG MERAH (Allium ascalonicum) Sitaresmi Yuningtyas; Dian Setiawati Artianti
FITOFARMAKA: Jurnal Ilmiah Farmasi Vol 5, No 1 (2015): FITOFARMAKA
Publisher : Universitas Pakuan

Umbi lapis bawang merah (Allium ascalonicum) mempunyai potensi sebagaianalgesik, antiinflamasi, antimikobakterial, antifungi, dan antikanker. Namun mekanismeantidiabetes pada tanaman ini belum ditentukan. Salah satu varietas bawang merah diIndonesia adalah varietas Bima Brebes. Penelitian ini dilakukan untuk menguji potensiekstrak air dan etanol umbi lapis A. ascalonicum pada konsentrasi 1% sebagai inhibitor enzim?-glukosidase dan dibandingkan aktivitasnya dengan akarbosa 1% sebagai kontrol positif.Umbi lapis A. ascalonicum diekstraksi dengan menggunakan metode maserasi. Ekstrak airdan etanol dianalisis kandungan fitokimia dan daya inhibisinya terhadap enzim ?-glukosidasesecara metode in vitro. Aktivitas ?-glukosidase ditentukan dengan mengukur produk pnitrofenolyangdihasilkandarireaksienzimdansubstratp-nitrofenil-?-D-glukopiranosida(pNPG) menggunakan microplate absorbance reader pada panjang gelombang 410 nm. Hasiluji fitokimia menunjukkan bahwa ekstrak air umbi lapis A. ascalonicum mengandung flavonoid dan tanin. Selain itu, ekstrak etanol 96% dan ekstrak etanol 70% umbi lapis A. ascalonicum mengandung flavonoid, tanin, dan saponin. Ekstrak air, etanol 70%, etanol 96%umbi lapis A. ascalonicum pada konsentrasi 1% (b/v) dan akarbosa 1% dapat menginhibisiaktivitas enzim ?-glukosidase berturut-turut sebesar 11,75%, 4,48%, 20,92%, dan 99,37%.Hasil aktivitas inhibisi ketiga ekstrak ini berbeda nyata (p 0,05) dengan daya inhibisiakarbosa 1%. Hal ini mengindikasikan bahwa ekstrak air dan etanol umbi lapis A.ascalonicum berperan sebagai inhibitor enzim ?-glukosidase.

Title

Found 13 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 13 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 13 Documents
Search