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Journal : Jurnal Farmamedika (Pharmamedica Journal)

PENGARUH KOMBINASI EKSTRAK ETANOL KULIT PUTIH BUAH SEMANGKA (CITRULLUS LANATUS (THUNB.)) DAN AIR BONGGOL PISANG KEPOK (MUSA ACUMINATA X MUSA BALBISIANA (ABB GROUP)) TERHADAP PERTUMBUHAN RAMBUT TIKUS PUTIH JANTAN M. Ikhwan Setiawan; Anna P. Roswiem; Ika Wahyu Pertiwi
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 2 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.278 KB) | DOI: 10.47219/ath.v3i2.12

Abstract

White skin of watermelon and the liquid of kepok banana tree trunk empirically widely used as hair growth, In addition ethanol extract white skin of watermelon and the liquid of kepok banana tree trunk has also been scientifically proven able to accelerate the growth hair of the rat. However the research activity of the combination of the two against the hair growth has never done. The purpose of this research is to know the combination of both these extracts which can give of the most activity is good for hair growth. Ethanol extract of white skin of watermelon extraction is done by of maceration using a solvent of ethanol 70 %, as for getting the test sample is liquid of kepok banana tree trunk done by cutting down banana tree trunk approximately 50 cm above the ground surface then the stem of banana leaf his satin-the core then covered with plastic and silenced for one night. The results showed that the combination of liquid of kepok banana tree trunk and Ethanol extract white skin of watermelon (2:1) have a long hair growth activity higher than the positive control (Minoxidil), While hair growth activity of weights lower than the positive control (Minoxidil)
AKTIVITAS INHIBISI α-GLUKOSIDASE DARI EKSTRAK AIR DAN ETANOL DAUN SIMPUR AIR (Dillenia suffruticosa (Griff.) Martelli) Sitaresmi Yuningtyas; Anna P. Roswiem; Erfina
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 1 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.013 KB) | DOI: 10.47219/ath.v3i1.23

Abstract

Diabetes mellitus is a disorder of carbohydrate metabolism which characterized by hyperglycemia conditions. One of the mechanism from oral hypoglycemic drug is inhibition of α-glucosidase activity. Dillenia suffruticosa (Griff.) Martelli, known as "simpur air" has been used to treat diabetes mellitus. This study aims to determine the inhibition activity of α-glucosidase enzyme from water and ethanol extract simpur air leaves. Simpur air leaves extracted with water and ethanol 70% using maceration method. Parameter evaluated in this research were phytocemical screening and alpha glucosidase inhibiting (AGI) activity. The results showed that the active compounds in water and ethanol extracts were flavonoids, saponins and tannins. AGI activity in water extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 1.49%, 2.76% and 3.91%, respectively. AGI activity in ethanol extract from simpur air leaves at concentrations of 1%, 1.5% and 2% were 92.10%, 98.10% and 118.30%, respectively. While the AGI activity from glucobay were 99.50%. The optimum of AGI activity was in 1.5% ethanol extract. This AGI acivity which was not significantly different (α<0.05) from the 1% glucobay.