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Rulina Suradi
Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Health Professions Medicine & Pharmacology

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Effects of massage on behavior of full-term newborns Tri Sunarti Wahyutami; Soedjatmiko Soedjatmiko; Agus Firmansyah; Rulina Suradi
Paediatrica Indonesiana Vol 50 No 4 (2010): July 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.4.2010.187-92

Abstract

Background Baby massage is one of the touch stimulation that could be applied as soon as possible after birth. Giving massage regularly will affect the behavior of newborn.Objectives To explore the effects of ten-day massage on infant's behavior.Methods A randomized control trial was done from December 200S to March 2009. Full-term newborm were randomly assigned into massage group or control group. Babies in massage group were given massage by their mothers and supervised by midwives. All babies were evaluated twice, i.e., on day 1 and day 11, using Brazelton Scale (Neonatal Behavior Assessment Scale). The behavior was compared between the two groups.Results A total of 72 full-term newborn infants appropriate for gestational age were included in this study. Infants in the massage group sbowed significant difference in adaptive behavior compared to control group. Those adaptive behavior consisted of habituation (WMD 1.08 CI 95% 0.67 to 1.49, P<0.0001), social interaction (WMD 1.54 Cl 95% 1.23 to 1.84, P<0.0001), motor system (WMD 1.35 CI 95% 1.14 to 1.55, P<0.0001), organization state (P<0.0001), range of state (WMD 1.35 CI 95% 0.95 to 1.55, P< 0.0001), autonomic system (WMD 0.53 CI 95% 0.23 to 0.84, P<0.0001), end reflexes (P<0.0001).Conclusions Massage gives better adaptive behavior and reflexes of full-term newborns compared to those without massage.
Clinical features and survival pattern of central nervous system leukemia in children with acute lymphoblastic leukemia Hardiono D. Pusponegoro; Moeslichan M. Z.; Risma K. Kaban; Rulina Suradi; Endang Windiastuti
Paediatrica Indonesiana Vol 41 No 9-10 (2001): September 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (300.834 KB) | DOI: 10.14238/pi41.5.2001.247-52

Abstract

Infiltration of leukemic cells into the central nervous system (CNS) is one of the causes of neurological disorders in patients with acute lymphoblastic leukemia (ALL) that worsen the prognosis. This retrospective cohort study aimed to review the clinical manifestations of children with CNS leukemia, their survival pattern and the role of early CNS leukemial. The survival curve was developed by Kaplan-Meier method, while the comparison of survival curves was done with log-rank test. Among 128 new ALL patients, 23 (18.0%) patients suffered from CNS leukemia, while 13 (10.2%) suffered from early CNS leukemia and 10 (7.8%) suffered from relapsing CNS leukemia. CNS leukemia was more common in male, in those aged less than 2 years, in those with white blood cell (WBC) count above 50,000/ìl, and in patients type FAB-L2 ALL. The clinical manifestations most commonly found were decrease of consciousness (61%), vomiting (48%), cranial nerve palsy (44%), seizures (39%), and headache (26%). Relapsing CNS leukemia was more common in high risk (12.5%) compared with standard risk leukemia (5.7%). Patients with early CNS leukemia had a lower survival rate than those without early CNS leukemia (p = 0.0005). The percentage of patients with early CNS leukemia surviving up to 3 years was 26%. We conclude that early CNS leukemia could cause low survival ALL patients.
Clinical and laboratory features of childhood systemic lupus erythematosus and its course in Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta Zakiudin Munasir; Tuty Mariana; Rulina Suradi
Paediatrica Indonesiana Vol 41 No 7-8 (2001): July 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.202 KB) | DOI: 10.14238/pi41.4.2001.214-24

Abstract

A descriptive, retrospective study has been performed among 33 children with SLE during the period of January 1986 to December 1999 in Department of Child Health, Cipto Mangunkusumo Hospital. The results of the present study show that SLE in childhood was more commonly found in girls than in boys, with a ratio of 4.5: 1. The mean age of onset was 10.5 years and the mean age of diagnosis was 10.9 years, most frequently observed in the age of > 10 years and rarely found in the age of < 5 years. The time interval between the time of onset and time of diagnosis ranged from 1 to 24 months and the most frequent interval was 1-3 months. The most common initial symptoms were prolonged fever, rash on the skin and face, and athralgia. In its natural history of the disease, kidneys, skin/mucous membrane and joints are the most frequent organs involved. Most of the SLE patients develop anemia. Positive anti ds-DNA, ANA and decreased levels of C3 and C4 respectively in 28 (28/31), in 29 (29/30), in 25 (25/33), and in 19 (19/27) cases. LE cells were encountered only in four (4/17) cases.  Out of 11 cases upon which renal biopsies were done, the most common histological features were mesangeal glomerulonephritis (class II) and diffuse proliferative glomerulonephritis (class IV). The mean time interval between the onset and renal complication manifestations was 6.96 months, cardiac complication was 16.77 months, central nerve system was 22.71 months and lungs were 25.0 months. Duration of illness of patients with SLE ranged from 2 to 175 with the mean of 31.3 months. The causes of death were mostly due to gastrointestinal bleeding and renal failure.
Efficacy of oral erythromycin to enhance feeding tolerance in preterm infants Made Sukmawati; Rinawati Rohsiswatmo; Rulina Suradi; Pramita Gayatri
Paediatrica Indonesiana Vol 57 No 3 (2017): May 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (117.76 KB) | DOI: 10.14238/pi57.3.2017.154-9

Abstract

Background Feeding intolerance is a common condition that affects preterm infants. Erythromycin is a prokinetic agent used to treat feeding intolerance, but its efficacy remains inconclusive.Objective To evaluate the effectiveness of oral erythromycin to enhance feeding tolerance in preterm infants.Methods This prospective, randomized controlled trial in preterm infants was conducted at Sanglah Hospital, Denpasar, Bali, from June 2015 to January 2016. Eligible infants were randomized to receive either 12.5 mg/kg/dose oral erythromycin or a placebo, every 8 hours. The primary outcome was the time to establish full enteral feeding. The secondary outcomes were body weight at full enteral feeding and length of hospital stay.Results Of 62 initial subjects, 3 infants dropped out of the study. Thirty infants were given erythromycin and 29 infants were given placebo. The baseline characteristics of the two groups were similar, with mean of gestational ages of 31.4 (SD 1.7) weeks in the erythromycin group and 32.4 (SD 2.2) weeks in the placebo group. The median times to reach full enteral feeding did not significantly differ between the two groups, with 10 (SD 5.3) days in the erythromycin group vs. 8 (SD 6.5) days in the placebo group (P=0.345). Also, median body weights at full enteral feeding and lengths of hospital stay were not significantly different between the two groups.Conclusion Erythromycin of 12.5 mg/kg/dose every 8 hours as prophylactic treatment does not significantly enhance feeding tolerance in preterm infants. Median body weights at full enteral feeding and length of hospital stay are not significantly different between the erythromycin and placebo groups.
Co-Authors Agus Firmansyah Endang Windiastuti Hardiono D. Pusponegoro Made Sukmawati Moeslichan M. Z. Pramita Gayatri Rinawati Rohsiswatmo Risma K. Kaban Soedjatmiko Tri Sunarti Wahyutami Tuty Mariana Zakiudin Munasir