Garuda - Garba Rujukan Digital

Zakiudin Munasir

Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta

Author-ID : 3468742

Health Professions Medicine & Pharmacology

Published : 2 Documents Claim Missing Document

Claim Missing Document

Articles

Clinical and laboratory features of childhood systemic lupus erythematosus and its course in Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta Zakiudin Munasir; Tuty Mariana; Rulina Suradi
Paediatrica Indonesiana Vol 41 No 7-8 (2001): July 2001
Publisher : Indonesian Pediatric Society

A descriptive, retrospective study has been performed among 33 children with SLE during the period of January 1986 to December 1999 in Department of Child Health, Cipto Mangunkusumo Hospital. The results of the present study show that SLE in childhood was more commonly found in girls than in boys, with a ratio of 4.5: 1. The mean age of onset was 10.5 years and the mean age of diagnosis was 10.9 years, most frequently observed in the age of > 10 years and rarely found in the age of < 5 years. The time interval between the time of onset and time of diagnosis ranged from 1 to 24 months and the most frequent interval was 1-3 months. The most common initial symptoms were prolonged fever, rash on the skin and face, and athralgia. In its natural history of the disease, kidneys, skin/mucous membrane and joints are the most frequent organs involved. Most of the SLE patients develop anemia. Positive anti ds-DNA, ANA and decreased levels of C3 and C4 respectively in 28 (28/31), in 29 (29/30), in 25 (25/33), and in 19 (19/27) cases. LE cells were encountered only in four (4/17) cases. Â Out of 11 cases upon which renal biopsies were done, the most common histological features were mesangeal glomerulonephritis (class II) and diffuse proliferative glomerulonephritis (class IV). The mean time interval between the onset and renal complication manifestations was 6.96 months, cardiac complication was 16.77 months, central nerve system was 22.71 months and lungs were 25.0 months. Duration of illness of patients with SLE ranged from 2 to 175 with the mean of 31.3 months. The causes of death were mostly due to gastrointestinal bleeding and renal failure.

Exposure pattern of house dust mites in childhood asthma along the year: A series of 10 cases Zakiudin Munasir; Lenny S. Budi; Titi Sularyo; Sri Rezeki Hadinegoro
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

House dust mite (HDM) is one of the inhalant allergens causinginflammation of respiratory tract. More than 100 dust mites/ gram house dust may cause sensitization in childhood asthma, while more than >500 house dust mite/gram house dust may cause asthma attack. This report aimed to determine the exposure pattern of house dust mites on 10 asthmatic children during one year. Homevisit to all patients was done every month to obtain house dust sample, measurement of relative humidity, bed room temperature, and to evaluate the clinical scores and peak expiratory flow rate (PEFR). The range value of house dust mite/gram house dust was 0-340. This study shows that house dust mite may cause of acute asthma attack when accompanied by nonspesific stimuli. In September the relative humidity is high, the temperature is low, and the amount of house dust mite/gram of house dust is highest, in contrast to in August and December. This study shows no seasonalvariation. The amount of house dust mite/ gram of house dust was found higher at the mattress than in the floor of bed room. The species of house dust mite that predominantly found is Dermato- phagoides pteronyssinus. We conclude that house dust mite may cause acute asthma attack whenever accompanied by nonspesific stimulus.

Title

Found 2 Documents
Search

Abstract

Abstract

Title Search

Found 2 Documents Search

Abstract

Abstract

Title

Found 2 Documents
Search