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All Journal Acta Interna : The Journal of Internal Medicine Biomedika Jurnal Ilmiah Ekonomi Islam
Doni Priambodo
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Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Health Professions Medicine & Pharmacology Social Sciences

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PROGNOSTIC FACTORS OF LEPTOSPIROSIS PATIENTS IN DR. SARDJITO GENERAL HOSPITAL, YOGYAKARTA, INDONESIA Kurniaatmaja, E.R, Kurniaatmaja, E.R; Priambodo, Doni; Humardewayanti, Rizka; Loeheri, Soebagjo
Acta Interna The Journal of Internal Medicine Vol 1, No 2 (2011): Acta Interna The Journal of Internal Medicine
Publisher : Acta Interna The Journal of Internal Medicine

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Abstract

Background: Leptospirosis, an infectious disease that affects humans and animals, is a common zoonosis with a variety of clinical manifestations. Yogyakarta is one of the cities with a high incidence of leptospirosis. It is important to recognize the clinical features and prognostic factors of this disease. Severe disease can be fatal, although majority of cases are mild and self-limited. Objective: To determine the prognostic factors for leptospirosis that associated with mortality in patients with leptospirosis in Dr. Sardjito General Hospital, Yogyakarta. Methods: We conducted a retrospective study of data collected in our hospital between Jan 2010 until May 2011, from whom the diagnosis of leptospirosis was confirmed based on pertinent clinical and epidemiological data and positive serology. Result: Thirty two patients were included in this study, including 29 survivors (90.62%) and 3 non-survivors (9.38%). Of these 32 patients, 26 patients (81.25%) were admitted to the medical ward and 6 patients (18.75 %) were admitted to the ICU.  Multivariate logistic regression demonstrated that three factors were independently associated with mortality: oliguria (OR 0.75; CI 0.541–1.04; p<0.05); urea nitrogen > 74.7 mmol/L (OR 0.813; CI 0.642-1.028; p<0.05), and neurological symptoms (altered mentation or seizure) (OR 30; CI 4.367–206.07; p<0.05) Conclusion: The mortality of leptospirosis remains high despite improvements in patients care. In order to improve the early treatment of high-risk patients, these 2 clinical and 1 laboratory criteria which are associated with mortality, can be used at the time of admission as prognostic factors.  Keywords : Leptospirosis, prognostic factors, mortality
CEPHALIC TETANUS A RARE LOCAL TETANUS Nur Mahmudah, Iin Novita; Priambodo, Doni
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Woman, 68 years old came to hospital with chief complain trismus and dysphagia. She was in a good condition with physical examination and standard laboratory test reveal normal value. The neurologist found multiple parese of cranial nerve (V, VII, IX, X, XI). After further examination include electromedic test and head ct scan with contrast the neurologist did not find any abnormality that may explain her symptoms. The patient then consulted to the internist with suspect of local tetanus infection because of focal infection in her dental caries. The patient is then treated with antibiotics, convultion inhibitor agent, also given tetanus immunoglobulin. During the treatment, her symptoms improved. There were no other severe complication. Patient was returning home on the ninth day of hospitalisation and ready for her dentist appointment.Keywords : Trismus, dysphagia, parese, tetanus, tetanus imunoglobulin
CEPHALIC TETANUS A RARE LOCAL TETANUS Nurhidayati Mahmuda, Iin Novita; Priambodo, Doni
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v7i2.1872

Abstract

Woman, 68 years old came to hospital with chief complain trismus and dysphagia. She was in a good condition with physical examination and standard laboratory test reveal normal value. The neurologist found multiple parese of cranial nerve (V, VII, IX, X, XI). After further examination include electromedic test and head ct scan with contrast the neurologist did not find any abnormality that may explain her symptoms. The patient then consulted to the internist with suspect of local tetanus infection because of focal infection in her dental caries. The patient is then treated with antibiotics, convultion inhibitor agent, also given tetanus immunoglobulin. During the treatment, her symptoms improved. There were no other severe complication. Patient was returning home on the ninth day of hospitalisation and ready for her dentist appointment.Keywords : Trismus, dysphagia, parese, tetanus, tetanus imunoglobulin
Analysis of the Influence Theory off Planned Behavior on Interest in Money Waqf (Case Study in Dompet Dhuafa Republika) Doni Priambodo
Jurnal Ilmiah Ekonomi Islam Vol 8, No 1 (2022): JIEI : Vol. 8, No. 1, 2022
Publisher : ITB AAS INDONESIA Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29040/jiei.v8i1.3785

Abstract

Abstract Cash waqf can be in the form of cash waqf given from the wakif to the institution receiving the cash waqf. This research aims to analyze the effect of Theory of Planned Behavior (Attitudes, Norms and Behavioral Control) on the interest of waqif in waqf money with a case study at the Dompet Dhuafa Republika Waqf Institute. The strategy of gathering information in this investigation was through the delivery of questionnaires to the wakif as many as 105 respondents. The information collected was analyzed using the Structural Equation Modeling approach with the AMOS program. The results obtained are that there is a positive and significant influence between behavioral and normative factors on interest in waqf for cash waqf, while the behavioral control variable has no positive and fundamental effect on interest in cash waqf. This paper is expected to provide benefits for cash waqf management institutions in understanding the behavior of waqf in cash waqf so that it can be used as a guide in advancing procedures for collecting cash waqf funds. Keywords: Cash Waqf, Theory Plannned of Behavior JEL Classification: Management and Cash Waqf
PROGNOSTIC FACTORS OF LEPTOSPIROSIS PATIENTS IN DR. SARDJITO GENERAL HOSPITAL, YOGYAKARTA, INDONESIA Kurniaatmaja, E.R Kurniaatmaja, E.R; Doni Priambodo; Rizka Humardewayanti; Soebagjo Loeheri
Acta Interna The Journal of Internal Medicine Vol 1, No 2 (2011): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.759 KB) | DOI: 10.22146/acta interna.3867

Abstract

Background: Leptospirosis, an infectious disease that affects humans and animals, is a common zoonosis with a variety of clinical manifestations. Yogyakarta is one of the cities with a high incidence of leptospirosis. It is important to recognize the clinical features and prognostic factors of this disease. Severe disease can be fatal, although majority of cases are mild and self-limited. Objective: To determine the prognostic factors for leptospirosis that associated with mortality in patients with leptospirosis in Dr. Sardjito General Hospital, Yogyakarta. Methods: We conducted a retrospective study of data collected in our hospital between Jan 2010 until May 2011, from whom the diagnosis of leptospirosis was confirmed based on pertinent clinical and epidemiological data and positive serology. Result: Thirty two patients were included in this study, including 29 survivors (90.62%) and 3 non-survivors (9.38%). Of these 32 patients, 26 patients (81.25%) were admitted to the medical ward and 6 patients (18.75 %) were admitted to the ICU.  Multivariate logistic regression demonstrated that three factors were independently associated with mortality: oliguria (OR 0.75; CI 0.541–1.04; p<0.05); urea nitrogen > 74.7 mmol/L (OR 0.813; CI 0.642-1.028; p<0.05), and neurological symptoms (altered mentation or seizure) (OR 30; CI 4.367–206.07; p<0.05) Conclusion: The mortality of leptospirosis remains high despite improvements in patients care. In order to improve the early treatment of high-risk patients, these 2 clinical and 1 laboratory criteria which are associated with mortality, can be used at the time of admission as prognostic factors.  Keywords : Leptospirosis, prognostic factors, mortality
Th e Accuracy of Delta Neutrophil Index as a Marker of Sepsis Severity Level Compare to Serum Amyloid A Silvikarina Erfanti Dewi Halim; Rizka Humardewayanti Asdie; Doni Priambodo
Acta Interna The Journal of Internal Medicine Vol 9, No 1 (2019): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.961 KB) | DOI: 10.22146/actainterna.50906

Abstract

Background. Early diagnosis of infection before its progression to become organ dysfunction or circulation failure has an important clinical effect and critical patient outcome. Diagnostic modality used as a gold standard on diagnosing sepsis condition still relies on microbe culture. Microbial culture needed a long duration to grow bacteria in high numbers be identified. The upcoming alternative diagnostic modality used as a marker of sepsis severity level was Delta Neutrophil Index (DNI) and Serum Amyloid A (SAA). There were no references to compare the accuracy of DNI and SAA as a marker of sepsis severity level.Methods. 45 study subjects were patients with sepsis and severe sepsis or septic shock first known when first come to the ER or underwent treatment in the inpatient unit, ICU (Intensive Care Unit) or IMC (Intermediate Care) Sardjito’s Hospital that fulfilled the inclusion and exclusion criteria. The independent variable was DNI and the dependent variable was sepsis severity level. All of blood samples from septic patient undergo DNI and SAA test. Distributed data used the Kolmogorov-Smirnov test. DNI and SAA accuracy used sensitivity, specificity, positive predictive value, negative predictive value, like hood ratio and receiver-operating characteristics (ROC) curve.Results. The study consisted of 45 study subjects. The mean age was 52.98 years. The mean of SAA in this study was 54.39 ± 45.53 mg/L, while the mean of DNI in this study was 12.47 ± 8.79 %. Cut off point DNI 6.85% with value of sensitivity 93%, specificity 70%, positive predictive value (PPV) 79.31%, and negative predictive value (NPV) 87.5%, like hood ratio for a positive test result (LR+) (PLR) 14.28 and like hood ratio for a negative test result (LR-) (NLR) 3.3. Cut off for SAA 54.93 mg/L with value of sensitivity 60%, specificity 56%, positive predictive value (PPV) 52%, negative predictive value (NPV) 64%, like hood ratio for a positive test result (LR+) (PLR) 1.36 and likelihood ratio for a negative test result (LR-) (NLR) 0.71.Conclusions. DNI has better diagnostic accuracy value as a marker of sepsis severity level than SAA.Keywords. Sepsis, sepsis severity level, Delta Neutrophil Index (DNI), Serum Amyloid A (SAA)
CEPHALIC TETANUS A RARE LOCAL TETANUS Iin Novita Nurhidayati Mahmuda; Doni Priambodo
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v7i2.1872

Abstract

Woman, 68 years old came to hospital with chief complain trismus and dysphagia. She was in a good condition with physical examination and standard laboratory test reveal normal value. The neurologist found multiple parese of cranial nerve (V, VII, IX, X, XI). After further examination include electromedic test and head ct scan with contrast the neurologist did not find any abnormality that may explain her symptoms. The patient then consulted to the internist with suspect of local tetanus infection because of focal infection in her dental caries. The patient is then treated with antibiotics, convultion inhibitor agent, also given tetanus immunoglobulin. During the treatment, her symptoms improved. There were no other severe complication. Patient was returning home on the ninth day of hospitalisation and ready for her dentist appointment.Keywords : Trismus, dysphagia, parese, tetanus, tetanus imunoglobulin
Co-Authors E.R Kurniaatmaja E.R Kurniaatmaja Iin Novita Nurmahmudah, Iin Novita Rizka Humardewayanti Asdie Silvikarina Erfanti Dewi Halim Soebagjo Loeheri