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All Journal Biomedika JURNAL PENDIDIKAN TAMBUSAI Solo Journal of Anesthesi, Pain and Critical Care KESANS : International Journal of Health and Science Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika International Journal of Health Science and Technology
Iin Novita Nurmahmudah, Iin Novita
Universitas Muhammadiyah Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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EFEK INFUSA AKAR TEMPUYUNG (SONCHUS ARVENSIS) TERHADAP PENURUNAN KADAR ASAM URAT PADA TIKUS PUTIH (RATTUS NORVEGICUS) Retnowati, Kurnia; Sutrisna, EM; Nurmahmudah, Iin Novita
Biomedika Vol 6, No 2 (2014): Biomedika Agustus 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tempuyung (Sonchus arvensis) consisted of fiavonoid were effect as obstruct xantine oksidase enzyme, antioxidant captur superoxsidase radical. The fiavonoid total in leave of tempuyung is 0,1044%, in its root have 0,5% fiavonoid and the more is apigenin-7-O-glikosida (3,4,5). This research aim to know effect of infusa root of tempuyung (Sonchus arvensis) to lower the uric acid level at blood serum and infusa root of Tempuyung (Sonchus arvensis) to lower the uric acid level at mouse blood serum compared to allopurinol.This research is laboratory experimental method. The object were 25 Wistar male mice 2-3 months old, 150-200 gr divided into 5 groups. Negative Control group given potassium oxonate by intraperitoneal, Positive Control group given potassium oxonate by intraperitoneal, added by allopurinol 18mg/kgBB, Infusa Concentrated Group 1 given potassium oxonate by intraperitoneal added by infusa root of tempuyung 1,25g/kgBB, Infusa Concentrated Group 2 given potassium oxonate by intraperitoneal added by infusa root of tempuyung 2,5g/kgBB, Infusa Concentrated Group 3 given potassium oxonate by intraperitoneal added by infuse root of tempuyung 5g/kgBB. Executed until one day, where measurement of uric acid of mouse blood serum done before and after treatment. Measurement of uric acid level is done by using spectrophotometer. Obtained to be data to be analysed with Kolgomorov-Smirnov test, One-Way ANOVA and continued with LSD (Least Significant Difference) test with 95% confidence interval (CI). Result of statistical test of research shoe that infusa root of Tempuyung (Sonchus arvensis) dose 1,25g/kgBB, 2,5g/ kgBB, 5g/kgBB have effect to lower the uric acid level at mouse blood serum. Infusa root of Tempuyung (Sonchus arvensis) concentrated 5g/kgBB proportional wih dose allopurinol 18mg/kgBB to lower the uric acid level at mouse blood serum.Keyword: Infusa, root of Tempuyung (Sonchus arvensis), uric acid
CEPHALIC TETANUS A RARE LOCAL TETANUS Nur Mahmudah, Iin Novita; Priambodo, Doni
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

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Abstract

Woman, 68 years old came to hospital with chief complain trismus and dysphagia. She was in a good condition with physical examination and standard laboratory test reveal normal value. The neurologist found multiple parese of cranial nerve (V, VII, IX, X, XI). After further examination include electromedic test and head ct scan with contrast the neurologist did not find any abnormality that may explain her symptoms. The patient then consulted to the internist with suspect of local tetanus infection because of focal infection in her dental caries. The patient is then treated with antibiotics, convultion inhibitor agent, also given tetanus immunoglobulin. During the treatment, her symptoms improved. There were no other severe complication. Patient was returning home on the ninth day of hospitalisation and ready for her dentist appointment.Keywords : Trismus, dysphagia, parese, tetanus, tetanus imunoglobulin
CEPHALIC TETANUS A RARE LOCAL TETANUS Nurhidayati Mahmuda, Iin Novita; Priambodo, Doni
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v7i2.1872

Abstract

Woman, 68 years old came to hospital with chief complain trismus and dysphagia. She was in a good condition with physical examination and standard laboratory test reveal normal value. The neurologist found multiple parese of cranial nerve (V, VII, IX, X, XI). After further examination include electromedic test and head ct scan with contrast the neurologist did not find any abnormality that may explain her symptoms. The patient then consulted to the internist with suspect of local tetanus infection because of focal infection in her dental caries. The patient is then treated with antibiotics, convultion inhibitor agent, also given tetanus immunoglobulin. During the treatment, her symptoms improved. There were no other severe complication. Patient was returning home on the ninth day of hospitalisation and ready for her dentist appointment.Keywords : Trismus, dysphagia, parese, tetanus, tetanus imunoglobulin
EFEK INFUSA AKAR TEMPUYUNG (SONCHUS ARVENSIS) TERHADAP PENURUNAN KADAR ASAM URAT PADA TIKUS PUTIH (RATTUS NORVEGICUS) Retnowati, Kurnia; Sutrisna, EM; Nurhidayati Mahmuda, Iin Novita
Biomedika Vol 6, No 2 (2014): Biomedika Agustus 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v6i2.274

Abstract

Tempuyung (Sonchus arvensis) consisted of fiavonoid were effect as obstruct xantine oksidase enzyme, antioxidant captur superoxsidase radical. The fiavonoid total in leave of tempuyung is 0,1044%, in its root have 0,5% fiavonoid and the more is apigenin-7-O-glikosida (3,4,5). This research aim to know effect of infusa root of tempuyung (Sonchus arvensis) to lower the uric acid level at blood serum and infusa root of Tempuyung (Sonchus arvensis) to lower the uric acid level at mouse blood serum compared to allopurinol.This research is laboratory experimental method. The object were 25 Wistar male mice 2-3 months old, 150-200 gr divided into 5 groups. Negative Control group given potassium oxonate by intraperitoneal, Positive Control group given potassium oxonate by intraperitoneal, added by allopurinol 18mg/kgBB, Infusa Concentrated Group 1 given potassium oxonate by intraperitoneal added by infusa root of tempuyung 1,25g/kgBB, Infusa Concentrated Group 2 given potassium oxonate by intraperitoneal added by infusa root of tempuyung 2,5g/kgBB, Infusa Concentrated Group 3 given potassium oxonate by intraperitoneal added by infuse root of tempuyung 5g/kgBB. Executed until one day, where measurement of uric acid of mouse blood serum done before and after treatment. Measurement of uric acid level is done by using spectrophotometer. Obtained to be data to be analysed with Kolgomorov-Smirnov test, One-Way ANOVA and continued with LSD (Least Significant Difference) test with 95% confidence interval (CI). Result of statistical test of research shoe that infusa root of Tempuyung (Sonchus arvensis) dose 1,25g/kgBB, 2,5g/ kgBB, 5g/kgBB have effect to lower the uric acid level at mouse blood serum. Infusa root of Tempuyung (Sonchus arvensis) concentrated 5g/kgBB proportional wih dose allopurinol 18mg/kgBB to lower the uric acid level at mouse blood serum.Keyword: Infusa, root of Tempuyung (Sonchus arvensis), uric acid
PERBEDAAN KADAR ASAM URAT PADA PENDERITA HIPERTENSI DENGAN DIABETES MELITUS TIPE 2 DAN TANPA DIABETES MELITUS TIPE 2 Nurhidayati Mahmuda, Iin Novita; Maulana, Yudrik; Oktoviano R, Indriyati
Biomedika Vol 8, No 1 (2016): Biomedika Februari 2016
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v8i1.3021

Abstract

Peningkatan kadar asam urat memegang peranan penting pada terjadinya morbiditas pasien hipertensi. Diabetes mellitus (DM) merupakan komorbid yang sering ditemukan pasien hipertensi. Tujuan penelitian ini adalah untuk mengetahui perbedaan kadar asam urat pada penderita hipertensi dengan DM tipe 2 dan tanpa DM tipe 2 di Rumah Sakit Umum Daerah Dr. Sayidiman Magetan. Penelitiian ini merupakan melakukan penelitian analitik observasional dengan rancangan penelitian cross sectional. Subjek penelitian adalah penderita hipertensi dengan DM tipe 2 dan tanpa DM tipe 2 di RSUD Dr. Sayidiman. Teknik pengambilan sampel dilakukan secara consecutive sampling. Data diperoleh dari data rekam medik pasien periode Januari 2012 hingga Juni 2015. Penelitian ini menggunakan 54 sampel, terdiri dari 27 pasien pada kelompok hipertensi dengan DM tipe 2 dan 27 pasien pada kelompok hipertensi tanpa DM tipe 2. Pada uji t, didapatkan bahwa rerata kadar asam urat pada kelompok hipertensi dengan DM (6,559±2,2560 mg/dl) lebih besar dibandingkan dengan kelompok hipertensi tanpa DM tipe 2 (4,922±1.3051 mg/dl) secara signifikan (p=0,002). Kesimpulan: Rerata kadar asam urat pada kelompok hipertensi dengan DM tipe 2 lebih besar dibandingkan dengan kelompok hipertensi tanpa DM tipe 2.Kata kunci: Kadar asam urat, Hipertensi, DM tipe 2
PENCEGAHAN DAN TATALAKSANA DEKUBITUS PADA GERIATRI Mahmuda, Iin Novita Nurhidayati
Biomedika Vol 11, No 1 (2019): Biomedika Februari 2019
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v11i1.5966

Abstract

Decubitus ulcer or pressure sore is a serious morbidity in elderly patients. The incidence of pressure sores in geriatric patients is 11%. Population at 70-75 of their aged had a two-fold risk higher for suffering decubitus ulcers compared with 55-69 years of aged people. The highest incidence is in group of 80-84 years old peole. Studies has found 95% of cases are preventable. Prevention efforts have already proven to be more effective and cost effective than treatment. Prevention efforts include mobilization, skin care, fulfillment of fluids and adequate nutrition, the use of tools / aids for body movement, environmental regulation of health care and education. Treatment of decubitus ulcers by administering topical material, systemic drugs or surgery should be done as early as possible. Keyword: decubitus ulcer, geriatric patients, prevention, treatment 
HIPERGLIKEMIA SEBAGAI PREDIKTOR KEBERHASILAN PENGOBATAN PASIEN DENGAN SINDROM KORONER AKUT DI RSUD X SURAKARTA Mahmuda, Iin Novita Nurhidayati; Rezki, Yuniana Nur; Priscillah, Wildan
Biomedika Vol 10, No 2 (2018): Biomedika Agustus 2018
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v10i2.7023

Abstract

ABSTRAK Sindrom Koroner Akut atau acute coronary syndrome (ACS) dengan hiperglikemia pada saat masuk memiliki rerata mortalitas yang lebih tinggi, pada penelitian terbaru. Hiperglikemia pada pasien dengan ACS digambarkan sebagai respon akut dari keadaan hiperadrenergik dengan peningkatan risiko trombosis, sehingga bisa memperburuk kondisi pasien ACS selama dirawat di rumah sakit. Tujuan penelitian ini untuk mengetahui perbedaan lama tinggal dan mortalitas pada pasien ACS dengan stres hiperglikemia dan tanpa hiperglikemia stres. Jenis penelitian ini adalah penelitian observasional  analitik dengan pendekatan cross sectional. Subjek penelitian adalah pasien ACS non-diabetes di RSUD X Surakarta. Data diperoleh dari rekam medis dengan teknik purposive sampling, dianalisis dengan uji Mann-Whitney. Subjek penelitian sebanyak 68 pasien, 34 pasien ACS dengan hiperglikemia dan 34 pasien ACS tanpa hiperglikemia. Hasil penelitian ini menyatakan ada perbedaan durasi lama tinggal pasien ACS dengan dan tanpa hiperglikemia(p = 0,002) dan tidak ada perbedaan rerata mortalitas diantara keduanya.Kata kunci: Sindrom Koroner Akut, Hiperglikemia, Lama Rawat Inap, Mortalitas ABSTRACT Acute Coronary Syndrome (ACS) in recent studies has been associated with hyperglycemia at the time of admission with higher mortality rates. Hyperglycemia in patients with ACS described as an acute response from a hyperadrenergic state with an increased risk of thrombosis, so it could worsen the condition of the patient ACS during the hospital stay. Aims of this study are to know differences in length of stay and mortality in ACS patients with hyperglycemia stress and without hyperglycaemia stress. This was an analytical observational research design with  cross sectional approach. The subjects were non diabetic ACS patient in RSUD X Surakarta. Data were obtained from medical record with purposive sampling technique, analyzed by Mann-Whitney test. Subjects were 68 patients, 34 patients ACS with hyperglycemia and 34 patients ACS without hyperglycemia. There is a difference in duration long of stay ACS patients with and without hyperglycemia (p = 0.002) and there is no difference in mortality.Keywords: Acute Coronary Syndrome, Hyperglycemia, Length Of Hospitalization, Mortality
Tingkat Kepatuhan Protokol Kesehatan dan Cakupan Vaksinasi pada Mahasiswa UMS yang Terpapar Covid-19 Jati, Izzah Tsaqoofah; Nurhidayati Mahmuda, Iin Novita
Jurnal Pendidikan Tambusai Vol. 6 No. 1 (2022): April 2022
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (200.562 KB)

Abstract

COVID-19 merupakan pandemi yang saat ini sedang terjadi di dunia yang disebabkan oleh virus yang disebut dengan Severe-Acute-Respiratory-Syndrome Corona Virus 2 (SARS-CoV-2). Penyebaran penyakit ini melalui interaksi dengan jarak yang dekat dan disebarkan melalui media perantara droplet ketika terjadi batuk, bersin, atau berbicara. Salah satu upaya penanggulangan covid-19 yaitu menerapkan protokol kesehatan (prokes) dan melakukan vaksinasi covid-19. Tujuan: Untuk mengetahui tingkat kepatuhan protokol kesehatan dan cakupan vaksinasi pada mahasiswa UMS yang terpapar covid-19. Metode: Jenis penelitian adalah penelitian deskritif observasional dengan desain cross sectional. Teknik sampling menggunakan pengambilan sampel total. Metode pengumpulan data menggunakan kuesioner google from online. Hasil: Karakteristik responden, mayoritas berusia 20-21 tahun 35 (58,3%), jenis kelamin perempuan 46 (76,7%), tinggi badan rata-rata 161,1, berat badan rata-rata 59,15, responden yang rutin olah raga 30 (50%) dan tidak olah raga 30 (50%), mayoritas responden rutin mengkonsumsi vitamin 31 (51,7%) dan mahasiwa yang sudah pernah terkonfirmasi 60 (100%). Tingkatan kepatuhan mahasiswa terhadap protokol kesehatan kesehatan termasuk dalam kategoti disiplin 38 (63,3%). Mahasiswa yang belum vaksinasi sebanyak 40 (66,7%), dosis 1 sebanyak 13 (21,7%), dosis 2 sebanyak 7 (11,7%). Kesimpulan: Tingkat kepatuhan mahasiswa terhadap protokol kesehatan termasuk dalam kategori disiplin. Tingkat cakupan vaksinasi covid-19 dikalangan mahasiswa UMS masih tergolong rendah saat dilaksanakan penelitian ini.
PERBEDAAN KADAR ASAM URAT PADA PENDERITA HIPERTENSI DENGAN DIABETES MELITUS TIPE 2 DAN TANPA DIABETES MELITUS TIPE 2 Iin Novita Nurhidayati Mahmuda; Yudrik Maulana; Indriyati Oktoviano R
Biomedika Vol 8, No 1 (2016): Biomedika Februari 2016
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v8i1.3021

Abstract

Peningkatan kadar asam urat memegang peranan penting pada terjadinya morbiditas pasien hipertensi. Diabetes mellitus (DM) merupakan komorbid yang sering ditemukan pasien hipertensi. Tujuan penelitian ini adalah untuk mengetahui perbedaan kadar asam urat pada penderita hipertensi dengan DM tipe 2 dan tanpa DM tipe 2 di Rumah Sakit Umum Daerah Dr. Sayidiman Magetan. Penelitiian ini merupakan melakukan penelitian analitik observasional dengan rancangan penelitian cross sectional. Subjek penelitian adalah penderita hipertensi dengan DM tipe 2 dan tanpa DM tipe 2 di RSUD Dr. Sayidiman. Teknik pengambilan sampel dilakukan secara consecutive sampling. Data diperoleh dari data rekam medik pasien periode Januari 2012 hingga Juni 2015. Penelitian ini menggunakan 54 sampel, terdiri dari 27 pasien pada kelompok hipertensi dengan DM tipe 2 dan 27 pasien pada kelompok hipertensi tanpa DM tipe 2. Pada uji t, didapatkan bahwa rerata kadar asam urat pada kelompok hipertensi dengan DM (6,559±2,2560 mg/dl) lebih besar dibandingkan dengan kelompok hipertensi tanpa DM tipe 2 (4,922±1.3051 mg/dl) secara signifikan (p=0,002). Kesimpulan: Rerata kadar asam urat pada kelompok hipertensi dengan DM tipe 2 lebih besar dibandingkan dengan kelompok hipertensi tanpa DM tipe 2.Kata kunci: Kadar asam urat, Hipertensi, DM tipe 2
EFEK INFUSA AKAR TEMPUYUNG (SONCHUS ARVENSIS) TERHADAP PENURUNAN KADAR ASAM URAT PADA TIKUS PUTIH (RATTUS NORVEGICUS) Kurnia Retnowati; EM Sutrisna; Iin Novita Nurhidayati Mahmuda
Biomedika Vol 6, No 2 (2014): Biomedika Agustus 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v6i2.274

Abstract

Tempuyung (Sonchus arvensis) consisted of fiavonoid were effect as obstruct xantine oksidase enzyme, antioxidant captur superoxsidase radical. The fiavonoid total in leave of tempuyung is 0,1044%, in its root have 0,5% fiavonoid and the more is apigenin-7-O-glikosida (3,4,5). This research aim to know effect of infusa root of tempuyung (Sonchus arvensis) to lower the uric acid level at blood serum and infusa root of Tempuyung (Sonchus arvensis) to lower the uric acid level at mouse blood serum compared to allopurinol.This research is laboratory experimental method. The object were 25 Wistar male mice 2-3 months old, 150-200 gr divided into 5 groups. Negative Control group given potassium oxonate by intraperitoneal, Positive Control group given potassium oxonate by intraperitoneal, added by allopurinol 18mg/kgBB, Infusa Concentrated Group 1 given potassium oxonate by intraperitoneal added by infusa root of tempuyung 1,25g/kgBB, Infusa Concentrated Group 2 given potassium oxonate by intraperitoneal added by infusa root of tempuyung 2,5g/kgBB, Infusa Concentrated Group 3 given potassium oxonate by intraperitoneal added by infuse root of tempuyung 5g/kgBB. Executed until one day, where measurement of uric acid of mouse blood serum done before and after treatment. Measurement of uric acid level is done by using spectrophotometer. Obtained to be data to be analysed with Kolgomorov-Smirnov test, One-Way ANOVA and continued with LSD (Least Significant Difference) test with 95% confidence interval (CI). Result of statistical test of research shoe that infusa root of Tempuyung (Sonchus arvensis) dose 1,25g/kgBB, 2,5g/ kgBB, 5g/kgBB have effect to lower the uric acid level at mouse blood serum. Infusa root of Tempuyung (Sonchus arvensis) concentrated 5g/kgBB proportional wih dose allopurinol 18mg/kgBB to lower the uric acid level at mouse blood serum.Keyword: Infusa, root of Tempuyung (Sonchus arvensis), uric acid
Co-Authors Angiesta Pinakesty Anteng Naruma Bambang Sutanto Dessy Dessy Devan Adil Syah Doni Priambodo Em Sutrisna Erika Diana Risanti Fairuz Ulfah Fakhri Nofaldi Faridita Khoirun Nisa Febrian Dwi Cahyo Ferika Dian Syafitri Hafish Harfian Rajendra Idoviari Putriyantiwi Indriyati Oktoviano R Jati, Izzah Tsaqoofah Kurnia Retnowati Kurnia Retnowati, Kurnia Laisa Khotik Listiana Masyita Dewi Maulana, Yudrik Nadia Wdihi Aqmarina Nanda Dhea Ayu Sawitri Nanda Nurkusumasari Nandya Herdiana Nida Faradisa Fauziyah Niken Sari Oktafiani Oktoviano R, Indriyati Poetrie Wulandari Ruswandi Prihatin Puji Astuti Priscillah, Wildan Raafika Studiviani Dwi Binuko Rahmat Dani Yamsun Ratnasari Bondan Wijayanti Reza Khairunnisa Rezki, Yuniana Nur Riandini Aisyah Rizky Febrian Rochmadina Suci Bestari Safari Wahyu Jatmiko Sheila Faadhila Sifak Syah Fillia Nurul Maslahah Tri Agustina Triana Rahma Juwita Tyas Hanurita Subekti Ulfah, Fairuz Wildan Priscillah Yudrik Maulana Yuniana Nur Rezki