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Journal : JIMKI : Jurnal Ilmiah Mahasiswa Kedokteran Indonesia

KOMBUCHA: PENDAYAGUNAAN MEKANISME GUT-BRAIN AXIS DALAM PENCEGAHAN DEPRESI Putu Diah Ananda Putri Atmaja; Abiyyu Didar Haq; Visakha Vidyadevi Wiguna
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 9 No 3 (2022): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 9.3 Edisi Desember 202
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v9i3.333

Abstract

Background: COVID-9 pandemic brings a devastating change on every aspect of everyday life around the world. The change that is happening has been proven to act as a risk factor for many mental illnesses, including depression. Many efforts that has been done mainly focuses on curative aspect of depression and only a small portion of it focuses on the preventive aspect. Methods: This literature review uses a variety of articles sourced from several online publication databases such as National Center for Biotechnology Information (NCBI), Garba Rujukan Digital (GARUDA), and Google Scholar. Discussion: Many clinical studies has proved that there are indeed a connection between gut microbiote witf the nervous system which researchers called Gut-Brain Axis (GBA). Gut microbiote plays a key role in maintaining GBA homeostasis and its relation with one’s mental health. Probiotic consumption is one of many efforts that people do to maintain that homeostasis in order to maintain their mental health. Made of tea, sugar, and Symbitoic Culture of Bacteria and Yeasts (SCOBY) , kombucha is a fermented beverage that has been proven to bring positve impacts on gut microbiote with more than 50 probiotics and beneficial molecules. Conclusion: Utilization of kombucha to maintain GBA has the potential to completes the fight against depression especially in the aspect of prevention
POTENSI EKSTRAK BUNGA KAMBOJA (PLUMERIA SP.) DAN BUNGA KLUWIH (ARTOCARPUS CAMANSI) SEBAGAI BIOLARVASIDA NYAMUK ANOPHELES SP. DALAM UPAYA PENCEGAHAN PENYAKIT MALARIA Luh Gde Sri Adnyani Suari; Abiyyu Didar Haq; Luh Ade Dita Rahayu
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 8 No 3 (2021): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 8.3 Edisi September 20
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v8i3.267

Abstract

ABSTRACT Background: Malaria is one of many health problem that attracts attention in a lot of countries, especially Indonesia as a tropical country. To minimalize the spread of malaria, many efforts is done to control Anopheles sp as the vector of malaria. Some of many effort that has been done to control malaria is larvaciding. Conventional insecticide such as malathion, DDT, and pyrethroid that is widely used for vector control is known to cause problem such as pollution, residual effect, and resistance of the mosquitoes. Therefore, it is very much needed to find an alternative of the overuse of insecticide and find a better and safer solution both for us and for the environment . Methods: This literature review used a variety of sources that are being retrieved from online publication portal. Discussion: Extract of Plumeria sp. ‘s flower showed the existance of steroid, alkaloid, flavonoid, glycoside, tannin, and essential oil. Steroid, flavonoid, and alkaloid substance are the substances that is expected to have the larvicidal effect. Steroid is able to restrict insect’s growth in the transition phase from larvae to pupae and vice versa. Flavonoid works as a respiratory toxin. Alkaloid acts as a contact toxic and inhibits the acetylcholinesterase which will cause a bitter taste which then interrupts the mealtime of the larvae. Meanwhile Artocarpus camansi contains a substances such as saponin, flavonoid, and polyphenol whose effect is lowering the appetite, inhibiting the respiratory system, and inhibiting the moulting hormone. Conclusion: The combination of kamboja flower (Plumeria sp.) and kluwih flower (Artocarpus camansi) has a potential to be used as biolarvacide of Anopheles sp. Keywords: Kamboja, Kluwih, Biolarvacide, Malaria