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All Journal Medula Jurnal Medika Malahayati
Zulhafiz Mandala
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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FAKTOR RISIKO KEJADIAN HEMOROID PADA SUPIR BIS AKAP DI POOL PO. GUMARANG JAYA Yusmanedi Yusmanedi; Zulhafiz Mandala
Jurnal Medika Malahayati Vol 1, No 4 (2014): Volume 1 Nomor 4
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (120.793 KB) | DOI: 10.33024/jmm.v1i4.1936

Abstract

Background: Hemorrhoids is a common disease, and has been there since antiquity, but a lot of people who don’tunderstand even don’t know about the symptoms and complications arising from the disease.Objective: The purpose of the research was to prove whether the food, the incidence of constipation, the type ofphysical activity, family history of hemorrhoids, bowel length is a factor - risk factors on the incidence of hemorrhoids in thedriver Inter-Province (AKAP).Methods: The research is a descriptive research that purpose to identify risk factors for the incidence ofhemorrhoids in the AKAP bus driver at POOL PO. Gumarang JAYA Bandar Lampung.Results: Over a period of 5 years (January 2009 - December 2014) PO Gumarang Jaya has a driver remains of 60people, and obtained a sample of 52 people who met the research criteria. And who have hemorrhoids 78.8%, while 21.2%did not have hemorrhoids, mostly in the age of 30-39 years on average education junior high school graduates, who haveconstipation as much as 73.1% so that the risk of constipation as much as 8,5 times from which isn’t constipation, of asmuch as 78.8% overall driver doesn’t perform physical activity so much risk just as much as 3,226 times, 53.8% ofrespondents come from families with no history of hemorrhoid and has great risk as much as 0,965 times, 71.2% ofrespondents in need time defecate more than 5 minutes so it has a great risk of0.479 times, 78.8% of respondents don’t eatfibrous foods so much risk as much as 0.479 times.
Efektifitas Antibiotik Klindamicin Terhadap Bakteri Propionibacterium Acnes Dengan Metode Difusi Pada Pasien Acne Vulgaris Muhamad Syafei Hamzah; Arief Effendi; Eka Silvia; Anggunan; Ade Utia; Zulhafiz Mandala; Marina Ayu Ningsri; Alvin Andrian Susanto; Muhammad Kevin Wiratama
Medula Vol 12 No 2 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i2.353

Abstract

Acne vulgaris (AV) is defined as a skin disease caused by chronic inflammation of the pilosebaceous unit consisting of non-inflammatory lesions such as open comedones and closed comedones with inflammatory lesions in the form of papules, pustules, and nodules. Tetracycline has a very strong inhibitory power against Propionibacterium acne bacteria. This study aims to compare the effectiveness of the antibiotics clindamycin, benzoyl peroxide, erythromycin, azelac acid and Lactobacillus achidopillus with the effectiveness of tetracycline against Propionibacterium acnes. Research on the effectiveness of tetracycline antibiotics against Propionibacterium acnes was carried out in vitro using the disc diffusion method on Mueller-Hinton Agar media and analyzed the data using Shapiro-wilk for data normality. After being declared to be normally distributed (p>0.05), an unpaired T-test was performed. If the data obtained were not normally distributed, the Mann-Whitney test was performed to test the ratio 1 and 2. The mean effectiveness of tetracycline antibiotics was 48.7 mm and placebo/ vaseline of 0 mm against Propionibacterium acnes in vitro. Based on the unpaired T-Test, Sig.(2-Tailed) = 0.000 (p<0.05) was obtained, which means that there is a significant difference in each variable. There are differences in the effectiveness of Tetracycline antibiotics with placebo/vaseline on the growth of Propionibacterium acnes using the in vitro diffusion method.  
Co-Authors Ade Utia Alvin Andrian Susanto Anggunan Arief Effendi Eka Silvia Marina Ayu Ningsri Muhamad Syafei Hamzah Muhammad Kevin Wiratama Yusmanedi Yusmanedi