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Journal : Jambura Journal of Chemistry

α-Glucosidase Inhibitor Activity of some Indonesian Syzygium Extracts Emma J. Pongoh; Rymond J Rumampuk; Astin Lukum; Ardi Kapahang
Jambura Journal of Chemistry Vol 3, No 2 (2021): August
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jambchem.v3i2.11416

Abstract

The leaves and fruits of Indonesian Syzygium spp such as white pakoba, red pakoba and bombongan have been extracted by ethanol. The ethanolic extract was partitioned with polar solvent gradient using n-hexane, ethyl acetate and n-butanol repeatedly. Each fraction was tested for antidiabetic activity and exhibited varying degrees of antidiabetic activity when tested with α-glucosidase method. Antidiabetic test indicated that the ethyl acetate and butanol fractions of the leaves of pakoba white, red pakoba and bombongan has potential as a source of active compounds.
Isolasi dan Identifikasi Senyawa Fenil Pentanoat dari Fraksi Etil Asetat Sarang Semut (Myrmecodia pendans.) Emma J. Pongoh; Rymond J Rumampuk; Sofia S. Krisen; Hutri C. Werfete; Arfiani Rizki Paramata
Jambura Journal of Chemistry Vol 4, No 2 (2022): August
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jambchem.v4i2.18945

Abstract

Ants nest (Myrmecodia pendans.) is an epiphytic plant from Papua which is used as herbal medicine. The reseacrh to isolate and identification the ethyl acetate fraction of phenyl penatnoate compounds from ant nests(myrmecodia pendans.). The isolaton process was carried out using the maceration technique, fro the purifcation and separation of compounds the thin layer chromatographic and gravity column chromathographic were used F1 isolated were obtained weighing up to 180 mg in liquid. Identification using spectroscopy Nuclear Magnetic Resonance Proton (1H-NMR) and Nuclear Magnetic Resonance Carbon (13-NMR). The result of identification of isolated F1 indicated the posibillity of a phenyl derivative compound with the proposed name 6-hydroxy-5,5-dimethyl-phenyl-pentanoate.