I Ketut Sudiana
Universitas Airlangga

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POLA JUMLAH TROMBOSIT PENDERITA DEWASA TERINFEKSI VIRUS DENGUE DI RSUD DR.SOETOMO SURABAYA Lelyana Sih Afgriyuspita; Hartono Kahar; I Ketut Sudiana
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 1 (2021)
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i1.1365

Abstract

ABSTRACT The trend of dengue viral infection in Indonesia and several countries has changed from children to older age groups. Thrombocytopenia is a common laboratory parameter used to diagnose dengue virus infection that has the possibility to change day by day. This research was expected to improve understanding thrombocyte pattern in adult patients. This was a descriptive study with a retrospective design using medical records of Dr. Soetomo general hospital Surabaya during 2017-2018. The sample used was adult patients in the age range of 18-55 years old with Dengue Fever (DF) or Dengue Haemorrhagic Fever (DHF). The sampling technique was total sampling and obtained 62 samples. Data was analyzed using an independent t-test and Mann-Whitney. The pattern of average thrombocyte count decreased on the 3rd day till the 6th day. Entering the 7th day, it increased but did not reach the normal value. There were significant differences in the average of thrombocyte count between DF and DHF patients during the 4th day (p=0.003), 5th day (p = 0.006) and the 6th day (p= 0.014). Decreased thrombocyte count < 100,000/µL in DHF patients should be intensively observed starting from the 3rd day of illness. Keywords : DF,DHF, thrombocyte,adult
Mutant p53 Expression Of Oral Transformed Epithelium Cell In Rats Injected By Benzo[A]Pyrene Sawitri Dwi indah Pertami; I Ketut Sudiana; Theresia Indah Budhy; Retno Palupi; Ira Arundina
STRADA Jurnal Ilmiah Kesehatan Vol. 9 No. 1 (2020): May
Publisher : Institut Ilmu Kesehatan STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.923 KB) | DOI: 10.30994/sjik.v9i1.234

Abstract

Benzopyrene is a polycyclic aromatic hydrocarbons (PAHs) compound that can cause transformation of normal cells into malignant in order to its genotoxic,mutagenic,and carsinogenic ability. DNA mutation in tumor suppressor genes p53 make cells immortal which results in cell transformation and develops into malignancies. This study consist of five groups including the control group (without benzopyrene injection) and 4 treatment groups injected with benzopyrene each for 4 weeks (P1), 6 weeks (P2), 8 weeks (P3) and 10 weeks (P4). Therefore, the mutant p53 expression was calculated and analyzed statistically with the One Way Anova Test. There was signifficance difference in mutant p53 expression of oral transformed epithelium cell injected by benzopyrene (p=0.000) and the highest expression was at 10th week. It can be concluded that the mutant P53 expression of oral transformed epithelium cells in rats was increased after injected by benzopyrene
Terapi Pijat Mengurangi Kelelahan, Kecemasan dan Gangguan Tidur Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisis Dian Retno Pratiwi; I Ketut Sudiana; Ika Yuni Widyawati
Journal of Telenursing (JOTING) Vol 5 No 2 (2023): Journal of Telenursing (JOTING)
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/joting.v5i2.3336

Abstract

This study aims to examine and review what types of massage therapy can reduce fatigue, anxiety, and sleep disturbances experienced by CRF patients undergoing HD. The method used is a systematic review using five databases, namely Scopus, ScienceDirect, Pubmed, CINAHL, and ProQuest, with publication limits from 2016 to 2021, in English, full-text articles. The keywords used are “massage therapy” AND “fatigue” AND “Anxiety” AND “sleep disorder” OR “sleep quality” AND “Chronic Kidney Disease” AND “hemodialysis.”” The results showed that of the ten articles reviewed, there were types of massage therapy, namely back massage, foot massage, hand massage, and combinations with aromatherapy oils which were known to be more effective in reducing fatigue scores and anxiety and improving sleep quality. This review concludes that massage therapy is an effective, efficient therapy with no side effects for HD patients. However, to do this therapy, it is recommended to take a massage course or training first. Keywords: Sleep Disorders, CRF, Hemodialysis, Anxiety, Fatigue, Massage Therapy