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All Journal Majalah Kedokteran Gigi Indonesia Dental Journal (Majalah Kedokteran Gigi) Indonesian Journal of Dental Medicine
Alexander Patera Nugraha
Department Orthodontics, Faculty Of Dental Medicine, Universitas Airlangga
Dentistry

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Profil Angular Cheilitis pada penderita HIV/AIDS di UPIPI RSUD Dr. Soetomo Surabaya 2014 Alexander Patera Nugraha; Mintarsih Djamhari K; Adiastuti Endah P; Bagus Soebadi; Erwin Asta Triyono; Remita Adya Prasetyo; Sulistyowati Budi
Majalah Kedokteran Gigi Indonesia Vol 1, No 1 (2015): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1036.707 KB) | DOI: 10.22146/majkedgiind.9032

Abstract

Profile of Angular Cheilitis in HIV/AIDS Patients at UPIPI RSUD Dr. Soetomo Surabaya 2014. For over twenty years, human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) have become a significant public health concern, and the epidemic continues to challenge humanity. HIV related oral lesions can be used as markers of the immune status. Angular Cheilitis (AC) which is one of the seven oral manifestations which are strongly associated with HIV Infection, has been identified and internationally calibrated. The purpose of this research is to identify the Angular Cheilitis and its association with reduced Cluster of Differentiation 4 (CD4+) count in HIV/AIDS patients at Unit Perawatan Intermediet Penyakit Infeksi (UPIPI) RSUD Dr. Soetomo Surabaya. This was an Analytic observasional research with cross-sectional and total sampling method. The samples consisted of 88 HIV/AIDS patients treated in UPIPI RSUD Dr. Soetomo Surabaya from July to August 2014. The Diagnosis of Angular Cheilitis was based on clinical appearance; the oral cavities of the research subjects were examined by dentists specialized in Oral Medicine. CD4+ counts were obtained from the patient’s medical record. Eighty Eight HIV/AIDS patients were examined and there were 120 cases of oral manifestation. There were 31 cases of Angular Cheilitis (25,83%). Angular Cheilitis was found to be significantly correlated to the decrease in CD4+ cell count below 200 cells/mm3 (P< -,245). Risk Relative anaylsis concludes that HIV/AIDS patients with Candidiasis Oral 7.5 more often suffer from AC. There is a correlation between AC and OC (p<0,357). Angular Cheilitis may be used as an alternative to predict CD4+ count at field-based settings to diagnose the immunocompromised status of HIV-infected individuals.
Dental Health Status and Knowledge Improvement After Dental Health Empowerment at Elementary School Student in Gresik, East Java Alexander Patera Nugraha; Alida Alida; Dwi Rahmawati
Indonesian Journal of Dental Medicine Vol. 5 No. 1 (2022): January - June
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v5i1.2022.1-4

Abstract

Background: Dental caries is the most common dental and oral health condition. Children's growth and development may be hampered by dental cavities. Furthermore, it may raise the risk of stunting owing to a lack of dietary intake, which may have an impact on quality of life. Oral and dental health empowerment is required to increase dental health knowledge and understanding of dental disorders, particularly during the corona virus disease-19 (COVID-19) pandemic. Objective: to describe oral and dental health knowledge improved following dental health empowerment at Madrasah Ibtidaiyah Miftahul Ulum Elementary School in Melirang, Bungah Distric, Gresik City, East Java. Material and Methods: Three surveyors were responsible for data collecting. This study's sample size was 150 people ranging from fourth to sixth grade. The seminar covered dental and oral health and was provided via teledentistry. The participants were asked to fill out a Google form for the pre- and post-test to determine the improvement of oral and dental health knowledge for the dental health empowerment evaluation. Result: The majority of oral and dental health participants understood the presentation on oral and dental health empowerment. The post-test percentage was higher (93.59%) than the pre-test rate (56.81%). Conclusion: The program findings demonstrated that oral and dental health empowerment via teledentistry was an effective medium for increasing elementary school children's understanding of dental and oral health status.
Level of Knowledge of Clean and Healthy Living Behavior and Screening of Dental Maloclusion to Enhance Quality of Life Related to Dental and Oral Health In Medowo I and II Elementary School Students Dwi Rahmawati; I Gusti Wahju Aju Ardani; Alexander Patera Nugraha
Indonesian Journal of Dental Medicine Vol. 5 No. 1 (2022): January - June
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v5i1.2022.5-7

Abstract

Background: The elementary school period is a golden age for instilling the values of clean and healthy living behaviour (CHLB) and has the potential as an agent of change to promote CHLB in schools, families and communities so as to create quality human resources in the future. Currently children are very vulnerable to dental and oral health, because at that age there is a transition or change of teeth, namely from deciduous teeth to permanent teeth, for that special attention needs to be given to dental and oral health so that the growth and development of teeth can be maintained properly. Purpose: to enhance knowledge of CHLB and screening of dental malocclusion in an effort to improve the quality of life related to dental and oral health. Methods: 116 participants from grades 3-5 elementary school students. Data was collected by means of intraoral examination and filling out pre-test and post-tests questionnaires. Furthermore, an analysis of the frequency distribution data was carried out by mean of statistical analysis. Results: male students had higher caries (59 people) and those who were not caries (4 people), compared to girls (47 people) and those who were not caries (6 people). CHLB knowledge level is good (86.8%), moderate (8.2) low (5%). Conclusion: caries in boys is higher than in girls and all respondents’ knowledge of CHLB is good.
The Effectiveness of Photodynamic Therapy as An Adjunct to Mechanical Debridement in Peri-Implantitis Treatment Agung Sosiawan; Imam Safari Azhar; Devin Elysia Dhywinanda; Jesslyn Jordana; Jennifer Fiona Salim; Alexander Patera Nugraha
Indonesian Journal of Dental Medicine Vol. 5 No. 2 (2022): July - December
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v5i2.2022.62-65

Abstract

 Background: Peri-implantitis is one of many factors that can cause implant failure, with common cases ranging from 1%-47% and the highest incidence ranging from 10.7%- 47.2%. Mechanical debridement (MD) is currently the standard for peri-implantitis treatment. However, MD has limitations in the removal of infected tissue. Moreover, the rough texture of the implant’s surface and bacteria adhesion and colonization increases the difficulty in performing MD. To overcome these limitations, adjunct therapy is needed to increase peri-implantitis treatment effectiveness. One of those adjunct therapies, photodynamic therapy (PDT), is used to destroy bacterial cells and significantly reduce inflammatory cell infiltration around the implant. Purpose: To describe the effectiveness of PDT as an adjunct therapy to MD in periimplantitis treatment through narrative review. Review: PDT is effective in reducing the number of bacteria, plaque index (PI), bleeding on probing (BOP), probing depth (PD), crestal bone loss (CBL), and excessive proinflammatory cytokines (IL-6, IL-1β, TNF-α) in patients. However, the effectiveness of PDT can be influenced by several factors, including patients’ conditions, such as diabetes and smoking habits, types of photosensitizers used, and exposure time. Conclusion: PDT is an effective adjunctive therapy to MD in peri-implantitis treatment since it can improve clinical parameter values, significantly reduce P. gingivalis, and decrease proinflammatory cytokines.
Management of impacted maxillary canine with surgical exposure and alignment by orthodontic treatment Meralda Rossy Syahdinda; Alexander Patera Nugraha; Ari Triwardhani; Tengku Natasha Eleena binti Tengku Ahmad Noor
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p235-239

Abstract

Background: Maxillary canines play a critical point in creating an aesthetic smile as they support the part of facial muscle. Canines are also the second most frequently impacted teeth after the third molars. In some cases, it is possible to retract canines into their correct position by orthodontics treatment. Purpose: This article highlighted a treatment option with surgical exposure, in which a maxillary canine was impacted. It presented gradual steps from pre-surgical to post-surgical orthodontic treatment. Case: A 16 years old female patient referred to Orthodontic Department by Oral Surgeon for pre-surgical orthodontic treatment of her impacted maxillary canine. Case Management: After pre-surgical orthodontic treatment, the impacted canine was surgically exposed by closed technique since open surgical exposure might need excessive removal of the surrounding bone. Traction was given through a gold chain which attached to the palatal surface of the impacted canine. The tooth was ideally positioned with fixed orthodontic appliances. The permanent right maxillary canine was successfully positioned into proper alignment with the remaining teeth. Aesthetic smile was improved. Conclusion: Malocclusion with impacted canine was successfully treated with MBT orthodontic prescription combined with gold chain that can retract the impacted canine into its physiological position and the patient was satisfied with the aesthetic result.
Molecular docking study of Zingiber officinale Roscoe compounds as a mumps virus nucleoprotein inhibitor Viol Dhea Kharisma; Santika Lusia Utami; Wahyu Choirur Rizky; Tim Godefridus Antonius Dings; Md Emdad Ullah; Vikash Jakhmola; Alexander Patera Nugraha
Dental Journal Vol. 56 No. 1 (2023): March 2023
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i1.p23-29

Abstract

Background: Mumps virus (MuV) can trigger severe infections, such as parotitis, epididymo-orchitis, and meningitis. The effectiveness of MuV vaccine administration has been proven, but current outbreaks warrant the development of antivirals against MuV. Zingiber officinale var. Roscoe or ginger is often used as an alternative remedy. Currently, there are no known in vitro or in vivo studies that investigate ginger as an MuV antiviral. Purpose: This study aims to evaluate the antiviral potency of the bioactive compounds in Zingiber officinale var. Roscoe against MuV. Methods: Antiviral activity screening was conducted by druglikeness analysis, antiviral probability, molecular docking, and molecular dynamic simulation. Results: As an antiviral, 6-shogaol from Zingiber officinale var. Roscoe has potency against MuV. It has a good binding affinity and can establish interactions with the binding domain of the target protein by forming hydrogen, Van der Waals, and alkyl bonds. Conclusion: The complex of 6-shogaol_NP was predicted to be volatile but stable for triggering inhibitory activity. However, these results must be proved by in vivo and in vitro approaches to strengthen the scientific evidence.
Co-Authors Adiastuti Endah P Agung Sosiawan Alida Alida Ari Triwardhani Bagus Soebadi Devin Elysia Dhywinanda Dwi Rahmawati Erwin Asta Triyono Imam Safari Azhar Jennifer Fiona Salim Jesslyn Jordana Md Emdad Ullah Meralda Rossy Syahdinda Mintarsih Djamhari K Remita Adya Prasetyo Santika Lusia Utami Sulistyowati Budi Tengku Natasha Eleena binti Tengku Ahmad Noor Tim Godefridus Antonius Dings Vikash Jakhmola Viol Dhea Kharisma Wahyu Choirur Rizky