Muchlis Ramli
Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta.

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Erratum: Comparative study of the two-period of epidemiological analysis of risk factors for breast cancer in Indonesia. Does it change? Ramli, Muchlis; Budiningsih, Setyawati; Ohno, Yoshiyuki; Tjindarbumi, Didid; Sakamoto, Goi; Cornain, Santoso; Prihartono, Joedo; Darwis, Idral; Suzuki, Sadao; Tjahjadi, Gunawan; Wakai, Kenji; Dillon, Drupadi S.; Soetrisno, Esti; Roostini, Endang S.; Watanabe, Susumu
Medical Journal of Indonesia Vol 8, No 3 (1999): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (568.266 KB) | DOI: 10.13181/mji.v8i3.788

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[This corrects the article DOI:10.13181/mji.v8i2.693]
Risk factors in the development of breast cancer among Indonesian women Prihartono, Joedo; Ohno, Yoshiyuki; Budiningsih, Setiawati; Dillon, Drupadi S.; Tjahjadi, Gunawan; Soetrisno, Esti; Hardjolukito, Endang; Tjindarbumi, Didid; Ramli, Muchlis; Darwis, Idral; Sakamoto, Goi; Suzuki, Sadao; Wakai, Kenji; Cornain, Santoso
Medical Journal of Indonesia Vol 8, No 2 (1999): April-June (Special Issue: Breast Cancer)
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (807.21 KB) | DOI: 10.13181/mji.v8i2.692

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[no abstract available]
Histopathologic profile of mastectomy specimens of operable breast cancer cases Roostini, Endang S.; Sakamoto, Goi; Watanabe, Susumu; Ramli, Muchlis; Prihartono, Joedo; Cornain, Santoso; Ohno, Yoshiyuki; Soetrisno, Esti; Tjahjadi, Gunawan; Darwis, Idral; Tjindarbumi, Didid; Budiningsih, Setyawati; Kubo, Nakako
Medical Journal of Indonesia Vol 8, No 2 (1999): April-June (Special Issue: Breast Cancer)
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (746.158 KB) | DOI: 10.13181/mji.v8i2.698

Abstract

[no abstract available]
Epidemiologic risk factors for breast cancer related to menopausal status in Indonesia Watanabe, Susumu; Darwis, Idral; Tjindarbumi, Didid; Tjahjadi, Gunawan; Soetrisno, Esti; Roostini, Endang S.; Suzuki, Sadao; Prihartono, Joedo; Ohno, Yoshiyuki; Budiningsih, Setyawati; Wakai, Kenji; Cornain, Santoso; Kubo, Nakako; Ramli, Muchlis
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.069 KB) | DOI: 10.13181/mji.v4i3.914

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[no abstract available]
Clinicopathological aspects of breast cancer: A joint study between Indonesia and Japan Tjindarbumi, Didid; Ramli, Muchlis; Watanabe, Susumu; Darwis, Idral; Sakamoto, Goi; Cornain, Santoso; Tjahjadi, Gunawan; Soetrisno, Esti; Ohno, Yoshiyuki; Roostini, Endang S.; Prihartono, Joedo; Suzuki, Sadao; Budiningsih, Setyawati; Wakai, Kenzi
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.74 KB) | DOI: 10.13181/mji.v4i3.911

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[no abstract available]
Pilot study of food consumption pattern: Assessment of validity of dietary history method Herman, Susilowati; Ohno, Yoshiyuki; Dillon, Drupadi; Cornain, Santoso; Sakamoto, Goi; Darwis, Idral; Wakai, Kenzi; Prihartono, Joedo; Watanabe, Susumu; Soetrisno, Esti; Ramli, Muchlis; Budiningsih, Setyawati; Suzuki, Sadao; Roostini, Endang S.; Tjindarbumi, Didid; Tjahjadi, Gunawan
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (446.558 KB) | DOI: 10.13181/mji.v4i3.916

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[no abstract available]
Pathological aspects of breast cancer in Indonesian females, emphasizing on the modified W.H.O. classifïcation Tjahjadi, Gunawan; Sakamoto, Goi; Tjindarbumi, Didid; Watanabe, Susumu; Prihartono, Joedo; Ohno, Yoshiyuki; Cornain, Santoso; Soetrisno, Esti; Roostini, Endang S.; Ramli, Muchlis; Darwis, Idral; Budiningsih, Setyawati; Suzuki, Sadao; Kubo, Nakako
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (878.187 KB) | DOI: 10.13181/mji.v4i3.912

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[no abstract available]
Preliminary analysis of nutritional factors in breast cancer Dillon, Drupadi; Herman, Susilowati; Ohno, Yoshiyuki; Prihartono, Joedo; Cornain, Santoso; Sakamoto, Goi; Ramli, Muchlis; Budiningsih, Setyawati; Suzuki, Sadao; Darwis, Idral; Soetrisno, Esti; Wakai, Kenji; Tjahjadi, Gunawan; Tjindarbumi, Didid; Watanabe, Susumu; Roostini, Endang S.
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.043 KB) | DOI: 10.13181/mji.v4i3.917

Abstract

[no abstract available]
Epidemiological analysis of risk factors for breast cancer in Indonesian females Budiningsih, Setyawati; Ohno, Yoshiyuki; Prihartono, Joedo; Ramli, Muchlis; Wakai, Kenji; Cornain, Santoso; Darwis, Idral; Suzuki, Sadao; Tjindarbumi, Didid; Watanabe, Susumu; Tjahjadi, Gunawan; Sakamoto, Goi; Soetrisno, Esti; Roostini, Endang S.
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (757.106 KB) | DOI: 10.13181/mji.v4i3.913

Abstract

[no abstract available]
E-cadherin and NM23HI as metastasis predictors for various degrees of histological malignancy in invasive ductal carcinoma Rustamadji, Primariadewi; Tjarta, Ahmad; Cornain, Santoso; Ramli, Muchlis; Soetrisno, Esti
Medical Journal of Indonesia Vol 20, No 4 (2011): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1660.907 KB) | DOI: 10.13181/mji.v20i4.459

Abstract

Background: This study aims to analyze whether the expressions of E-cadherin and NM23HI can be used as predictors of ductal carcinoma metastasis in various degrees of  malignancies.Methods: Paraffin blocks were obtained from 97 patients with invasive breast ductal carcinoma with malignancy grade 1, 2 and 3 who came to several hospitals in Jakarta and Bandung from 2000 to 2006. Histopathological examinations of hematoxylin eosin slides of primary and secondary tumors were done to  diagnose the degree of histological malignancy and metastasis status. Further, immunohistochemistry staining of E-cadherin, NM23HI and cytokeratin were done followed by scoring according to the number of positive cells and staining intensity. The  associations of E-cadherin and NM23H1 expression with the presence of metastasis and grade of histological malignancy were analyzed.Results: Subjects were 29-75 years old (mean: 48.19 years), with most subjects aged 40–45 years old, with malignancy grade 1, 2 and 3 of 18.56%, 45.36% and 36.1% respectively. There was a significant association between E-cadherin and NM23HI expression in primary tumors. The possibility of invasion and metastasis inhibition by positive E-cadherin and NM23HI was 14 and 11 times respectively compared to those with negative E-cadherin and/ or NM23HI expression. The ROC curve showed that E-cadherin (r= 0.755) and NM23HI (r= 0.827) expressions were strongly associated, sensitive and specific as metastasis markers. However, E-cadherin and NM23HI expression didnot show significant association with histological degree of invasive ductal carcinoma.Conclusion: E-cadherin and NM23HI expressions can be used as invasion and metastasis markers, but cannot be used as  markers for the degree of histological malignancy of invasive ductal carcinoma. (Med J Indones 2011; 20:263-70)Keywords: Breast cancer, E-cadherin, NM23HI