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All Journal Jurnal Kedokteran Brawijaya JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Indonesian Journal of Cardiology ACI (Acta Cardiologia Indonesiana) Journal of Issues in Midwifery Heart Science Journal CRJIM (Clinical and Research Journal in Internal Medicine) Journal of Nursing Science Update Journal of Community Health and Preventive Medicine
Cholid Tri Tjahjono
Brawijaya Cardiovascular Research Center Department Of Cardiology And Vascular Medicine Faculty Of Medicine, Universitas Brawijaya Malang
Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Phase I Cardiac Rehabilitation Intervention In Patients Undergoing Coronary Artery Bypass Grafting Ardhani Galih; Cholid Tri Tjahjono; Ardian Rizal; Heny Martini
Heart Science Journal Vol 3, No 4 (2022): Prevention, Screening dan Rehabilitation : The Back Bone of Quality Care Improve
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2022.003.04.2

Abstract

Patients undergoing coronary artery bypass grafting (CABG) have a risk of postoperative complications that result in prolonged hospitalization and even death. Interventions in the form of phase I cardiac rehabilitation are needed to help speed up the postoperative recovery process and prevent complications after CABG. Although a lot of research has been carried out, it is necessary to conduct further studies of research articles regarding interventions that can be carried out in cardiac rehabilitation programs that are safe and easy to perform in postoperative CABG patients. The purpose of this literature review was to examine safe and effective interventions in phase I cardiac rehabilitation in patients undergoing CABG. The implementation of phase I cardiac rehabilitation in patients undergoing CABG started from the preoperative phase and continued postoperatively until the patient was discharged. Phase I cardiac rehabilitation interventions, both pre and postoperative, consist of education and counselling, physical exercise, breathing exercises, effective coughing exercises, inspiratory muscle training, and chest physiotherapy. The results of this literature review can be used as a basis for determining standard operating procedures for the implementation of phase I cardiac rehabilitation for hospitals that provide CABG services.
A Case Report Improving Quality of Life in Pulmonary Hypertension with Exercise Training Therapy Ni Putu Frida Baskarani; Cholid Tri Tjahjono
Clinical and Research Journal in Internal Medicine Vol. 3 No. 2 (2022): November 2022
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2022.003.02.8

Abstract

Pulmonary hypertension is an increase in pulmonary artery pressure >25 mmHg. This causes some disturbing clinical complaints. The most common causes of pulmonary hypertension are idiopathic and congenital heart disease. ASD (Arterial Septal Defect) is a congenital heart disease that occurs in 1.6 per 1000 live births, with a fairly high life expectancy. However, most people with ASD are not aware of a heart problem before the appearance of a clinically significant disorder. Most patients with ASD with complications of pulmonary hypertension will complain of being easily tired, fainting easily and having difficulty carrying out daily activities, even light activities. Most ASD cases apply shunt closure therapy as the main therapy, but not a few ASD cases cannot be shunted closure because it is a contraindication that can lead to more severe complications, especially with complications of chronic pulmonary hypertension. One of the non-medical therapies used to improve the quality of life of patients with pulmonary hypertension is exercise therapy. This therapy provides a variety of physical exercises that aim to increase the strength of respiratory muscles and extremities. From this case, exercise therapy is able to provide a significant improvement in the quality of life of the patient with an increase in the patient's ability to perform physical activities, as evidenced by the increase in distance traveled when doing the six-minute walk test (SMWT).
Cardiac Rehabilitation to Prevent Rehospitalization in Myocardial Infarction Patients Diah Ivana; Cholid Tri Tjahjono
Clinical and Research Journal in Internal Medicine Vol. 3 No. 2 (2022): November 2022
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2022.003.02.6

Abstract

Introduction. There is mounting evidence that cardiac rehabilitation (CR) based on physical activity has a positive influence on the degree of disability and level of quality of life, in addition to playing an important and beneficial role in modifying morbidity and mortality. Discussion. Patients who have experienced an acute myocardial infarction, are candidates for cardiac rehabilitation as an essential component of their care. Clinical evaluation, optimization of pharmacotherapy, physical training, psychological rehabilitation, evaluation and reduction of coronary disease risk factors, lifestyle modification, and patient education are the components that should be included in comprehensive cardiac rehabilitation. Immediately following the acute phase of a myocardial infarction, the designated team (consisting of a physician, physiotherapist, nurse, psychologist, dietician, and social worker) should begin comprehensive cardiac rehabilitation. This rehabilitation should contain individualized programs that are designed to optimize the patient's physical, psychological, social, and emotional status. It is recommended that the modern model of comprehensive cardiac rehabilitation be started as soon as possible, continued for the required amount of time, properly staged, and individualized depending on the clinical status of the patients. Conclusion. Cardiac rehabilitation after myocardial infarction is an exercise method that could improve the post myocardial infarct patient’s living quality, includes increasing cardiac ejection fraction, exercise tolerance, and physical status. Therefore, it can decrease rate of rehospitalization in patient post myocardial infarct.
Acute Myocardial Infarction in a 25-Years-Old Male: Understanding the Risk and Comprehensive Management Ardhani Galih; Cholid Tri Tjahjono; Sasmojo Widito; Evit Ruspiono
Heart Science Journal Vol 4, No 1 (2023): Optimizing Outcome in Acute Cardiac Care
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.01.8

Abstract

Acute coronary syndrome (ACS) in young adults is a rare entity, yet it occurs. We present a case of a man 25 years old with no history of certain diseases, suddenly come up with ST elevation myocardial infarct. Young patients have different risk factors, clinical features and prognosis as compared to elderly patients. The diagnosis of ACS is also often overlooked in this subset of population. Furthermore, it constitutes an important problem because of the devastating effect of this disease on the more active lifestyle of young adults. This case report was an attempt to look for the risk factors most prevalent in young patients and its management prior and during the hospital stay.
CARDIOVASCULAR DISEASE AMONG ADOLESCENCE IN SMPN 5 MALANG: A CROSS-SECTIONAL SURVEY STUDY Cholid Tri Tjahjono; Fandy Hazzi Alfata; Heny Martini; Indra Prasetya; sawitri satwikajati
Journal of Community Health and Preventive Medicine Vol. 1 No. 1 (2021): JOCHAPM Vol. 1 No. 1 2021
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.636 KB) | DOI: 10.21776/ub.jochapm.2021.001.01.5

Abstract

Cardiovascular disease (CVD) is the leading cause of death in Asia-Pacific, although highly preventable, CVD was the cause of an estimated 9.4 million deaths. It accounted for one-third of all deaths in 2016. Hypertension is one of cardiovascular disease risk factors. Early detection of cardiovascular disease is the main issues to reduce the prevalence of the cardiovascular disease. Adolescence was the population in which the modifiable cardiovascular risk factor firstly developed. In the year 2018, Indonesian Health Ministry discovered that the prevalence of the cardiovascular disease in East Java was 0.2 % higher than national prevalence and Malang as one of the biggest cities in East Java with high population growth, hence early detection of cardiovascular disease become highlight issue. This cross-sectional survey was held in September 2019 at SMPN 5 Malang, which participated by 123 students (75 females and 48 males). Bivariate analysis was done to examine the correlation between each variable, and logistic regression was done to the most influential variable. Seventy-eight per cent of students were sedentary lifestyle with physical activities < 300 minutes/week, 16.2 % of students were an active smoker, and all were male. Among 123 students, 0.8 % with no cardiovascular risk factor, 29.2 % had 1 risk factor, 30.8 % had 2 risk factors, 27.6 % had 3 risk factors, and 11.3 % had 4 risk factors. The most prevalent risk factors were sedentary life (80 %), increase waist circumference (50 %), passive smoker  (48.5 %), overweight & obesity (15 %), and active smoker (14,6 %). Waist circumference above normal was more prevalent in female (65 %) than male (31%). Hypertension had been found in 14.6 % of students and had a significant correlation with heart rate (p 0.011)
Arterial Stiffness as A Predictor of Future Cardiovascular Events: Methods of Measurement and Clinical Implications Ardani Galih; Cholid Tri Tjahjono; Mohammad Saifur Rohman; Novi Kurniningsih
Heart Science Journal Vol 4, No 2 (2023): Dealing with the Complexity of the Wide Spectrum of Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.02.2

Abstract

Arterial stiffness has recently emerged as strong predictor of cardiovascular events, including coronary heart disease. The cardio-ankle vascular index (CAVI) is a novel index that measures the overall stiffness of the artery all the way from the point where it branches off from the aorta to the ankle. CAVI's ability to provide accurate results regardless of the patient's blood pressure at the moment of measurement is without a doubt its most valuable characteristic. CAVI is related to many cardiovascular risk factors, including hypertension, diabetes mellitus, dyslipidemia, and smoking. It also increases with age and in many arteriosclerotic diseases, such as coronary artery disease, carotid arteriosclerosis, chronic kidney disease, and cerebrovascular disease. CAVI also increases in patients who have cerebrovascular disease. Controlling conditions such as diabetes mellitus and hypertension, in addition to quitting smoking, may also reduce the risk of CAVI. This indicates that CAVI is a physiological surrogate measure of atherosclerosis, and it also implies that it might be a signal of lifestyle change. Recent research has shown that CAVI and numerous functions of the left ventricle are linked to one another, which points to a linkage between the heart muscle and vascular function. This study discusses the fundamentals of CAVI as well as our present understanding of the measurement, with a particular emphasis on its functions and potential future use.  
Effect Of Combination Decafeinated Green Tea and Green Coffee In Reducing Cholesterol Levels In Patients With Metabolic Syndrome Fandy Hazzy Alfata; Mohammad Saifur Rohman; Tri Astiawati; Cholid Tri Tjahjono; Heny Martini
Heart Science Journal Vol 4, No 3 (2023): The Essensial Role of the Metabolic Syndrome in the Development of Cardiovascula
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.03.4

Abstract

Background: Green tea and green coffee are natural ingredients that improve cholesterol levels. Combining the two in experimental animal studies provides more significant benefits when compared to single administration in reducing cholesterol levels.Objective: This study aimed to determine the effect of decaffeinated green tea and green coffee as adjuvant treatments in reducing blood cholesterol levels.Methods: This randomized controlled trial included 90 metabolic syndrome patients determined according to the IDF criteria for Asian people aged 50–70. All subjects received atorvastatin 20 mg and were divided into three groups. Participants in Group 1 received decaffeinated green tea and green coffee 2.5 grams twice daily, Group 2 received 5 grams daily, and Group 3 received a placebo. The total cholesterol, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride levels were measured at the beginning and the end of the study.Results: At 90 days, after administration of the extract of decaffeinated green tea and green coffee, we found that the concentration of total cholesterol in Group 1 and Group 2 was significantly reduced compared to the placebo (-50 ± 6.1 vs. -62.8 ± 5.9 vs. -22.5 ± 5.8 mg/dL; p= <0.05). But there was no significant difference in reduction of total cholesterol levels between the first and second groups. The other parameters also decreased, but not significantly compared to the placebo group.Conclusion: Administration of a combination of decaffeinated green tea extract and green coffee as an adjunctive therapy can reduce the average total  cholesterol, LDL, HDL, and triglyceride levels more than placebo, but only total cholesterol has a significant difference compared to other cholesterol  components.
Correlation Between Smoking and Il-1 Level and Arterial Stiffness as Measured By Cavi in the Young Adult Population Without other Cardiovascular Risk Factors. Ardani Galih Prakosa; Cholid Tri Tjahjono; Novi Kurnianingsih; Djanggan Sargowo; Setyasih Anjarwani
Heart Science Journal Vol 4, No 3 (2023): The Essensial Role of the Metabolic Syndrome in the Development of Cardiovascula
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.03.5

Abstract

Background: Recent studies have shown that arterial stiffness is a strong predictor of cardiovascular events and all-cause mortality, with CAVI (Cardio-Ankle Vascular Index) as a non-invasive arterial stiffness testing method indaily practice.Objective: This study was conducted to examine the relationship between smoking -as a risk factor for arterial stiffness- and CAVI values, as well as levels of IL-1β (Interleukin 1β) as a cytokine that plays a role in the pathophysiology of arterial stiffness.Methods: Eighty-four participants, including smokers and non-smokers without other cardiovascular risk factors, were included in the study. Demographic data, medical history, and smoking behavior were taken using a questionnaire, then IL-1β and CAVI levels were examinedResults: The mean level of IL-1β in smoking subjects was significantly higher (15.09 ± 0.48) than in non-smoking subjects (5.53 ± 0.79; p=0.001). CAVI values in smoking subjects were also significantly higher (8.0 ± 0.06) than in non-smoking subjects (6.9 ± 0.02; p=0.001). Further analysis showed a strong positive correlation between smoking and IL-1β levels (r=+0.776; p=0.001) and CAVI values (r=+0.759; p=0.001).Conclusion: This study shows that smoking significantly correlates with IL-1β levels and CAVI values. The greater number of cigarettes used per day and the longer duration of smoking, there was a positive correlation between IL-1β levels and arterial stiffness as measured by CAVI.
Benefits of Low Dosage of Colchicine Administration on Decreasing Rehospitalization and Mortality within 30 Days in Post-Acute Coronary Syndrome Patients with ST-Segment Elevation Undergoing Percutaneous Coronary Intervention Budi Satrijo; Yordan Wicaksono Ashari; Mohammad Saifur Rohman; Setyasih Anjarwani; Cholid Tri Tjahjono
Heart Science Journal Vol 4, No 3 (2023): The Essensial Role of the Metabolic Syndrome in the Development of Cardiovascula
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.03.6

Abstract

Background: The role of inflammation in myocardial infarction and post-infarction MI remodeling has become a concern for the development of treatment in the last decade. Colchicine can prevent increased inflammation during acute injury.Objective: This study focused on the role of colchicine as an on-top medical treatment, hoping it can reduce mortality and short-term rehospitalization in patients with STEMI.Methods: 347 AMI patients (18-80 year old adults) who visited RSUD dr. Saiful Anwar Malang, between February 2022 and January 2023, participated in this prospective, randomized, double-blinded, placebo-controlledexperiment. Patients were split into two groups and given either a placebo or  colchicine 0.5 mg daily for a month. Standard medical therapy was administered concurrently to both groups as an approachable guideline. The study endpoints were mortality and rehospitalization rates.Result: After one month of follow-up, there was a reduction in rehospitalization due to cardiovascular causes (2 [1.3%] vs. 4 [2.7%], HR 3.42 [1.36-8.56], p<0.05), which was significant in the treatment group compared to the control group. Also, there was a reduction in all-cause mortality, but not statistically significant (2 [1,3% v 3 [2,0%], HR 3,38 [0,53-7,48], p>0,05). In the treated group, there was also a lower non-cardiovascular rehospitalization rate compared to placebo, but not significant (4 [2.6%] vs. 7 [4.7], HR 0.42 [0.15-1.02], p<0.05).Conclusion: The administration of low-dose colchicine for one month has shown benefits in reducing rehospitalization in patients with STEMI who receive PCI therapy.
Co-Authors Adhika Prastya Wikananda Aditya Reza Pratama Adriyawan Widya Nugraha Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Ardani Galih Ardani Galih Prakosa Ardhani Galih Ardhani Galih Ardian Rizal Ardian Rizal Arif Wicaksono Aris Munandar ZI Ayu Asri Devi Adityawati Ayu Asri Devi Adityawati Bambang Rahardjo Budi Satrijo Budi Satrijo Budi Satrijo Budi Satrijo Budi Satrijo Budi Satrijo Dadang Hendrawan David Rubiyaktho Dedy Irawan Diah Ivana Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Dwi Adi Nugroho Dyah Ayu Ikeningrum Ema Pristi Yunita Ema Pristi Yunita, Ema Pristi Evit Ruspiono Evit Ruspiono Fahmy Rusnanta Fandy Hazzi Alfata Fandy Hazzy Alfata Hendrawati Hendrawati Heny Martini Heny Martini Heny Martini Heny Martini Heny Martini Hidayanti, Puji Astuti Nur Idris Idham Imelda Krisnasari Indra Prasetya Indra Prasetya Indriani, Anin Iskandar Iskandar Liemena Harold Adrian Mifetika Lukitasari Mohammad Ryan Ramadhan Mohammad Saifur Rohman Mohammad Saifur Rohman Mohammad Saifur Rohman Monika Sitio Muchammad Dzikrul Haq Karimullah Muhammad Abusari Muhammad Munawar Muhammad Rizki Fadlan Muhammad Rizki Fadlan Muhammad Rizki Rizki Fadlan Ni Putu Frida Baskarani Novi Kurnianingsih Novi Kurnianingsih Novi Kurnianingsih Novi Kurnianingsih Novi Kurnianingsih Novi Kurniningsih Oktafin Srywati Pamuna Olivia Handayani Pawik Supriadi Puji Astuti Nur Hidayanti Ratna Pancasari RWM Kaligis Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito sawitri satwikajati Seprian Widasmara Setyasih Anjarwani Setyasih Anjarwani Setyasih Anjarwani Setyasih Anjarwani Tonny Adriyanto Tri Astiawati Valerina Yogibuana Swastika Putri Valerinna Yogibuana Swastika Putri Wira Kimahesa Anggoro Yoga Waranugraha Yordan Wicaksono Ashari Yusuf Arifin Zulhaidah A, Maimun