Agustina Dwi Retno Nurcahyanti
Program Studi Farmasi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Katolik Indonesia Atma Jaya, Jakarta

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Journal : Jurnal Teknologi Dan Industri Pangan

Fuconxanthin as Antiobesity Agustina D. R. Nurcahyanti; Kris H Timotius
Jurnal Teknologi dan Industri Pangan Vol. 18 No. 2 (2007): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

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Abstract

Fucoxanthin is a member of pigment of xantophlly-carotenoid and a major pigment found in some brown algae. Studies about this pigment revealed the advantages of fucoxanthin as active biological component. One of them is a antiobesity activity. The mechanism of this activity was discribed as increasing UCP1 protein expression in white adipose tissue. increasing UCP1 protein expression associated with thermogenesis process which lead the releasing energy carries fatty acids to out of membrane and converted as converted as het. In addition, fucoxanthin can lead liver to produse DHA although the mechanism was not understood clearly. Antiobesity activity of fucoxanthin direct to create the new nTURl aupplement which low in side effects. Key word : antiobesity, fucoxanthin, Uncoupling Protein (UCP)
AKTIVITAS ANTIOKSIDAN DAN ANTIBAKTERI EKSTRAK POLAR DAN NON POLAR BIJI SELASIH (Ocimum sanctum Linn) [Antioxidant and Antibacterial Activities from Polar and Non Polar Basil (Ocimum sanctum Linn) Seed Extracts] Agustina D. R. Nurcahyanti; Lusiawati - Dewi; Kris H. Timotius
Jurnal Teknologi dan Industri Pangan Vol. 22 No. 1 (2011): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

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Abstract

The aims of this study were to determine total phenolic content, antioxidant activity and antibacterial activity of polar and nonpolar extracts of basil (O. sanctum L.) seed. Seeds of basil (O. sanctum L.) were extracted using a soxhlet extractor using four types organic solvent, i.e. chloroform, ethyl acetate, acetone, and methanol for eight hours each. The total phenolic content was determined using Folin Ciocalteu method, antioxidant activity was determined using reducing power and DPPH (1,1-diphenyl,2-picrylhydrazyl) scavenging activity methods, while antibacterial activity was tested using agar diffusion method. The result showed that the highest total phenolic content and antioxidant activity was obtained in methanol extract with 3.63 ± 0.21 mgGAE/g phenolic total, 58.39 ± 3.81 mek/g using reducing power method and 85.73 ± 0.86% free radical scavenging activity. Furthermore the result of antibacterial activity testing showed that the highest diameter of inhibition zone was observed in ethyl acetate extract inhibition on E.coli, P.aeruginosa, B.subtilis, and S.aureus where its inhibition zone were 13.53 ± 0.63; 10.67 ± 1.05; 14.93 ± 0.80, and 13.46 ± 0.79 mm, respectively. This result suggests that both polar and nonpolar basil seed extracts possess specific biological activity. This data provide valuable and strong database for exploration of natural antibacterial agents and antioxidant for food and health industry application.