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Endang S. Roostini
Department of Anatomic Pathology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta 10430.
Medicine & Pharmacology

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Breast cancer case control study: Conceptual framework and epidemiological study design Prihartono, Joedo; Ohno, Yoshiyuki; Budiningsih, Setyawati; Suzuki, Sadao; Cornain, Santoso; Kubo, Nakako; Tjindarbumi, Didid; Watanabe, Susumu; Tjahjadi, Gunawan; Sakamoto, Goi; Darwis, Idral; Soetrisno, Esti; Roostini, Endang S.
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.949 KB) | DOI: 10.13181/mji.v4i3.910

Abstract

[no abstract available]
Clinicopathological aspects of breast cancer: A joint study between Indonesia and Japan Tjindarbumi, Didid; Ramli, Muchlis; Watanabe, Susumu; Darwis, Idral; Sakamoto, Goi; Cornain, Santoso; Tjahjadi, Gunawan; Soetrisno, Esti; Ohno, Yoshiyuki; Roostini, Endang S.; Prihartono, Joedo; Suzuki, Sadao; Budiningsih, Setyawati; Wakai, Kenzi
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.74 KB) | DOI: 10.13181/mji.v4i3.911

Abstract

[no abstract available]
Pilot study of food consumption pattern: Assessment of validity of dietary history method Herman, Susilowati; Ohno, Yoshiyuki; Dillon, Drupadi; Cornain, Santoso; Sakamoto, Goi; Darwis, Idral; Wakai, Kenzi; Prihartono, Joedo; Watanabe, Susumu; Soetrisno, Esti; Ramli, Muchlis; Budiningsih, Setyawati; Suzuki, Sadao; Roostini, Endang S.; Tjindarbumi, Didid; Tjahjadi, Gunawan
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (446.558 KB) | DOI: 10.13181/mji.v4i3.916

Abstract

[no abstract available]
Pathological aspects of breast cancer in Indonesian females, emphasizing on the modified W.H.O. classifïcation Tjahjadi, Gunawan; Sakamoto, Goi; Tjindarbumi, Didid; Watanabe, Susumu; Prihartono, Joedo; Ohno, Yoshiyuki; Cornain, Santoso; Soetrisno, Esti; Roostini, Endang S.; Ramli, Muchlis; Darwis, Idral; Budiningsih, Setyawati; Suzuki, Sadao; Kubo, Nakako
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (878.187 KB) | DOI: 10.13181/mji.v4i3.912

Abstract

[no abstract available]
Preliminary analysis of nutritional factors in breast cancer Dillon, Drupadi; Herman, Susilowati; Ohno, Yoshiyuki; Prihartono, Joedo; Cornain, Santoso; Sakamoto, Goi; Ramli, Muchlis; Budiningsih, Setyawati; Suzuki, Sadao; Darwis, Idral; Soetrisno, Esti; Wakai, Kenji; Tjahjadi, Gunawan; Tjindarbumi, Didid; Watanabe, Susumu; Roostini, Endang S.
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.043 KB) | DOI: 10.13181/mji.v4i3.917

Abstract

[no abstract available]
Epidemiological analysis of risk factors for breast cancer in Indonesian females Budiningsih, Setyawati; Ohno, Yoshiyuki; Prihartono, Joedo; Ramli, Muchlis; Wakai, Kenji; Cornain, Santoso; Darwis, Idral; Suzuki, Sadao; Tjindarbumi, Didid; Watanabe, Susumu; Tjahjadi, Gunawan; Sakamoto, Goi; Soetrisno, Esti; Roostini, Endang S.
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (757.106 KB) | DOI: 10.13181/mji.v4i3.913

Abstract

[no abstract available]
The immunohistopathological features of prurigo Hebra Boediardja, Siti A.; Tjarta, Achmad; Cornain, Santoso; Budimulja, Unandar; Djuanda, Adhi; Roostini, Endang S.; Hartati, Meny
Medical Journal of Indonesia Vol 10, No 1 (2001): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1308.599 KB) | DOI: 10.13181/mji.v10i1.1

Abstract

Until now the pathologic mechanisms of prurigo Hebra (PH) is still understood. Earlier study the genetic inheritance of PH showed the multifactorial pattern. Considering the genetic inheritance and the existence of allergic reaction to insects bite in all patients, might be the mechanisms followed hypersensitivity reactions. The purpose of this study is to evaluate the general and specific local inflammatory features of early and late lesions of prurigo Hebra (PH). Fifty biopsy specimens of early and late lesions of prurigo Hebra patients were processed with haematoxylin-eosin (HE) and immunoperoryde (lP) staining using monoclonal antibodies against specific inflammatory cells namely B cells, T cells, helper T (CD4+) cells, supressor T (CD8+) cells, Langerhans cells, and antigen presenting cells (APC) that expressed HLA-DR antigen. HE-stained specimens: In early lesions, PMN cells were few, while eosinophils were present in great quantity and independent of mast cells and plasma cells; this feature was similar to that of insect bite reaction. IP-stained specimens: In late lesions, the amounts of lympho-histiocytic infiltration consisting of T cells, CD8+ cells, HLA-DR-expressing APCs were greater than those of early lesions, although it was not statistically significant. An exception was for the CD4+ cells, whose number in early lesions was significantly higher. The ratio of CD4+ to CD8+ in early lesions was higher than in late lesions (3/1: 2/1). This suggested that CD4+ cells were predominant. B cells, which were normally absent, appeared in small quantity in both early and late Lesions. The presence of B cells was not statistically correlated with T cells or eosinophils. The number of Langerhans cells in late lesions was higher than in early lesions. There was a strong correlation (r=0.39) between T cells and HLA-DR-expressing antigen-presenting cells (APCs/HLA-DR). Those cells found in great qunntity suggested that PH patients usually expose to extrinsic factors. In some cases with severe condition, the presence of eosinophils was more profound and was statistically significant. It is conclude that  immunohistopathological mechanisms of PH follow the mixed types (one and IV) hypersensitivity reaction. (Med J Indones 2001;10:1-15)Keywords: Prurigo Hebra, eosinophils, CD4+cells, mixed (I and IV) types of hypersensitivity.
Co-Authors Achmad Tjarta Adhi Djuanda Didid Tjindarbumi Drupadi Dillon Drupadi S. Dillon Esti Soetrisno Goi Sakamoto Gunawan Tjahjadi Idral Darwis Joedo Prihartono Kenji Wakai Kenzi Wakai Meny Hartati Muchlis Ramli Nakako Kubo Sadao Suzuki Santoso Cornain Setyawati Budiningsih Siti A. Boediardja Susilowati Herman Susumu Watanabe Unandar Budimulja Yoshiyuki Ohno