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All Journal Saintia Biologi BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Majalah Kedokteran Nusantara The Journal Of Medical School Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Majalah Patologi Indonesia IJOEP : International Journal of Ecophysiology
Emita Sabri
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Journal : Saintia Biologi

 1 
KELAINAN PERKEMBANGAN KRANIOFACIAL FETUS MENCIT (Mus musculus L.) Strain DDW SETELAH PEMBERIAN EKSTRAK N-HEKSAN BUAH ANDALIMAN (Zanthoxylum acanthopodium DC.) Mai Sarah; Emita Sabri; Salomo Hutahaean
Saintia Biologi Vol 1, No 1 (2012)
Publisher : Saintia Biologi

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Abstract

The purpose of this study is  to investigate the effect of n-hexane extract of andaliman (Zanthoxylum acanthopodium DC.) fruit on craniofacial development of DDW Mice (Mus musculus L.). Experiment was carried out using Completely Randomized Design (CRD) with 5 treatments and 6 replicates. Treatments  consist  of a blank control, vehicle control (1% CMC) and 3 concentrations of andaliman extract (2%, 4% and 6%). All treatments were administered by oral gavage (0.1 ml/10 g bw) once  daily from day 0 to day 10 of gestation.  N-hexane extract of andaliman fruit induced developmental abnormalities in craniofacial structures i.e. increased the incidence of microphthalmia (P <0.05), and hydrocephalus (P <0.05). In conclusion, we suggested that andaliman fruit may have fetotoxic effects.   Keyword: andaliman (Zanthoxylum acanthopodium DC.), micropthalmia, hydrocephalus
GAMBARAN HISTOLOGIS HEPAR MENCIT (Mus musculus L.) STRAIN DDW SETELAH PEMBERIAN EKSTRAK N-HEKSAN BUAH ANDALIMAN (Zanthoxylum acanthopodium DC.) SELAMA MASA PRA IMPLANTASI DAN PASCA IMPLANTASI Eka Prasetiawan; Emita Sabri; Syafruddin Ilyas
Saintia Biologi Vol 1, No 1 (2012)
Publisher : Saintia Biologi

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Liver histological features of DDW mice (Mus musculus L.) treated with n-hexane extract of Andaliman (Zanthoxylum acanthopodium DC.) fruit during pre- and post-implantation has been studied in Laboratory of Animal Structure, Department of Biology, Faculty of Mathematics and Natural Science, University of Sumatera Utara, Medan. Experiment used completely randomized design (CRD) consisted of 2 periods of treatment: pre-implantation (day 0-3; group A) and post-implantation (day 6-14; group B). For each group,  mice were treated daily by oral gavage with 0, 1, 2, 4, or 6 % of andaliman extract in 0.3 ml of 1% CMC. The result showed, liver in treatment groups was pale and showed mottled surface texture. Hepatocyte damage in post-implantation group was higher than in pre implantation group (p> 0.05). We concluded that n-hexane extract of andaliman fruit appears to negatively affect liver histology of mice. Keywords: liver histology, andaliman (Zanthoxylum acanthopodium DC.),  post implantation, pre implantation
PENGARUH BUAH TERONG BELANDA (Solanum betaceum Cav.) TERHADAP JUMLAH ERITROSIT DAN KADAR HEMOGLOBIN MENCIT JANTAN (Mus musculus L.) ANEMIA STRAIN DDW MELALUI INDUKSI NATRIUM NITRIT (NaNO2) Sister Sianturi; Masitta Tanjung; Emita Sabri
Saintia Biologi Vol 1, No 2 (2013)
Publisher : Saintia Biologi

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The effect  of  terong belanda (Solanum betaceum Cav.) juice on anemia mice DDW strain induced by sodium nitrite has been studied from March 2012 to August 2012 in the Laboratory of Animal Physiology and Laboratory of Tissue Culture, Department of Biology, Faculty of Mathematics and Natural Science, University of Sumatera Utara, Medan. This research performed with completely randomized design and was divided in two controls and three treatments. The treatments were divided into three classes concentration of juice such as: 40% (P1), 50% (P2), and 60% (P3) respectively. Each class consisted of six animals. The juice was given orally 0.3ml/day. Results indicated that juice of terong belanda in anemia male mice showed no significantly increased  in the number of erythrocytes if compared to either the anemia control or blank control, but significantly increased  in haemoglobin levels if compared to anemia control.   Keywords : erythrocytes, haemoglobin, Mus musculus, sodium nitrit, terong belanda
PENGARUH EKSTRAK SEGAR DAUN ROSELA (Hibiscus sabdariffa L.) TERHADAP JUMLAH ERITROSIT DAN KADAR HEMOGLOBIN MENCIT JANTAN (Mus musculus L.) ANEMIA STRAIN DDW MELALUI INDUKSI NATRIUM NITRIT (NaNO2) Asmitra Sembiring; Masitta Tanjung; Emita Sabri
Saintia Biologi Vol 1, No 2 (2013)
Publisher : Saintia Biologi

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Abstract

The purpose of this research is to investigate the effect of fresh leave extract of rosela (Hibiscus sabdariffa L.) on erythrocyte and haemoglobin concentration in anemia male mice (Mus musculus L.) DDW strain induced by sodium nitrite. Completely randomized design (CRD) was used in this experiment, consisting of 5 groups. The first two groups is control induced by NaNO2 for 18 days and the second group is induced by NaNO2 for 18 days and then distilled water for 14 days, and three groups of teratment. The treatment group, divided into three classes of concentration such as; 14 mg/ml (P1), 28 mg/ml (P2) and 42 mg/ml (P3). The treatment group induced by NaNO2 first for 18 days and then healing process by extract of rosela leaves for 14 days. Each class consisted of six experiments animals. The extract was given orally     0.3 ml/day.  The results indicate that leave extract affect on increasing of erythrocytes and hemoglobin concentration that have a significantly different (p<0.05) between control and  treatments.   Keyword: anemic, erythrocytes, haemoglobin, rosela leaves.
Co-Authors Asmitra Sembiring Delyuzar dr Delyuzar, Delyuzar Eka Prasetiawan Elimasni Mai Sarah Masitta Tanjung Melvariani Syari Batubara, Melvariani Syari Nursahara Pasaribu Salomo Hutahaean Sister Sianturi Suci Rahayu Sufitni Supriharti, Denny Syafruddin Ilyas