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Kadar Amoniak Darah Pasien Sirosis Hati dengan Ensefalopati Hepatik Minimal Arnelis Arnelis; Andri Kurniawan; Nasrul Zubir; Saptino Miro; Vesri Yoga
Majalah Kedokteran Andalas Vol 45, No 2 (2022): Online April 2022
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v45.i2.p167-172.2022

Abstract

Ensefalopati Hepatik (EH) merupakan sindrom neuropsikiatri yang dapat terjadi pada penyakit hati akut dan kronik berat. Penelitian ini bertujuan untuk mengetahui kadar amoniak pasien sirosis hati dengan ensefalopati hepatick minimal pasien. Hasil penelitian menunjukkan bahwa dari 43 pasien yang diteliti, didapatkan 3(6,98%) pasien dengan kadar amoniak darah berada dalam nilai normal, sedangkan 40(93,02%) pasien mengalami peningkatan. Nilai amoniak paling tinggi didapatkan 67 µg/dL.  Dari penelitian ini dapat ditarik kesimpulan bahwa pada pasien sirosis dengan EHM terjadi peningkatan kadar ammonia darah.
Helicobacter pylori in dyspeptic patients in M. Jamil Hospital-Padang Nasrul Zubir; Dona Elfina; Julius R. Samban
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 1, NUMBER 1, December 2000
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/1120005-8

Abstract

Objective: Helicobacter pylori infection is probably the most common infection caused by pathogenic bacteria and affects more than half of the world population. These bacteria caused many gastroduodenal pathology such as chronic active gastritis, peptic ulcer and gastric malignancy. This study investigated Helicobacter pylori infections in dyspeptic patients. Materials Methods: Forty dyspeptic patients were examined using upper gastrointestinal endoscopy and biopsy for histopathologic examination. Results: The symptom of the dyspeptic patients were epigastric tenderness (100%). Endoscopic abnormalities were found in 39 (97.5%) cases. The gastric abnormalities were chronic antral gastritis in 24 (60%), esophagitis and gastritis in 7 (17.5%), and gastric ulcer in 3 (7.5%). Twenty four out of 40 patients had anti-Helicobacter pylori positive (60%) and histopathologic examination were positive 18 (45%). The histopathologic examination found atrophy in 18 (45%), MN in 18 (45%), PMN in 18 (45%), and metaplastic in 4 (10%). Conclusion : The prevalence of Helicobacter pylori in dyspeptic patients were 60% (serology) and 45% (histopathology).  Keywords: Helicobacter pylori, dyspeptic, serology, histopathology