Amung Logam Saputro
Departemen Klinik Veteriner, Fakultas Kedokteran Hewan, Universitas Airlangga

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Pengaruh Ekstrak Daun Sukun (Artocarpus altilis) Terhadap Kepadatan Kolagen dalam Proses Penyembuhan Luka Eksisi Tikus Putih (Rattus norvegicus) Rizka Wulan Cahya; Ira Sari Yudaniayanti; Prima Ayu Wibawati; Maya Nurwartanti Yunita; Nusdianto Triakoso; Amung Logam Saputro
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Faculty of Veterinary Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (679.313 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.25-30

Abstract

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh ekstrak daun sukun (Artocarpus altilis) terhadap kepadatan serabut kolagen dalam penyembuhan luka eksisi pada tikus putih (Rattus norvegicus). Dua puluh ekor tikus jantan dibagi secara acak menjadi lima kelompok, terdapat kontrol negatif (K-) yang diberikan basis salep, kontrol positif (K+) yang diberikan povidone iodine 10%, kelompok perlakuan (P1, P2, P3) yang diberikan salep ekstrak daun sukun 6,25%; 12,5%; dan 25%. Terapi diberikan sekali sehari selama empat belas hari. Hasil uji nonparametrik Kruskal-Wallis menunjukkan perbedaan nyata (p<0,05) dan dilanjutkan dengan uji Mann-Whitney. kelompok kepadatan kolagen P1, P2, dan P3 tidak berbeda nyata (p>0,05), tetapi berbeda nyata dengan kelompok K- dan K+. Kesimpulan dari penelitian ini adalah ekstrak daun sukun efektif untuk meningkatkan kepadatan kolagen dalam proses penyembuhan luka eksisi.
The Potentials of Robusta Coffee Seed Extract as Antioxidant on Kidney Histopathology in Mice Exposed to Monosodium Glutamate: Potensi Pemberian Ekstrak Biji Kopi Robusta sebagai Antioksidan Terhadap Gambaran Histopatologi Ginjal Mencit yang Dipapar Monosodium Glutamat Feby Dwi Wisudawati; Nove Hidajati; Faisal Fikri; Kuncoro Puguh Santoso; Amung Logam Saputro; Muhammad Thohawi Elziyad Purnama
Veterinary Biomedical and Clinical Journal Vol. 5 No. 1 (2023)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2023.005.01.3

Abstract

The purpose of this study was to determine the potential of administration robusta coffee extract as an antioxidant on the renal histopathology in mice exposed to monosodium glutamate (MSG) orally. This study used 20 adult male rats with Balb C strain divided into 5 experimental groups, namely K + (MSG 0.12 mg / head and Vitamin C 6 mg/mice), K- (MSG 0.12 mg/mice and Sodium carboxymethyl cellulose (CMC Na) 0,1 ml/mice), P1 (MSG 0.12 mg/mice and Robusta coffee extract 0.1 mg/mice), P2 (MSG 0.12 mg/mice and Robusta coffee extract 0.2 mg/mice), and P3 (MSG 0.12 mg/mice and 0.4 mg Robusta coffee extract mg/mice). The experimental group was treated every day at intervals between MSG and Vitamin C, CMC Na, and Robusta coffee extract for 60 min, the treatment was carried out for 42 days. Kidney histopathology scores were analyzed using the Saphiro-Wilk and Levene test to evaluate homogeneity, followed by the Kruskal Wallis test. The results of the Saphiro Wilk and Levene statistical analysis obtained p<0.05, thus the data continued with the Kruskal Wallis test scores of kidney cell damage obtained 0.043 which showed that the data were significant. The mean score of kidney cell damage in the treatment groups was K+ 1.60; K- 1.63; P1 1.70; P2 1.63; and P3 1.73. The conclusion is that Robusta coffee bean extract did not show a decrease in kidney cell damage that was different between treatment groups. Further research is needed to find out about the effect of different dosages of Robusta Coffee Extract to different organs