The Purpose of this study was to determine the effecet of interest rate and inflation on stock prices, by taking sample of the tourism sub-sector companies listerd on the Indonesian Stock Exchange 2015-2019 period. The sampling technique used in this study using judgment sampling as many as 22 companies engaged in the sector. Data collection method using secondary data processing. This study uses a quantitative approach using multiple linear regression analysis, with the aim of knowing the direction and how much influence the independent variable has on the dependent variable. From the results of data processing, it is known that the partial test results of Interest rate (X1) has a negative and significant effect on stock prices (Y) with a regression coefficient value of -38.43 and Inflation (X2) have a negative and insignificant effect on stock prices (Y) with a regression coefficient of -2.219