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Fitri Maya Sari
Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang
Medicine & Pharmacology

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Efek Diuretik dan Daya Larut Batu Ginjal Dari Ekstrak Daun Mangkokan (Nothopanax scutellarium. Merr) Elisma Elisma; Fitri Maya Sari; Helmi Arifin
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.941 KB) | DOI: 10.52689/higea.v2i1.26

Abstract

Research on the effects of diuretics and solubility of kidney stones of Mangkokan leaf (Nothopanax scutellarium Merr.) extract has been done. Testing the solubility of kidney stones performed on 4 groups of test animals, namely the control group (without extract), The treatment dose groups of 0.5%, 1%, and 2%. Level of kidney stones are dissolved in the control group, 0.5%, 1% and 2% are 0.00521%, 0.01232%, 0.02433% and 0.05669% respectively. These result indicate a difference in dissolving kidney stones. Diuretic effect tested on 15 white male rats were divided into 5 groups of tests, one positive control group (furosemide), 1 negative control group (tween 80 1%), 3 treatment groups (doses of 125; 250 and 500 mg/kg BW). The result showed that all of three doses of extract have diuretic effect.
Co-Authors Elisma Elisma Helmi Arifin