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All Journal JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Farmasi Higea

Elisma Elisma

Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang

Author-ID : 3768639

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Efek Diuretik dan Daya Larut Batu Ginjal Dari Ekstrak Daun Mangkokan (Nothopanax scutellarium. Merr) Elisma Elisma; Fitri Maya Sari; Helmi Arifin
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Research on the effects of diuretics and solubility of kidney stones of Mangkokan leaf (Nothopanax scutellarium Merr.) extract has been done. Testing the solubility of kidney stones performed on 4 groups of test animals, namely the control group (without extract), The treatment dose groups of 0.5%, 1%, and 2%. Level of kidney stones are dissolved in the control group, 0.5%, 1% and 2% are 0.00521%, 0.01232%, 0.02433% and 0.05669% respectively. These result indicate a difference in dissolving kidney stones. Diuretic effect tested on 15 white male rats were divided into 5 groups of tests, one positive control group (furosemide), 1 negative control group (tween 80 1%), 3 treatment groups (doses of 125; 250 and 500 mg/kg BW). The result showed that all of three doses of extract have diuretic effect.

Pengaruh Pemberian Ekstrak Daun Gaharu (Aquilaria Malaccensis Lam.) Terhadap Aterosklerosis Pada Burung Puyuh Jantan (Coturnix-Coturnix Japonica) Suhatri Suhatri; Dian Zaini Putra; Elisma Elisma
Jurnal Farmasi Higea Vol 6, No 2 (2014)
Publisher : STIFARM Padang

Study about the influence of agarwood leave’s extract (Aquilaria malaccensis Lam.) on the formation of atherosclerosis in male quail (coturnic-coturnix japonica) induced high fat feeding and prophylthiourasil. Animal experiments were grouped into 5 consisting of Group I as a negative control only given food strander, group II as a positive control and PTU given MLT groups III, IV, V given leaf extract of aloes with a dose of 100 mg / kg BW, 300 mg / kg BW, 900 mg / kg BW and, along with the MLT and PTU the extract was given orally once a day for 60 day. The doses used were 100, 300, 900 mg/kg body weight respectively. Control groups was given food standar. Result showed that the administration of the agarwood leaf extract could prevent formation of atherosclerosis in male quail significantly (P < 0.05). The optimal effect showed doses 100 mg/kg BW.

Pengaruh Ekstrak Etanol Herba Pecut Kuda Stachytarpheta jamaicensis (l.) Vahl Terhadap Fungsi Hati Dan Kreatinin Urin Mencit Putih Jantan Elisma Elisma; Deni Kurniati; Helmi Arifin
Jurnal Farmasi Higea Vol 2, No 2 (2010)
Publisher : STIFARM Padang

Research on the effect of ethanol extract of pecut kuda (Stachytarpheta jamaicensis (L) Vahl) against liver and kidney function in male white mice have been done. Extracts administered orally with various doses of 150, 300 and 600 mg / kg bw once daily for 15, 30 and of 45 days. As a control group used white males mice who were given only 0.5% Na CMC. Activity SGPT and SGOT, creatinine clearance, renal function and the percentage ratio of organ weight were measured. The result showed that the extract at given doses effects liver function (p<0.05) and not effects the urinary creatinine levels (p> 0.05)

Efek Analgetik Ekstrak Etanol Daun Tapak Liman (Elephantopus scaber L.) Pada Mencit Putih Jantan Surya Dharma; Adirman Adirman; Elisma Elisma
Jurnal Farmasi Higea Vol 5, No 1 (2013)
Publisher : STIFARM Padang

Study about the analgesic effect of aethanolic extract of tapak liman leaf (Elephantopus scaber L) of white mice mice induced acetat acid 1% has been done. Extract was administered orally of variation dose 100, 300 and 900 mg/bw once daily until 7, 14 and 21 day. Results showed that giving of aethanolic extract of tapak liman leaf could decreased amount of stretching significantly.

Pengaruh Ekstrak Daun Binahong (Anredera Cordifolia (Tenore) Steen) Terhadap Volume Urin Dan Hambatan Pembentukan Batu Ginjal Pada Tikus Terinduksi Etilen Glikol Helmi Arifin; Vivi Resviana; Elisma Elisma
Jurnal Farmasi Higea Vol 6, No 2 (2014)
Publisher : STIFARM Padang

Research on the effect of binahong leaf extract (Anredera Cordifolia (Tenore) Steen) on urine volume and resistance kidney stone formation in rat induced by ethylene glycol has been done. It purposed to look up the ability of the binahong leaf extract to increase the urine volume and kidney stones shed on rats white males. That kidney stone formation induced by 0,75% ethylene glycol and 2% ammonium chloride for 7 days. 25 white male rats were divided into 5 groups, group I were given drinking water (negative control), group II in the induction for 7 days (positive control), group III, IV and V were induced dose groups and given the extract at a dose of 50 mg/kg BB, 150mg/kg BB and 450mg/kg BB. Extracts was given on day 8-28, 24-hour urine volume were collected on days 7, 14, 21 and 28 for calcium level was measured by atomic absorption spectrophotometer and oxalat levels with ultraviolet and visible spectrophotometer. Data were analyzed by two-way ANOVA followed by advenced Duncan test. The urine volume was not significantly influenced by treatment factors and the duration of administration (P>0.05), while the levels of calcium and oxalat significantly influenced by treatment factors and the long time of administration (P<0.05) based on these results it could be concluded that binahong leaf extract could increase the urine volume and kidney stones shed. The effective dose is the dose kidney stone shed 450mg/kgBB. So the higher the dose and the longer the time of administration of calcium and oxalate levels also increased in the urine volume of rat white males.

Efek Diuretik dan Daya Melarutkan Batu Ginjal Dari Ekstrak Herba Pecut Kuda (Stachytarpheta jamaicensis (L)Vahl) Helmi Arifin; Masitah Masitah; Elisma Elisma
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

The herbal extract of pecut kuda’s potencies on dissolving kidney stones and it’s diuretic effect has been studied. Test dissolve kidney stones performed in vitro by dissolving the crystals or stones are usually found in the kidney. Test were carried out at 4 treatment groups, control (no extract), 0.1%; 1% and and 2% groups. In the control group, the levels of dissolved kidney stones at 52.116 ppm, while the group of 0.5%, 1% and 2% at 56.140 ppm, 61.592 ppm and 76.602 ppm respectively. One-way ANOVA test result and test advanced non-parametric Kruskal-wallis test showed that of the three consentrations of the extract has a difference in dissolving kidney stones. Diuretic effect tested on 15 white male rats were divided into 5 groups, where in the extract is administered orally. The test group was divided into a positive group (furosemide), 1 negative group (given Na-CMC) and the 3 treatment groups (125; 250 and 500 mg/kg BW). Volume of rat urine into variable observations. Based on the results of two-way ANOVA test and test advanced non-parametric Friedman test show that all three doses of the test has diuretic effect. So that the conclutions of this study are horse whip herbal extracts can dissolve kidney stones and has a diuretic effect on test animals.

Pengaruh Ekstrak Etanol Daun Mangkokan (Nothopanax scutellarium. Merr) Terhadap Fungsi Hati Dan Kadar Kreatinin Urin Mencit Putih Jantan Helmi Arifin; Rahmi Yulia Nesia; Elisma Elisma
Jurnal Farmasi Higea Vol 3, No 2 (2011)
Publisher : STIFARM Padang

The effect of ethanolic extract of Nothopanax scutellarium. Merr on liver function and urine creatinine level of male white mices had been done. The extract was administered orally with variation of dose at 150, 300, 600 mg/kg BB one times a day for 15, 30, 45 days. As a control group was used male white mices that administered only Na CMC 0,5% solution. The result showed that administered of ethanolic extract Nothopanax scutellarium. Merr at variation of dose did not influence on liver function and urine creatinine level (p>0,05).

Pengaruh Pemberian Jus Buah Labu Kuning Cucurbita moschata (Duch.) Poir. Terhadap Tukak Lambung Tikus Putih Betina Yang Diinduksi Dengan Etanol Absolut Suhatri Suhatri; Relly Sapta Rahmat Hura; Elisma Elisma
Jurnal Farmasi Higea Vol 3, No 2 (2011)
Publisher : STIFARM Padang

The effect of the pumkin juice Cucurbita moschata (Duch.) Poir. on the ulcer of white female rat induced by absolut ethanol was investigated using oral method. With The reseveral doses 0.4 ; 0.8 ; and 1.6 ml/200 g body weight doses. The result showed that the juice with 0,4, 0,8, and 1,6 ml/200 g body weight dose were able to cure the ulcer with curative ratio for each rasio dose are 22.22 %, 52.89 % and 71.04 %. It’s shows that higher dose give better result. The juice can also significantly decrease the gastric pH of rat induced by ethanol absolut to it’s normal value (P<0,05).

Pengaruh Ekstrak Etanol Daun Sirsak (Annona Muricata L.) Terhadap Kadar LDL Pada Mencit Putih Jantan Surya Dharma; Oki Supanda; Elisma Elisma
Jurnal Farmasi Higea Vol 6, No 1 (2014)
Publisher : STIFARM Padang

Study about the influence of the aethanolic extract of Annona muricata L on male mice induced by high fat diet and propylthiouracil has been done. The aethanolic extract of Annona muricata L was given orally one a day for 7, 14, and 21 days. The doses used were 2, 6, 18 mg/20 g body weight respectively. Negative control group was given standard food. Parameters were measured blood levels of LDL. Result showed that the giving of the aethonalic extract of Annona muricata could decrease blood levels of LDL significantly (p> 0.05). Whereas the factors of the days does not show significantly (p> 0.05).

Pengaruh Ekstrak Daun Jati (Tectona grandis L.f) Terhadap Fungsi Hati Dan Fungsi Ginjal Pada Mencit Putih Jantan Elisma Elisma; Novi Priyoka Putra; Helmi Arifin
Jurnal Farmasi Higea Vol 3, No 2 (2011)
Publisher : STIFARM Padang

Study about sub acute toxicity of jati leaf extract toward white male mice has been done, which consist of SGPT activity for liver function test, creatinine clearance for kidney function test and organ’s weight ratio. The extract was administered orally once a day for 15, 30 and 45 days with variable dose of 150, 300 and 600 mg per kg body weight. The result showed that there were no significant effect of jati leaf extract administration to the SGPT activity, kidney function and organ’s weight ratio (p > 0.05).

Co-Authors Adirman Adirman Benny Benny Deni Kurniati Dian Zaini Putra Ella Handalia Fitri Maya Sari Helmi Arifin Hendri Fatriona Hermansyah Hermansyah Masitah Masitah Muhammad Syafrudin Novi Priyoka Putra Oki Supanda Rahmi Yulia Nesia Relly Sapta Rahmat Hura Suhatri Suhatri Surya Dharma Vivi Resviana Yufri Aldi

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