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All Journal Jurnal Sains dan Teknologi Farmasi JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Farmasi Higea
Fithriani Armin
Fakultas Farmasi Universitas Andalas
Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Jurnal Sains dan Teknologi Farmasi

 1 
PENGGUNAAN METODE RASIO ABSORBAN DALAM PENETAPAN KADAR PARASETAMOL DAN SALISILAMIDA BERBENTUK SEDIAAN CAMPURAN Armin, Fithriani; Dantes, Ehrlich Von
Jurnal Sains dan Teknologi Farmasi Vol 17, No 2 (2012)
Publisher : Universitas Andalas

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Abstract

A study on the determination of paracetamol and salicylamide in a mixture by absorbance ratio method has been done. The absorption spectrum of both compounds crossing one each other at isoabsorption point. The maximum wavelength of paracetamol, salicylamide, and wavelength of isoabsorpsi line which show the relation of paracetamol fractions in a mixture containing paracetamol and salicylamide in various proportions and absorbances at isoabsorption wavelength was constructed. The measurement of absorbance was done at 247,2 nm and 300,3 nm. The experiment showed that the absorbancy ratio method can be used to determine paracetamol and salicilamyde. The percent recovery of paracetamol was 101,31 % with 0,642 % of standard deviation and coefficient of variation 0,616 %. The salicylamide content was then calculated and found to be 99,66 % with 0,863 % of standard deviation and 0,861 % of coefficient variation.
Penggunaan Metode Rasio Absorban dalam Penetapan Kadar Parasetamol dan Salisilamida Berbentuk Sediaan Campuran Dantes, Ehrlich Von; Armin, Fithriani; Rusdi, Rusdi
Jurnal Sains dan Teknologi Farmasi Vol 17 No 2 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

A study on the determination of paracetamol and salicylamide in a mixture by absorbance ratio method has been done. The absorption spectrum of both compounds crossing one each other at isoabsorption point. The maximum wavelength of paracetamol, salicylamide, and wavelength of isoabsorpsi line which show the relation of paracetamol fractions in a mixture containing paracetamol and salicylamide in various proportions and absorbances at isoabsorption wavelength was constructed. The measurement of absorbance was done at 247,2 nm and 300,3 nm. The experiment showed that the absorbancy ratio method can be used to determine paracetamol and salicilamyde. The percent recovery of paracetamol was 101,31 % with 0,642 % of standard deviation and coefficient of variation 0,616 %. The salicylamide content was then calculated and found to be 99,66 % with 0,863 % of standard deviation and 0,861 % of coefficient variation.
Identifikasi dan Penetapan Kadar Merkuri (Hg) dalam Krim Pemutih Kosmetika Herbal Menggunakan Spektrofotometri Serapan Atom (SSA) Armin, Fithriani; Zulharmita, Zulharmita; Firda, Dinda Rama
Jurnal Sains dan Teknologi Farmasi Vol 18 No 1 (2013)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

Telah dilakukan penelitian analisis kandungan merkuri dalam 3 sampel krim pemutih kosmetika herbal. Sampel diekstraksi dengan cara digesti basah selama 3 jam pada suhu ±95°C sampai diperoleh larutan bening. Selanjutnya merkuri ditentukan secara kualitatif dan kuantitatif dengan pereaksi warna dan menggunakan metoda spektrofotometri serapan atom. Hasil analisis kualitatif menunjukkan bahwa semua sampel mengandung merkuri. Kadar merkuri pada sampel 1, 2, 3 berturut-turut adalah sebesar 0,56%; 0,28% dan 0,45 %. Kadar Hg pada sampel tersebut melanggar Peraturan Menkes RI No.376/MenKes/Per/VIII/1990 dan PerMenKes RI No.445/MenKes/Per/V/1998 yang isinya melarang penggunaan merkuri dalam sediaan kosmetika.
Co-Authors Adek Zamrud Adnan Bita Revira Dinda Rama Firda Ehrlich Von Dantes Ermadanis Ermadanis Mahyuddin Mahyuddin Roslinda Rasyid Rusdi Rusdi Sri Indah Kesuma Yuli Yani Dewi Zulharmita Zulharmita Zulharmita Zulharmita