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All Journal Jurnal Farmasi Higea
Helvia Angraeni
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Medicine & Pharmacology

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Kompleks Inklusi Amlodipin Besilat – β-siklodekstrin Dengan Metode Kneading Indra Makmur; Auzal Halim; Maria Dona Oktavia; Helvia Angraeni
Jurnal Farmasi Higea Vol 10, No 1 (2018)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (710.726 KB) | DOI: 10.52689/higea.v10i1.194

Abstract

Preparation and characterization of inclusion complex of amlodipine besylat with β - cyclodextrin has been done. Preparation of the inclusion complex was carried kneading method. Formed inclusion complex was characterized by X-ray diffraction, FT - IR spectrophotometer, Scanning Electron Microscopy (SEM), and the dissolution test. Data from X-ray diffraction, FT - IR, SEM can be concluded that inclusion complexes with kneading method give the best results. The dissolution efficient  results showed that the inclusion complex of amlodipine besylat - β - cyclodextrin with a kneading method increased significantly when compared with the active ingredient and the mixture of physics.
Co-Authors Auzal Halim Indra Makmur Maria Dona Oktavia