Bambang Setyohadi
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Journal : Jurnal Penyakit Dalam Indonesia

Bone Mass Density in HIV/AIDS Patients Mulansari, Nadia Ayu; Sukmana, Nanang; Setyohadi, Bambang; Setiati, Siti
Jurnal Penyakit Dalam Indonesia Vol. 3, No. 4
Publisher : UI Scholars Hub

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Association between Disease Activity and Depression inRheumatoid Arthritis Patients Mudjaddid, E; Puspitasari, Myra; Setyohadi, Bambang
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 4
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Introduction. Rheumatoid Arthritis (RA) is a chronic, systemic disease that cause synovialinflammation and progressive destruction to cartilages and deformities. Prevalence of depressionin RA patients is 20 to 30%. Disease activity is considered to have association with depression. This study aims to identify the prevalence of depression in RA patients and the associationbetween disease activity index and depression in RA patients. Methods. A cross-sectional study of 145 RA patients that fulfilled the inclusion criteria was conducted in Rheumatology Outpatient Clinic at Cipto Mangunkusumo Hospital Jakarta from January to March 2017.Evaluation of Disease Activity Score - 28 (DAS 28) and Back Depression Inventory (BDI) was done to the patients. Statistical analysis was performed using SPSS version 20. Categorical variables were compared using chi-square test. Results. A total of 145 subjects were included in this study and most of them were female (90.3%). Median age of subjects was 55 years (range 19-83 years). Forty five subject (31%) were identified having psychosocial stressor. The proportion of depression in RA patients was 35.9% (95% CI 30-42%). Based on Disease Severity Score, it was found that subject with mild, moderate, and severe score were 24 (82.8%), 52 (66.7%), and 4 (23.5%), respectively. There was significant association between disease activity with depressionin rheumatoid arthritis patient (p= 0.001).
Reliability and Validity Test Of Indonesian Version Short Form12 Quality of Life Questionnaire in Rheumatoid Arthritis Patient Falah, Nabil Mubtadi; Putranto, Rudi; Setyohadi, Bambang
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 3
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Introduction. Rheumatoid Arthritis is a chronic disease requiring a long-term medication affecting quality of life. Short Form 12 is a generic questionnaire to assess patients quality of life and has been validated in England. This study was designed to test reliability and validity of Indonesian version of SF-12 questionnaire. Methods. Sixty-five patients with clinically diagnosed RA using ACR/EULAR criterion were interviewed using Short Form 36 and Short Form 12 questionnaire. Validity was assessed with construct validity and external validity, while reliability tested with internal consistency and test-retest method. Results. Short-Form 12 (Indonesian Version) did not proved having a good validity, as it have a poor correlation between RE and MH domain in SF-36 and SF-12. Indonesian version of SF-12 shown a poor internal consistency (Cronbach Alpha: 0.561- 0.754) but a good test and retest reliability ( intraclass correlation coefficient: 0.844-0.980, p <0,05) Conclusions. Indonesian version SF-12 is not reliable nor valid to evaluate quality of life in RA patients.
Predictors of Health-Related Quality of Life in Adult HemophiliaPatients in Cipto Mangunkusumo Hospital Prasetyawaty, Findy; Sukrisman, Lugyanti; Setyohadi, Bambang
Jurnal Penyakit Dalam Indonesia Vol. 3, No. 3
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Introduction. Currently, one of the main focus of hemophilia treatment is to increase health-related quality of life. Due to financial constraints, factor VIII substitution is used only on demand in Indonesia, which might contribute to musculoskeletal complications and affect the quality of life of adult hemophilia patients. This study aimed to evaluate quality of life of adult hemophilic patients and its related factors. Methods. A cross-sectional study on hemophilia patients aged 18 years or older was conducted at the Hematology-Medical Oncology outpatient clinic, Cipto Mangunkusumo Hospital Jakarta from March to May 2012. The radiologic assessment for arthropathy used the Arnold-Hilgartner score and health-related quality of life was assessed by the SF-36 questionnaire, using norm-based scoring system with normal value of 45 (individual) and 47 (group scale score). Subjects were categorized based on the level of factor VIII or IX and clinical severity (the number of bleeding episodes during the last 12 months). Results. In 66 subjects aged 18-57 (median 28) years old, the scores of the SF-36 ranged from 42.1 (role physical) to 60.9 (vitality). The physical and mental component summary scored 40.0 and 57.7. Clinical severity (p=0.001) and the severity of arthropathy (p=0.034) significantly influenced the SF-36 scores. The multivariate analysis showed that clinical severity significantly influenced the SF-36 scores (p=0.004; AUC 73%). The combination of clinical severity and severity of arthropaty increased the AUC to 76.6%. Conclusions. Health-related quality of life in adult hemophilia showed poor results in physical components. The clinical severity and arthropathy were predictors of health-related quality of life in adult hemophilic patients. The combination of clinical severity and arthropathy had better value in predicting health-related quality of life in adult hemophilia.