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All Journal Journal of Dedicators Community Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Farmasi Indonesia
Jamilah Sarimanah
Universitas Setia Budi
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Dagusibu, P3K (Pertolongan Pertama Pada Kecelakaan) di Rumah dan Penggunaan Antibiotik yang Rasional di Kelurahan Nusukan Ika Purwidyaningrum; Jason Merari Peranginangin; Mardiyono Mardiyono; Jamilah Sarimanah
Journal of Dedicators Community Vol 3, No 1 (2019)
Publisher : Universitas Islam Nahdlatul Ulama Jepara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.582 KB) | DOI: 10.34001/jdc.v3i1.782

Abstract

The purpose of the service activity is to provide information and education to the public about dagusibu, P3K at home and rational use of antibiotics. Health counseling is needed by the community because it is known that the community. The GKSO Movement (Conscious Family Movement) is a program launched by the Indonesian Pharmacists Association (IAI) which is an effort to improve public understanding of medicines through dissemination of medicines, Dagusibu (Get, Use, Save and Dispose) medical equipment, medicine first aid treatment, and knowledge of antibiotics. The service partner, a resident of RT 08 RW 14, lacks awareness in maintaining cleanliness and still does not know the symptoms caused by an illness. The results of dedication show that citizens gain new knowledge and understand the material provided as a purpose of service
Hypoglycemic effect test of Ethanolic extract of Baligo seeds (Benincasa Hispida (Thumb.) Cogn.) on white male rats wistar strain with Alloxan induction Dina Maryati; Jamilah Sarimanah; Wiwin Herdwiani; lrfan Zamzani
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 11 No. 2 (2019): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3965.822 KB) | DOI: 10.35617/jfionline.v11i2.4

Abstract

Baligo merupakan tanaman asli dari daerah tropis yang di Indonesia dikenal dengan sebutan kundur atau labu besar. Baligo antara lain mengandung karbohidrat, glikosida, alkaloid, fitosterol, gum dan mucilago, saponin, protein dan asam amino bebas, serta flavonoid. Kandungan kimia pada biji baligo yang diduga memiliki aktivitas antidiabetes adalah flavonoid dan  saponin.  Penelitian  ini  bertujuan untuk mengetahui efek hipoglikemik ekstrak etanol biji baligo (Benincasa hispida (Thumb.) Cogn.) dan mengetahui apakah semakin besar dosis ekstrak etanol biji baligo (Benincasa hispida (Thumb.) Cogn.) semakin besar efek hipoglikemik pada tikus putih jantan galur wistar dengan induksi aloksan. Penelitian ini menggunakan metode induksi aloksan dimana tikus dibagi menjadi lima kelompok perlakuan yaitu masing- masing kelompok terdiri dari lima ekor tikus. KI sebagai kontrol negatif (CMC 0,5%), K II sebagai kontrol positif (glibenklamid) dengan dosis 0,09 mg/200 g BB tikus, dan K III, IV, V diberikan dosis ekstrak etanol biji baligo berturut-turut 4,10 mg/200 g BB tikus, 8,21 mg/200 g BB tikus, 16,42 mg/200 g BB tikus. Semua kelompok diinduksi aloksan pada hari ke-0 (setelah dipuasakan 16 jam) secara intraperitoneal. Pemeriksaan kadar gula darah dilakukan pada hari ke-4 dan ke-8 setelah pemberian sediaan uji. Hasil analisa statistik menunjukkan bahwa semakin besar dosis ekstrak etanol biji baligo (4,10 mg/200 g BB tikus, 8,21 mg/200 g BB tikus, 16,42 mg/200 g BB tikus) tidak semakin besar efek hipoglikemik pada tikus putih jantan galur wistar dengan induksi aloksan.
ANALISIS BAHAN KIMIA OBAT ASAM MEFENAMAT DALAM JAMU PEREDA NYERI YANG BEREDAR DI NGAWI DAN ONLINE SHOP SECARA KLT DAN SPEKTROFOTOMETRI UV-VIS Reslely Harjanti; Intan Pratiwi; Jamilah Sarimanah
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p7-16

Abstract

One of the medicinal chemicals (BKO) that is abused in herbs preparations for pain reliever is mefenamic acid. Mefenamic acid is a class of non-steroidal anti-inflammatory drug (NSAID). The addition of mefenamic acid in herbs medicine aims to increase the effect of pain relief, but can caused harmful effects, including digestive tract disorders, hemolytic anemia, and seizures. The purpose of this study is to determine the presence of mefenamic acid in pain reliever herbs circulating in Ngawi and online shop.The samples in this study were several brands of pain reliever herbs from 4 herbal medicine shops (A,B,C, and D). This research is using purposive sampling method based on inclusion criteria. Samples was analyzed qualitatively by thin layer chromatography (TLC) method using cyclohexane:chloroform: methanol:glacial acetic acid (60:30:5:5) as mobile phase and silica GF254 as stationary phase. Quantitive analysis using spectrophotometry UV-Vis method. The results showed that 10 of 16 samples of herbal pain reliever were positive for mefenamic acid with levels ranging from 1.28% -7.30%. The UV-Vis spectrophotometric analysis method suitable for the analysis of mefenamic acid in herbal medicine for pain reliever based on validation results that meet the requirements includes linearity with r value 0.99956, accuracy 8 ppm was 100.32%, 10 ppm was 100.84%, 12 ppm was 100.61%, precision 1.33%, LOD 0.8914299023 ppm, and LOQ 2.701302734 ppm.
Co-Authors Dina Maryati Intan Pratiwi Jason Merari Peranginangin lrfan Zamzani MARDIYONO MARDIYONO PURWIDYANINGRUM, IKA Reslely Harjanti Wiwin Herdwiani