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Avidlyandi Avidlyandi
Universitas Bengkulu
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Journal : BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains

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Aktivitas Antibakteri Ekstrak Etanol Daun Tapak Kuda (Ipomoea pes-caprae (L.) R. Br.) terhadap Bakteri Staphylococcus epidermidis Sri Wahyu Kurnia Putri; Devi Nurhasana; Avidlyandi Avidlyandi; Irfan Gustian; Sipriyadi Sipriyadi; Morina Adfa
BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Vol 4 No 2 (2021): BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.754 KB) | DOI: 10.31539/bioedusains.v4i2.2864

Abstract

This study aimed to determine the antibacterial activity of the ethanol extract of the leaves of Tapak Kuda (Ipomoea pes-caprae) against Staphylococcus epidermidis. The method used was Kirby-Bauer for the antibacterial test with various concentrations of ethanolic extract of I. pes-caprae leaf extract: 5 mg/mL, 20 mg/mL, 35 mg/mL, and 50 mg/mL, with five replications. The antibiotic clindamycin was used as a positive control, while DMSO was a negative control. The results showed that after 24 hours of incubation, the zone of inhibition of bacterial growth was demonstrated by the experimental and the positive control groups, while the negative control did not show the zone of inhibition. The diameter of the largest inhibition zone (11.40 mm) was at a 50 mg/mL test concentration, which was indicated as a strong category. In conclusion, the ethanolic extract of the leaves of I. pes-caprae can inhibit the growth of S. epidermidis at all test concentrations. Keywords: Antibacterial, Ipomoea pes-caprae, Staphylococcus epidermidis
Kombinasi Ekstrak Metanol Daun Ketepeng Cina (Cassia alata Linn.) dengan Enam Ekstrak Tumbuhan Terpilih dalam Menghambat Pertumbuhan Bakteri Staphylococcus aureus Lisna Hamni; Avidlyandi Avidlyandi; Charles Banon; Khafit Wiradimafan; Deni Agus Triawan; Risky Hadi Wibowo; Morina Adfa
BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains Vol 5 No 2 (2022): BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/bioedusains.v5i2.3996

Abstract

This study aimed to determine the antibacterial activity and the effect of the combination of methanol extract of the leaves of Chinese ketepeng (Cassia alata Linn.) with six selected plant extracts against Staphylococcus aureus bacteria. The method used is well diffusion and paper tape method. The concentration of the test extract was 100 mg/mL (1:1), DMSO 50% v/v was used as a negative control and the antibiotic clindamycin as a positive control. The results showed that most of the combinations of the methanol extract of the Chinese ketepeng leaf (C. alata) with the six selected plant extracts produced an average diameter of the inhibition zone, which was greater than the average diameter of the inhibition zone of every single extract. However, the average diameter of the combined inhibition zones was not more significant than the sum of the average diameters of the inhibition zones of every single extract. In conclusion, the combination of the methanol extract of the Chinese ketepeng leaf (C. alata) with six selected plant extracts had additive/indifferent effects in inhibiting the growth of S. aureus. Keywords: Antibacterial, Cassia alata Linn, Combination, Staphylococcus aureus
Co-Authors Charles Banon Devi Nurhasana Irfan Gustian Khafit Wiradimafan Lisna Hamni Morina Adfa Risky Hadi Wibowo Sipriyadi Sri Wahyu Kurnia Putri Triawan, Deni Agus