Article Per Year (5 Year)
p-Index From 2019 - 2024
0.751
P-Index
This Author published in this journals
All Journal Jurnal Farmagazine Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Jurnal Mahasiswa Ilmu Kesehatan Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Gina Septiani Agustien
Universitas Perjuangan Tasikmalaya
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
UJI AKTIVITAS TONIKUM INFUSA BUAH KAPOLAGA (Amomum cardamomum) PADA MENCIT (Mus musculus) Gina Septiani Agustien; Susanti Susanti
Jurnal Farmagazine Vol 7, No 1 (2020): Jurnal Farmagazine
Publisher : STF Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47653/farm.v7i1.152

Abstract

Kebutuhan suplemen penambah stamina atau tonikum bisa didapatkan dari mengkonsumsi tanaman herbal. Pemanfaatan tanaman herbal untuk tonikum mempunyai kelebihan tersendiri dibandingkan senyawa sintetik. Buah kapolaga (Amomum cardamomum) adalah tanaman perdu banyak terdapat di wilayah Indonesia, masyarakat biasanya menggunakan kapolaga untuk bumbu masakan. Buah kapolaga memiliki potensi besar dalam bidang farmasi, yaitu adanya senyawa flavonoid yang bermanfaat sebagai tonikum. Tujuan penelitian adalah untuk mengetahui mengetahui efek tonikum pada mencit dan menentukan pada konsentrasi berapa dapat memberikan efek tonikum yang optimum. Uji efek tonikum dilakukan menggunakan uji renang kemudian dilihat waktu pada petahanan berenang mencit. Metode uji renang yang digunakan adalah natatory exhaustion. Hasil penelitian ini menunjukkan bahwa infusa buah kapolaga pada dosis 2,5 g/kgBB, 5,0 g/kgBB dan 10 g/kgBB pada metode ketahanan berenang menunjukkan efek tonikum pada mencit (Mus musculus). Infusa buah kapolaga pada konsentrasi 10 g/kgBB menunjukkan efek tonikum yang paling baik pada mencit, tetapi efeknya masih lebih kecil daripada pemberian kafein sebagai pembanding. Kata Kunci: Buah Kapolaga, Infusa, Mencit, Tonikum
Formulasi Dan Uji Stabilitas Fisik Sediaan Masker Gel Peel-Off Ekstrak Etanol Umbi Porang (Amorphophallus Muelleri) Sebagai Antioksidan Wahyu Firmansyah; Gina Septiani Agustien; Nitya Nurul Fadilah
Jurnal Anestesi Vol. 1 No. 4 (2023): Oktober : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v1i4.510

Abstract

A peel-off gel mask is a cosmetic used for facial skin care in the form of a gel. Porang tuber extract peel-off gel mask (Amorphophallus muelleri) contains polyphenolic tannins which are efficacious as antioxidants. This study aims to determine the formulation of peel-off gel mask preparations of porang tuber extract and to determine the physical evaluation and antioxidant test of peel-off gel mask preparations of porang tuber extract using the DPPH method. Experimental formulation method with 7% polyvinyl alcohol (PVA) base. The active ingredient used is porang tuber extract with a concentration of 0.5% (F1), 1% (F2), and 1.5% (F3). Evaluation of the preparations carried out were organoleptic test, homogeneity test, pH test, drying preparation test, spreadability test, hedonic test and stability test. Based on the results of the stability test, it was shown that the peel-off gel mask preparation of porang tuber ethanol extract at various concentrations met the requirements for each test parameter. The antioxidant test results showed that F1 had an IC50 value of 48.75 ppm, F2 had an IC50 value of 43.18 ppm, and F3 had an IC50 value of 11.15 ppm which means that the three formulas have very strong antioxidant activity.
Formulasi Dan Evaluasi Sediaan Fisik Krim Antioskidan Ekstrak Pelepah Pohon Aren (Arenga Pinnata Merr.) Iqbal Abdul Raup; Gina Septiani Agustien; Nitya Nurul Fadilah
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 1 No. 4 (2023): Oktober : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Politeknik Pratama Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v1i4.2447

Abstract

Aren (Arenga pinnata Merr.) is a biological resource that is thought to have antioxidant abilities and is easily found in all regions of Indonesia. The stem is used for traditional medicine to relieve itching and scars on the skin. The aim of this study was to find out whether palm frond extract (Arenga pinnata Merr.) can be formulated into a cream and has good quality. The research method used is experimental in nature by formulating the extract into three formulations namely extract concentrations of 1%, 2%, 3%. Data analysis was carried out using qualitative analysis including organoleptic tests, homogeneity tests, and quantitative analysis including pH tests, spreadability tests, adhesion tests, viscosity and using One Away ANOVA statistics. The results of the analysis showed that there was no significant difference in the concentration of palm frond cream on pH with a sig. value of 0.279 (sig. > 0.05), adhesion of 0.544 (sig. > 0.05) and viscosity that met the standard of good cream viscosity, namely between (2000 - 50000 cps). Analysis of the research data shows that the three variations of the extract can be formulated in cream preparations and have standard quality cream preparations that meet the requirements, there is no effect of variations in the concentration of palm fronds extract. The test results of the antioxidant activity of palm tree fronds that have been carried out show that in Formulas I, II, and III the IC50 values ​​were 8.88 µg/mL, 9.89 µg/mL, 6.83 µg/mL and vitamin C had a IC50 of 0.726 µg/mL. The best antioxidant content was found in formulation III with an IC50 value of 6.83 µg/mL.
Formulasi Dan Uji Aktivitas Antioksidan Sediaan Facemist Ekstrak Umbi Wortel (Daucus Carota L) Alin Marlina; Gina Septiani Agustien; Susanti Susanti
Jurnal Mahasiswa Ilmu Kesehatan Vol. 1 No. 4 (2023): Oktober: Jurnal Mahasiswa Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v1i4.255

Abstract

Excessive exposure to sunlight is a source of free radicals that cause damage to the skin such as redness, dullness, and aging, so skincare containing antioxidants is needed, one of which is a face mist made from carrot root extract. The carrot (Daucus carota L) is a plant rich in antioxidants such as β-carotene and vitamin C which can counteract free radicals. This research aims to determine whether carrot tuber extract can be formulated in a face mist preparation and to determine the value of antioxidant activity in the carrot tuber extract face mist preparation. The method used in this study is the experimental method. Preparation of carrot root extract was carried out using the maceration method with 70% ethanol solvent. Facemist carrot root extracts was made with various concentrations of FI 1%, FII 3%, and FIII 5%. All preparations were subjected to physical stability (organoleptic, pH, spray spreadability, dry time, and homogeneity) and antioxidant activity tests using the DPPH method. The results of physical stability stated that all formulas met the physical quality requirements. The antioxidant activity value of carrot tuber extracts facemist at concentrations of 1%, 3%, and 5% has an IC₅₀ value of 41.31ppm, 34.64ppm, and 28.80ppm respectively. This value is in the very strong category. The conclusion of this study is that carrot root extract can be formulated as a face mist preparation and has a very strong antioxidant value.
Co-Authors Alin Marlina Iqbal Abdul Raup Nitya Nurul Fadilah Susanti Susanti Wahyu Firmansyah