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All Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan
Ninuk Dwi Ariningtyas
Universitas Muhammadiyah Surabaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Comparison of Platelet Levels between Preeclampsia and Eclampsia Patients at Wiyung Sejahtera Hospital, Surabaya Reyke Fortuna Maudy Sintya; Ninuk Dwi Ariningtyas; Annisa Nurida; Nabil Salim Ambar
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 8, No 1 (2021): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (81.635 KB) | DOI: 10.26714/magnamed.8.1.2021.10-17

Abstract

Background: Indonesia is a developing country with a high maternal mortality rate (MMR) and perinatal mortality, the third highest in ASEAN and the second highest in the South East Asian Nation Regional Organization. In pregnancy hypertension has been proven that oxidants, especially if increased fat peroxide will damage endothelial cells called endothelial dysfunction. Vasospasm that occurs also induces platelet integration and endothelial damage which adds to the contribution in maintaining platelet dysfunction and triggering the use of platelets. Thrombocytopenia is the most important sign of the severity of preeclampsia.Objective: to determine the comparison of platelet levels in patients with preeclampsia with eclampsia.Methode: This study was observational cross sectional method. The sample in this study was a total sampling, using purposive sampling of patients with preeclampsia and eclampsia at the Wiyung Sejahtera Hospital in January-December 2019. The instrument used was using secondary data of medical records of patients.Results: Patients with preeclampsia have a minimum platelet level of 301,000/mm3, a maximum of 415,000/mm3, and an average of 351,733.33/mm3 with a standard deviation of 33,552.66/mm3. Patients with eclampsia have a minimum platelet level of 122,000/mm3, a maximum of 281,000/mm3, and an average of 209,200/mm3 with a standard deviation of 42,465.45/mm3. There are significant differences in platelet levels of patients with preeclampsia with eclampsia(p <0.05)..Conclusion: there is a significant difference between the platelet levels of patients with preeclampsia and eclampsia.
Relationship between Pregnant Woman Obesity Grade-1 and Grade-2 with The Incidence of Preeklampsia Ananda Frifiyant Mochammad Ilham; Ninuk Dwi Ariningtyas; Nur Mujaddidah Mochtar; Uning Marlina
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 9, No 2 (2022): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.9.2.2022.89-95

Abstract

Background: Preeclampsia is a hypertensive disorder that can increase maternal and fetal morbidity and mortality during pregnancy. Pregnant women with obesity are at higher risk of preeclampsia.Objective: To prove the relationship between pregnant women with grade-1 and grade-2 obesity and the incidence of preeclampsiaMethod: This study used the design of a prospective cohort. The population was pregnant women with obesity who got check-ups in Pregnancy Unit at Wiyung Sejahtera Hospital in Surabaya. This study used a consecutive sampling technique. The samples were pregnant women with BMI ≥ 25 with 34-38 weeks gestational age who signed the consent form. The data were analyzed through the Chi-Square test.Result: The results show that respondents who do not experience preeclampsia are dominated by pregnant women with grade-1 obesity by 70% and grade-2 obesity by 30%. Meanwhile, those who experience preeclampsia are dominated by pregnant women with grade-2 obesity by 75% and grade-1 obesity by only 25%. The results of the Chi-Square test analysis obtain a p-value of 0.007 with an odds ratio of 7,000.Conclusion: Pregnant women classified as grade-2 obesity have a seven times greater risk of experiencing preeclampsia compared to pregnant women with grade-1 obesity.
Co-Authors Ananda Frifiyant Mochammad Ilham Annisa Nurida Nabil Salim Ambar Nur Mujaddidah Mochtar Reyke Fortuna Maudy Sintya Uning Marlina