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Evaluasi Sediaan Krim dan Uji Toksisitas Akut Ekstrak Daun Nipah (Nypa fruticans Wurmb) Daerah Cilacap Dengan Fase Minyak VCO Sebagai Kandidat Antibakteri Tri Fitri Yana Utami
Indonesian Journal of Pharmacy and Natural Product Vol. 5 No. 1 (2022)
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (554.922 KB) | DOI: 10.35473/ijpnp.v5i1.1596

Abstract

Daun nipah dan VCO dapat digunakan sebagai antibakteri alami. Pada penelitian ini dilakukan pengembangan formulasi berupa sediaan krim ekstrak etanol daun nipah dengan fase minyak VCO untuk meningkatkan potensi dari kedua bahan alam tersebut. Tujuan penelitian ini adalah untuk mengetahui adanya kandungan senyawa flavonoid, tanin, saponin, steroid/triterpenoid pada ekstrak etanol daun nipah, mengetahui sifat fisik sediaan yang meliputi uji organoleptis, homogenitas, pH, viskositas, daya sebar, daya lekat dan uji toksisitas akut pada ekstrak. Proses ekstraksi daun nipah dilakukan menggunakan metode maserasi dengan pelarut etanol 96% diperoleh rendemen sebanyak 18,1%. Hasil uji fitokimia menujukan bahwa ekstrak etanol daun nipah positif mengandung flavonoid, tanin, saponin dan steroid/triterpenoid. Dihasilkan sifat fisik sediaan yang baik diperoleh pada formula 2, formula 3 dan formula 4. Dan Nilai LC50 ekstrak daun nipah yang diperoleh adalah 1140 ppm yang artinya ekstrak daun nipah tidak memiliki efek toksik.Kata kunci : Daun Nipah, Krim, VCO, Toksisitas
Hubungan Self Management Dengan Tingkat Kepatuhan Pasien Terhadap Keberhasilan Terapi Hipertensi Di Puskesmas Bonorowo Kebumen Untung Sridadi; Mika Tri Kumala Swandari; Tri Fitri Yana Utami
Pharmaqueous : Jurnal Ilmiah Kefarmasian Vol. 5 No. 1 (2023): Volume 5. Nomor 1, Mei 2023
Publisher : Prodi S1 Farmasi, Universitas Al Irsyad Al Islamiyyah Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v5i1.548

Abstract

Hypertension is a condition when blood pressure systolic over 140mmHg and diastolic blood pressure over 90mmHg . one _ effort for resolve hypertension is with self management or management self with obedience patient to success therapy hypertension . Study this aim for identify characteristics and connection patient and level percentage self management and level obedience patient to success therapy hypertension . Type study this is non - experimental nature correlational with approach cross sectional with use period on month December 2022. Method taking sample on study this that is purposive sampling . Data analysis was performed that is analysis bivariate and test chi square using the Statistical Package for the Social Science (SPSS) program. Study this carried out at the Health Center Bonorowo Kebumen . Population in study this that is all patient hypertension pure nor with participant who did examination at the Health Center as many as 106 respondents on period month December 2022. Based on results study self management sufferer hypertension as much as 49.0% of respondents is at on category enough . A total of 47.2 % of respondents own level obedience medium . There is connection significant Among self management with level compliance ( p-value 0.000) which is correlated (r-0.906) with direction connection positive . Conclusion there is connection significant Among self management with level obedience patient to success therapy hypertension at the health center Bonorowo Kebumen .
Pengaruh Edukasi Metode Cbia Terhadap Pengetahuan Swamedikasi Berdasarkan Konsep Dagusibu Di Kelompok PKK Desa Sawangan Kecamatan Kuwarasan Kabupaten Kebumen Ervina Laely Nuswantari; Tatang Tajudin; Tri Fitri Yana Utami
Pharmaqueous : Jurnal Ilmiah Kefarmasian Vol. 5 No. 1 (2023): Volume 5. Nomor 1, Mei 2023
Publisher : Prodi S1 Farmasi, Universitas Al Irsyad Al Islamiyyah Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v5i1.562

Abstract

Based on Badan Pusat Statistik (2022), more than 70% of sick people in Indonesia doing self-medicate (swamedikasi) when they have mild symptoms of illness without consulting a doctor. Self-medication is widely carried out by various group of people, one of which is housewives in PKK group Desa Sawangan, Kecamatan Kuwarasan, Kabupaten Kebumen. “Mothers” are determining part of health in the household, including in making drug selection decisions, so it needs to be accompanied by adequate knowledge about the proper implementation of selfmedication. CBIA (Cara Belajar Insan Aktif) program can be a solution to existing problems. CBIA is one of the community empowerement activities used in educating people to choose and use the right drugs in self-medication. This study aims to find out an overview of self-medicated knowledge and find out the influence of the application of the CBIA method to increase knowledge about drug self-medication based on the DAGUSIBU concept (Dapatkan, Gunakan, Simpan, Buang). This research method is a quantitative method of experimental type, one-grup pretest-posttest. Amount of sample in this research are 67 people was selected using the Purposive Sampling Method with inclusion dan exclusion criteria set by the researcher. The data analysis used was a paired t-test statistical test and obtained a signification value (2-tailed) of 0,001 <0,05 which showed a significant difference between the pretest dan post-test values. The CBIA program is effective in increasing knowledge of the PKK Community in Desa Sawangan, Kecamatan Kuwarasan, Kabupaten Kebumen.