Veli Sungono
Department Of Public Health, Faculty Of Medicine, Pelita Harapan University, Tangerang, Indonesia

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Cortisol dynamics and endothelin-1/nitric oxide ratio are associated with clinical vasospasme July, Julius; Yunus, Yesaya; Sungono, Veli; As’ad, Suryani; Suhadi, Budhianto; Islam, Andi A.
Medical Journal of Indonesia Vol 22, No 3 (2013): August
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (520.232 KB) | DOI: 10.13181/mji.v22i3.585

Abstract

Background: Cortisol dynamics in serum might be related to clinical vasospasm, also known as delayed ischemic neurological deficits (DIND). Two vasoactive substances that play a role in pathophysiology of DIND are endothelin-1 (ET1) and nitric oxide (NO), both are proved associated with cortisol. This study aimed to know how cortisol play a role on ET1/NO ratio and its relationship to DIND.Methods: This was a prospective cohort study for the first 14 days after aneurysmal subarachnoid hemorrhage (SAH). Patients with inclusion criteria will be enrolled for blood test before surgery, and post-operative day 2, 4, 7, and 10 (between 8:00-9:00 AM). The blood tests were performed for cortisol, ACTH, CBG, NO, and ET1. Free cortisol is calculated with Coolens equation. Logistic regression was used to see the interaction model and its scale. Bivariate analysis (corelation) was used to see the relationship between total cortisol, free cortisol, NO, ET1, and clinical vasospasm (DIND).Results: Forty-four patients are enrolled into this study (20 male; 24 females). Mean age is 52.02 years (52.02 ± 11.23). There were 29 patients (66%) within  DIND group and 15 patients Non-DIND as the control group. The mean of cortisol level shown is significantly higher in DIND group (35.99 ± 14.24) µg/dL compared to Non-DIND group (19.57 ± 6.19) µg/dL, p < 0.001. The mean of free cortisol level was significantly higher in DIND group (2.06 ± 1.094) µg/dL compared to non-DIND group (0.838 ± 0.365 µg/dL; p < 0.001). The Scatter Plot graph show that correlation of cortisol with ET1/NO ratio started increasing on day 4 and became stronger on day 10.Conclusion: Cortisol is associated with DIND following aneurysmal SAH,  probably through its role in keeping the balance between ET1 and NO level. (Med J Indones. 2013;22:161-6. doi: 10.13181/mji.v22i3.585) Keywords: Cortisol dynamics, delayed ischemic neurological deficits, endothelin-1, nitric oxide
The Determinants of COVID-19 Vaccine Acceptance in Sumatra Cindy Sidarta; Andree Kurniawan; Nata P H Lugito; Jeremia Imanuel Siregar; Veli Sungono; Rivaldo Steven Heriyanto; Novia Lauren Sieto; Devina Adella Halim; Claudia Jodhinata; Saraswati Anindita Rizki; Terry Devita Sinaga; Chintya Marcella; Felix Wijovi; Billy Susanto; Elizabeth Marcella; Johan Wibowo; Jonathan Juniard Anurantha; Michelle Imanuelly; Michele Indrawan; Nadia Khoirunnisa Heryadi
Jurnal Kesehatan Masyarakat Nasional Vol 17, No 1 (2022): Volume 17, Issue 1, February 2022
Publisher : Faculty of Public Health Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (515.858 KB) | DOI: 10.21109/kesmas.v17i1.4958

Abstract

In light of the current coronavirus disease 2019 (COVID-19) vaccination programs being implemented worldwide, this study aimed to evaluate the COVID-19 vaccine acceptance survey in Indonesia conducted by the World Health Organization (WHO), the Ministry of Health of the Republic of Indonesia, the National Immunization Technical Advisory Group (NITAG), and the United Nations Children's Fund (UNICEF), published in November 2020. It was found that Sumatra Island having lower COVID-19 vaccine acceptance rates, with Aceh Province displaying the lowest level of vaccine acceptance. Thus, a cross-sectional study was conducted, and a logistic regression analysis was used to identify the factors affecting COVID-19 vaccine acceptance. Out of 368 respondents who participated in the survey, 143 (38.9%) accepted the vaccine, and 225 (61.1%) refused it. Vaccine safety concerns constituted the most reported reason for refusal (43.6%). This study also found that province of residence and basic immunization status were determinants of COVID-19 vaccine acceptance in Sumatra. Concerns regarding vaccine safety might be the reason for the low level of vaccination in Sumatra. Increased education and encouragement from healthcare professionals and regional authority figures can alleviate public concerns and improve vaccine acceptance.
The Relationship Between Sedentary Lifestyle and Body Mass Index Among Junior High School Students at Jayapura Christian School Engelberta Pardamean; Elvira Wonda; Veli Sungono
Medicinus Vol 9, No 3 (2021): October 2021-January 2022
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i3.4936

Abstract

Introduction: As a result of today's technological advancements, many people, including youngsters, are spending more time watching television, playing video games, or using social media on computers or phones. A sedentary lifestyle refers to behaviors like these. Students' activities became passive as a result of studying online at home. As a result, the chance of acquiring more weight and eventually being obese increases. That is the basic issue addressed in the study. The majority of youngsters spend their time on video games, television, or social networking. One of the signs of a sedentary lifestyle is a lack of physical activity. In youngsters, a lack of physical activity might raise the chance of being overweight or obese.Objective: The purpose of this study is to look into the link between a sedentary lifestyle and a high BMI among Jayapura Christian School Junior High School students.Methods: This is a cross-sectional study including Jayapura Christian School Junior High School students. Purposive sampling is a strategy for collecting data. The Adolescent Sedentary Activity Questionnaire (ASAQ) was used to collect data and determine Sedentary Lifestyles. In addition, BMI categories were utilized to determine whether someone was normal, overweight, or obese.Results: The majority of the respondents have an overweight or obese BMI (n=35; 67.3 percent) and a normal BMI (n=17; 32.7 percent), as well as a heavily sedentary lifestyle (n=45; 86.5 percent) and a moderate or light (n=7; 13.5 percent) lifestyle. Using the chi-square statistical test, the results of the two variables analysis, sedentary lifestyle, and body mass index category yielded a p-value of 0.003 and an odds ratio of 17.37 (95 percent CI:2.262–440.1). When compared to students who have a mild or moderate sedentary lifestyle, students with a severe sedentary lifestyle have an odds 17.37 times higher chance of having a BMI above normal. Conclusions: There is a substantial link between a sedentary lifestyle and a BMI over the usual limit among Jayapura Christian School Junior High School students.
The Relationship between AAS (Addiction Admission Scale) and APS (Addiction Potential Scale) with Timely Graduation of UPH Medical Faculty Students Engelberta Pardamean; veli sungono
Medicinus Vol 7, No 6 (2019): June 2019 - September 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i6.2594

Abstract

Background: Addiction influential to neurotransmitter damage in the brain, resulting in physical fatigue and behavioral changes that will affect the length of studies of students. The MMPI-2 questionnaire is an instrument used to assess the Addiction Admission Scale / AAS and Addiction Potential Scale / APS.Objective: This study looks at the relationship between AAS and APS with the timely graduation of students.Methods: The study design of this research was cross-sectional for students of the Faculty of Medicine who were running a co-ass program at the Dharmawangsa Mental Hospital and had carried out the MMPI-2 test. Data analysis was done using Stata IC version 16 using t-test, spearman correlation test, and logistic regression.Results: Of the 81 respondents, 67% of women and 33% of men and students who graduated on time amounted to 79%. T-test results obtained an AAS score in the group that was not on time (mean 2.53 ± 1.37) significantly higher than the group that was on time / study period of 5.5 years (mean 1.27 ± 1.56) with a p value of 0.0035. APS has a significant correlation to AAS with a coefficient value of r of 0.2595 and p value of 0.0201. AAS logistic regression test for the accuracy of graduation has a p value of 0.0067 with an OR value of 1.559 (95% CI 1.09-2.21).Conclusion: There is a significant relationship between AAS on time graduation and there is no significant relationship between APS with on timely graduation.
Correlation Between The Knowledge On Health Effects Of Smoking And Motivation On Smoking Cessation In Ex-Smokers Of Lung Department Patients, Siloam General Hospital, Lippo Village. Clarinda Wong; Brian Lucas; Veli Sungono; Andree Kurniawan; Allen Widysanto
Medicinus Vol 8, No 2 (2020): June 2020 - September 2020
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v8i2.3435

Abstract

Introduction: Data from WHO showed that deaths caused by tobacco reaches approximately ± 6 million deaths annually. There are many information about the danger of smoking which spreading from various sources. The level of  knowledge about the danger of smoking can be associated with motivation to stop smoking. Therefore, motivation toward smoking cessation arises if someone knows the benefits that can be taken, through an adequate knowledge.Aim: To determine the relationship between the level of knowledge on the health effects of  smoking with motivation to stop smoking in ex-smokers of lung department patients at Siloam General Hospital, Lippo Village.Methodology: This is a cross-sectional study, analyzing 138 ex-smokers of Siloam General Hospital’s lung department patients using consecutive sampling techniques.Results: the results showed 73.2% of people have good knowledge about the danger of smoking and 26.8% are not. Then, 58% of people have high motivation to stop smoking and 42% have low motivation. The results of statistical test using Chi Square showed a significant relationship between the level of knowledge and the motivation to quit smoking (OR = 4.293 [95% CI: 1,921-9,594], P<.001). The results of the multivariate logistic regression test showed educational factors (P=0.014), and the frequency of smoking (P=0.007) also influence the motivation to stop smoking.Conclusion : There’s a significant relation between knowledge about the danger of smoking and the motivation to quit smoking.
The Relationship Between Sedentary Lifestyle and Body Mass Index Among Junior High School Students at Jayapura Christian School Engelberta Pardamean; Elvira Wonda; Veli Sungono
Medicinus Vol 9, No 3 (2021): October 2021 - January 2022
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i3.6973

Abstract

Introduction: As a result of today's technology advancements, many people, including youngsters, are spending more time watching television, playing video games, or using social media on computers or phones. Sedentary lifestyle refers to behaviors like these. Students' activities became passive as a result of studying online at home. As a result, the chance of acquiring more weight and eventually being obese increases. That is the basic issue addressed in the study. The majority of youngsters spend their time on video games, television, or social networking. One of the signs of a sedentary lifestyle is a lack of physical activity. In youngsters, a lack of physical activity might raise the chance of being overweight or obese.Objective: The purpose of this study is to look into the link between a sedentary lifestyle and a high BMI among Jayapura Christian School Junior High School students.Methods: This is a cross-sectional study including Jayapura Christian School Junior High School students. Purposive sampling is a strategy for collecting data. The Adolescent Sedentary Activity Questionnaire (ASAQ) was used to collect data and determine Sedentary Lifestyle. In addition, BMI categories were utilized to determine whether someone was normal, overweight, or obese.Results: The majority of the respondents have an overweight or obese BMI (n=35; 67.3 percent) and a normal BMI (n=17; 32.7 percent), as well as a heavy sedentary lifestyle (n=45; 86.5 percent) and a moderate or light (n=7; 13.5 percent) lifestyle. Using the chi-square statistical test, the results of the two variables analysis, sedentary lifestyle and body mass index category, yielded a p-value of 0.003 and an odds ratio of 17.37 (95 percent CI:2.262–440.1). When compared to students who have a mild or moderate sedentary lifestyle, students with a severe sedentary lifestyle have odds 17.37 times higher chance of having a BMI above normal.Conclusions: There is a substantial link between a sedentary lifestyle and a BMI over the usual limit among Jayapura Christian School Junior High School students.