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Journal : Buletin Farmatera

Perioperative Management of Systemic Lupus Erythematosus Patient with Perianal Abscess Complication due to Trauma Huwainan Nisa Nasution; Lita Diah Rahmawati
Buletin Farmatera Vol 6, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i3.7059

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease that can damage organs and cells due to autoantibodies and immune complexes bound to tissue. Infection is a major source of co-morbid in patients with SLE. The infection has been the second major cause of death in SLE, after disease activity itself. Perianal abscess is part of anorectal abscess which can occur in patients that have a risk factor of trauma on the anorectal region. Management of the patient consists of non-operative and operative procedures. In SLE patients that undergo the operative procedure, it is necessary to do perioperative preparation to prevent post-operative complications such as "flare-up" condition due to SLE. Evaluation of medicines and adjustment of glucocorticoid dosage based on the risk of surgery is important in perioperative preparation.
Case Report: Preoperative Hormone Replacement Therapy in Hypocortisol and Hypothyroid Patients with Residual Pituitary Adenoma Tumors Huwainan Nisa Nasution
Buletin Farmatera Vol 6, No 1 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i1.5636

Abstract

Pituitary tumors are benign tumors that occur in the pituitary gland with a presentation of 10% of all intracranial tumors. If the size of the tumor is           > 1 cm, the pituitary tumor is called a macroadenoma, the large size will have a mass effect so that there is an emphasis on the tumor area and its surroundings. This emphasis will manifest in hyposecretion of the hormones produced in the pituitary. We report a case of  57-year-old male with complaints of decreased vision since 3.5 months. The patient had previously been diagnosed with a pituitary tumor 6 years ago and had surgery. After diagnostic steps, the patient is diagnosed with a residual pituitary adenoma tumor with hypocortisol and hypothyroidism. Hormone replacement therapy was performed by administering methilprednisolone tablets 16 mg-0-8 mg and levothyroxine tablets 1 x 50 µg. The patient was planned to undergo an Endoscopic Endonasal Excision Tumor surgery with  125 mg/12 hour preoperative injection of methilprednisolon. The provision of preoperative hormone replacement therapy aims to correct hormonal imbalances that can be an intraoperative complication
Polyclinic Geriatrics, Rumah Sakit Haji Medan, Risk Factors for Isolated Systolic Hypertension in the Elderly Nadianty Az Zahrah; Huwainan Nisa Nasution
Buletin Farmatera Vol 7, No 2 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i2.9740

Abstract

ABSTRACTIntroduction: Hypertension is a manifestation of hemodynamic balance disorders in the cardiovascular system. Isolated systolic hypertension was defined as systolic blood pressure ?140 mmHg and diastolic blood pressure ?90 mmHg. Objective: The purpose of this study was to analyze the effect of family history, obesity, smoking, physical activity and consumption of salt and fat on the incidence of isolated systolic hypertension in the elderly at the Geriatrics Clinic of Haji Hospital Medan. Method: The design of this study was an analytic observasional study with a case control approach using a questionnaire from patients at the Geriatrics Polyclinic, Haji Hospital Medan. The sampling technique used was purposive sampling. Results: From 90 samples, it was found that there was an effect of family history (p-value=0,003; OR=3,62; CI 95% = 1,51-8,65), smoking (p-value=0,035; OR=2,47; CI 95% = 1,05-5,76), physical activity (p-value=0,010; OR=3,07; CI 95% = 1,28-7,36), and consumption of salt and fat (p-value=0,033; OR=2,53; CI 95% = 1,07-5,98) on the incidence of isolated systolic hypertension in the elderly and there is no effect of obesity on the incidence of isolated systolic hypertension (p-value=0,827; OR=1,10; CI 95% = 0,46-2,59). The results of multivariate analysis showed that the most dominant variable influencing the incidence of isolated systolic hypertension was family history (p-value = 0,023; Exp ? =0,347). Conclusion: There is an effect of family history, smoking, physical activity, and consumption of salt and fat on the incidence of isolated systolic hypertension in the elderly and there is no influence of obesity with the incidence of isolated systolic hypertension in the elderly. The most dominant variable influencing the incidence of isolated systolic hypertension in the elderly is family history.Keyword : Elderly, Isolated Systolic Hypertension, Risk Factors
Relationship between Frequency of Sugar Sweetened-Beverages (SSB) Consumption and Prediabetes: Aim For Screening Prediabetes Among Medical Students Huwainan Nisa Nasution; Eka Febriyanti; Des Suryani
Buletin Farmatera Vol 7, No 1 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i1.9439

Abstract

Sugar sweetened-beverages (SSB) is not only found in soft drinks, fruit juice drinks, or energy drinks, but also various drinks that are currently "trending" such as boba drinks with various flavors, coffee or milk coffee, even tea or milk tea with various flavors. The lifestyle of consuming drinks that are high in sugar will lead to a tendency to several diseases such as prediabetes, diabetes mellitus (DM), metabolic syndrome and cardiovascular disease. Prevention and screening of prediabetes and DM at a young age in Indonesia must be increased, especially in high-risk groups because most of the initial conditions of the disease are asymptomatic. The aim of this study is to analyze the association between frequency of sugar sweetened-beverages (SSB) consumption and prediabetes in medical students. This study was an observational analytic study with cross sectional design conducted at Medical Faculty Universitas Muhammadiyah Sumatera Utara. The subjects of this study was 70 subjects. Examination of frequency of SSB consumption was carried out with a validated questionnaire and food frequency questionnaire (FFQ) of nutrient intake for the past 24 hours. There is no significant relationship between gender, family history of DM, smoking history, physical activity and hypertension with prediabetes. However, there is a significant relationship between obesity and prediabetes with p value 0,010. Meanwhile, the relationship between frequency of SSB consumption and prediabetes showed with p 0.05. There is no significant relationship between frequency of SSB consumption and prediabetes, but there is significant relationship between obesity and prediabetes.