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All Journal JURNAL LPPM BIDANG SAINS DAN TEKNOLOGI INDONESIAN JOURNAL OF PHARMACY Indonesian Journal of Chemistry
Antonius R.B. Ola
Department Of Chemistry, Faculty Of Science And Engineering, Universitas Nusa Cendana, Jl. Adisucipto, Penfui-Kupang 85118, NTT, Indonesia
Chemical Engineering, Chemistry & Bioengineering Chemistry Education Medicine & Pharmacology

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Journal : Indonesian Journal of Chemistry

 1 
C-15 ACETOGENINS FROM THE MARINE ALGA Chondria Antonius R.B. Ola; Bruce F. Bowden
Indonesian Journal of Chemistry Vol 8, No 3 (2008)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1460.121 KB) | DOI: 10.22146/ijc.21603

Abstract

(-) Z-Pinnatifidenyne, a novel C-15 acetogenin has been isolated along with the known compound (+)-3Z,6R,7R-obtusenyne and (+) (3Z)-laurenyne from the Australian red alga Chondria armata. The structures of the compounds were elucidated based on spectral data analysis including 2D NMR spectroscopic experiment.
Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi Nigrospora oryzae Antonius Rolling Basa Ola; Titus Lapailaka; Hermania Em Wogo; Julinda Bendalina Dengga Henuk; Agnes Simamora; Lince Mukkun; Peter Proksch; Chong Dat Pham
Indonesian Journal of Chemistry Vol 21, No 4 (2021)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.63129

Abstract

Mangrove forest has a distinctive habitat adapting with marine and terrestrial environment. Chemical investigation of the extract from mangrove endophytic fungi Nigrospora oryzae had resulted in the isolation of sterigmatocystin (1) and pestalopyrone (2). The structure of sterigmatocystin (1) and pestalopyrone (2) were elucidated using mass, UV and NMR spectrometers together with the comparison with the literature data. The study also showed that sterigmatocystin displayed moderate cytotoxicity but it could be further developed as antiviral and antibacterial agent based on the SAR information reported from its analogue and derivatives.
Co-Authors Agnes Simamora Bibiana Dho Tawo Bruce F. Bowden Chong Dat Pham Ermelinda D Meye Grace Debbie Kandou Hermania Em Wogo Jimmy Posangi Julinda Bendalina Dengga Henuk Lince Mukkun Peter Proksch Robert A. Bara Sismindari . Titus Lapailaka Zullies Ikawati