Lobredia Zarasade
Department Of Plastic Reconstruction And Aesthetic Surgery

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Hambatan Kolonisasi Methicillin Resistant Staphylococcus Aereus oleh Ekstrak Kulit Delima pada Luka Bakar Derajat-2 pada Tikus (INHIBITION OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS BACTERIA COLONIZATION ON SECOND DEGREE BURN WOUND IN WISTAR RAT BY US Iswinarno Doso Saputro; Lobredia Zarasade; Revita Widya Prasanti
Jurnal Veteriner Vol 17 No 3 (2016)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Bacterial of Methicillin Resistant Staphylococcus Aureus (MRSA) is a pathogen that plays an importantrole as a nosocomial pathogen. The bacteria can cause outbreaks of nosocomial infection which is becomeserious problems in the management of burns patients because many strains have changed intomultiresistant bacteria to several classes of antibiotics. Treatment of MRSA bacterial infection in burnsis still a problem because its cost is relatively expensive and there is an increased trend of the bacteriaresistance. Therefore, alternatives are needed to deal with these problems. One of the alternatives is byusing topical pomegranate peel extract . This study was aimed to compare the topical administration ofpomegranate peel extract with mupirocin and to evaluate the combination effect of pomegranate peelextract with mupirocin against bacterial colonization of MRSA on the burn wound rat skin. Second degreeof burn was made by placing a nail with length 2 cm and width 2 cm. Before it used, the nail was boiled inboiling water for 10 seconds. Isolates of MRSA bacteria were inoculated on burn wound in male rats strainWistar. The rats were divided into three groups, each group was treated six hours after bacterial inoculation.The first group was given mupirocin on the burn wound; the second group was given topical pomegranatepeel extract, and the third group received a combination of mupirocin with pomegranate peel extracttopically. Swab culture was taken on the third and fifth day post-treatment. The specimen was sent to theMicrobiology Laboratory for microbiological examination to evaluate the efficacy of pomegranate peel extract in inhibiting bacterial colonization of MRSA. Topical pomegranate fruit peel extract significantlyinhibited MRSA bacterial colonization on the rat’s burn wound{p sig.(2-tailed),0,045, P < 0,05). Nosignificant result was found on bacterial count in topical pomegranate fruit peel extract administationcompared to topical mupirocin administration or in combination between topical pomegranate andmupirocin. Topical pomegranate fruit peel extract has antibacterial effect, eventhough it is not moreeffective compared to mupirocin administration or combination between the pomegranate and mupirocin.
Elevated Serum Transaminase (SGOT/SGPT) and Sepsis in Burn Patients in a Tertiary Hospital, Surabaya, Indonesia Iswinarno Doso Saputro; Lobredia Zarasade; Rifqi Kurniawan
Folia Medica Indonesiana Vol. 58 No. 2 (2022): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (766.638 KB) | DOI: 10.20473/fmi.v58i2.32865

Abstract

Highlights: There is no correlation between the increase of SGOT and sepsis. Correlation between the increase of SGPT and sepsis was significant founded.   Abstract: Burns trigger hypermetabolic stress reactions that cause inflammatory responses. When there is a sustained or increased hypermetabolic reaction, the inflammatory response can be life-threatening, such as sepsis, and significantly impact hepatic metabolic function. After burns, varying degrees of liver injury are usually associated with burn severity. This study determined the correlation between elevated serum transaminases (SGOT/ SGPT) and sepsis in burn patients at a tertiary hospital of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January 1, 2018, to December 31, 2020. This was a descriptive-analytic study with a retrospective cohort design. The data in this study included the demography of burn patients, causes of burns, inhalation trauma, burn severity, increased serum transaminase (SGOT/SGPT), mortality, and sepsis. This study found that the correlation between elevated serum transaminases (SGOT/SGPT) and sepsis was determined using the Spearman-Rho Rank statistical test. Burn patients with sepsis in the hospital were dominated by males (65.2%) and mostly aged 26-55 years (69.6%). The flame was found to be the highest cause of burns (80.4%), burn area above 20% (91.3%), the highest level of severity was major burn (91.3%), and no inhalation trauma (54.3%). In this study, there was an increase in SGOT of 69.6% and SGPT of 78.3%, with a mortality rate of 39.1%, with average inpatient days of 24 days. The correlation test between elevated serum transaminase (SGOT) and sepsis showed an insignificant relationship (p = 0.065, p> 0.05) with a correlation coefficient of 0.200. In contrast, the correlation between elevated serum transaminase (SGPT) and sepsis was significant (p=0.006, p<0.05) with a correlation coefficient of 0.296.
CORELATION OF PARENTS’ PROFILES OF CHILDREN WITH LATE CLEFT REPAIR IN SURABAYA CLEFT LIP AND PALATE CENTRE (JANUARY 2015–DECEMBER 2017) Laras Puspita Ningrum; Iswinarno Doso Saputro; Lobredia Zarasade
Jurnal Rekonstruksi dan Estetik Vol. 5 No. 1 (2020): Jurnal Rekonstruksi dan Estetik, June 2020
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (811.976 KB) | DOI: 10.20473/jre.v5i1.24319

Abstract

Highlights: Economic factors and insufficient information about cleft palate treatment was the primary cause of delayed repairs,except for Parents' education levels. The essential responsibility of primary care physicians is to provide education on treatment stages to minimize delays. Abstract: Introduction:  Optimal time of Cleft palate repair is during the 10 to 12 month of  age.  In  this  time  produce  far  natural  results  in  terms  of  speech  because  it enabled  the  maturation  of  scar  tissue  postoperatively.  The  soft  palate  must function  properly before the  patient  starts learning  to  talk,  otherwise  speech disorders such as persistent rhinolalia aperta might arise. In pediatric patients, the role of parents is very important on adherence to therapy. Methods: This is a cross-sectional study. The first study group was parents of patients who had surgical repair before two years old and the second group was the parents  of  patients  who  had  repair  after  two  years  old.  We  compared  age, monthly income, education level, number of children, and residential distance from Surabaya of the two groups. Results:  The  data  of  this  study  were  obtained  from  the  medical  records  of patients with cleft lip surgery at CLP Center Surabaya in 2015th-2017th with total  of  358  patients,  172  were  female  and  186  were  male.  52  patients  with delayed cleft palate surgery. Patients’ parents in both groups were mostly 31- 40 years old, were high school graduated, has one child, earned less than 1.5 million rupiah a month, and lived less than 100 kms from Surabaya. From the statistical  results,  parent’s  income  has  the  strongest  correlation  with  the patient’s age in cleft palate surgery (-2.7). A negative coefficient means that the less parent’s income, the more patient likely had delayed cleft palate surgery. While other factors found weak and very weak correlations. Conclusions:The  results  form  patient's  parents'  interview,  concluded  that besides economic factors, the lack of information cleft palate treatment is the key  factors  that contributed to  the  delay  of  cleft  palate  repair.  The education level  does  not  affect  the  delay  in  cleft  palate  surgery,  because  even  in  high educated parents, sometimes they don’t understand the stages of cleft lip and palate  treatment.  This  study  emphasized  the  necessity  to  educate  about  the stages of surgery by primary care physicians, to minimize delays.
QUANTITATIVE MEASUREMENT OF BILATERAL CHEILORRHAPHY: A RETROSPECTIVE STUDY Lobredia Zarasade; Pratidina Wulandari
Jurnal Rekonstruksi dan Estetik Vol. 5 No. 1 (2020): Jurnal Rekonstruksi dan Estetik, June 2020
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (789.047 KB) | DOI: 10.20473/jre.v5i1.24324

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Highlights: There were no significant differences in anthropometric measurements across various groups indicating consistent results in these facial parameters. Bilateral cheilorrhaphy using the Djohansjah technique at the Surabaya CLP Center achieved satisfactory symmetry of the lips, nose, and philtrum, with consistent anthropometric measurements in preoperative cleft conditions. Abstract: Introduction: Bilateral cheilorraphy has higher complexity compared to unilateral cheilorraphy. Anthropometric measurements provide nasolabial identification of the surgery result objectively. This study aims to assess the outcome of bilateral cheilorrhaphy with the Djohansjah technique at Surabaya CLP Center. Methods: 26 patients underwent bilateral cheilorrhaphy from January 1 to December 31, 2018, at the Surabaya CLP Center. Anthropometric measurements were performed on control photos one-year post-surgery with the GIMP application (GNU Image Manipulation Software) version 2.10.12 to measure the cupid’s bow width ratio, hemilabial length ratio, nasal width ratio, and philtrum ridge length ratio. A statistical analysis was performed using Independent Sample t-Tes and Mann-Whitney Test. Results: An anthropometric size difference test based on preoperative condition was performed. No significant difference of the cupid’s bow width ratio, hemilabial length ratio, nasal width ratio, and philtrum ridge length ratio between the group of identical cleft lip and unidentical cleft lip with p > 0.05 was found. Likewise, there was no difference between the identical cleft alveolar and unidentical cleft alveolar, as well as the group with or without cleft palate. Conclusions: Symmetry of lips, nose, and philtrum was achieved with bilateral cheilorrhaphy with the Djohansjah technique at the Surabaya CLP Center and there was no significant difference in cupid's bow width ratio, hemilabial length ratio, nasal width ratio, and philtrum ridge length ratio on preoperative cleft condition.
UMBILICAL RECONSTRUCTION WITH DOUBLE OPPOSING SEMILUNAR FLAP, AN APPEALING RESULTS: A CASE SERIES Arif Rahmat Muharram; Agus Santoso Budi; Lobredia Zarasade
Jurnal Rekonstruksi dan Estetik Vol. 3 No. 1 (2018): Jurnal Rekonstruksi dan Estetik, June 2018
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1008.015 KB) | DOI: 10.20473/jre.v3i1.24367

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Highlights: A double opposing semilunar flap has good result for umbilicus reconstruction. A double opposing semilunar ensures a natural appearance and avoids visible scarring while maintaining appropriate depth and size. Abstract: Introduction: Umbilical loss is not a common problem encountered in plastic surgery routine cases. The absence of umbilicus will cause significant effect in total aesthetic appearance of the abdomen, thus making it an essential part of anatomy landmark. Congenital defect, oncologic and abdominoplasty complication are the most often causes, and tremendous psychological trauma will cause patient to seek help. Case Illustration: There are many proposed technique for such reconstruction, based on original scar or wound and final expected shape, of course with their advantages and disadvantages. We used a double opposing semilunar flap for our cases. Along with its technical detail, we will present three cases comprises of the defect after omphalocele scar removal, umbilical endometriosis excision and postcentral abdominal tumor excision. Reports will be presented with preoperative and postoperative result. Discussion: This technique avoids the appearance of scarring and secondary stenosis by hiding the circular scar incision and maintaining its position in the middle of the new form. Conclusion: The reconstruction technique of the umbilicus presented for the anatomical units, provides a very natural look, and generates slight excess of skin on the upper part over time and giving a more graceful appearance. 
SEVERE CONSTRICTED HEAD – AN EXTREME FORM OF CROUZON SYNDROME POSING CHALLENGING FRONTO-ORBITAL ADVANCEMENT: A CASE SERIES REPORTS Ciptomurti Lupitasari; Lobredia Zarasade; Magda Rosalina Hutagalung
Jurnal Rekonstruksi dan Estetik Vol. 4 No. 2 (2019): Jurnal Rekonstruksi dan Estetik, December 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3292.254 KB) | DOI: 10.20473/jre.v4i2.28222

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Highlights: Severe Constricted Head in Crouzon Syndrome. Complex surgical interventions to address severe craniofacial abnormalities in Crouzon syndrome. Abstract: Introduction: Constricted head or cloverleaf deformity in Crouzon syndrome is a severe form of the syndrome involving trilobed coronal and lambdoid synostosis. Crouzon syndrome with acanthosis nigricans is distinct from the classic Crouzon syndrome, characterized by thick and dark skin in body folds. The major problems resulting from constricted head are related to craniostenosis, orbitostenosis developing from abnormalities of the skull base associated with progressive rise in intracranial and intraorbital pressures which could progress to hydrocephalus and cerebellar herniation. Case Illustration: Two cases with severe Crouzon syndrome were reported. The first was a five month old girl associated with acanthosis nigricans and the other was a sixteen month old boy, both whose phenotypic expressions were at the extreme severe end of the disease spectrum. On examination there  was serious corneal exposure, visual loss, severely narrow head, midface hypoplasia, and beaked nose. CT scan showed typical cloverleaf skull, expanded middle cranial fossa, foreshortened anterior and posterior fossae and honeycomb appearance in the occiput involving  pansutural  synostosis and extensive copper beaten deformity from the high intracranial pressure . Both were complicated with hydrocephalus requiring ventricul operitoneal shunt. Discussion: This required an arduous effort in releasing the brain from the multiply punctured calvaria, avoiding excessive dural tear and bleeding and ultimately preserving the brain. Excessive bleeding was also caused by the raised ICP. Both patients are planned to undergo occipital expansion three months later. Conclusion: Severely constricted head in Crouzon syndrome is an extreme manifestation and late stage of the syndrome which not only will result in irreversible complication but will require meticulous surgical technique.
PALATE FRACTURE PROFILE IN PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY OF DR. SOETOMO GENERAL ACADEMIC HOSPITAL: JANUARY 2012- DECEMBER 2017 Priscilla Valentine N.; Agus Santoso Budi; Lobredia Zarasade
Jurnal Rekonstruksi dan Estetik Vol. 4 No. 1 (2019): Jurnal Rekonstruksi dan Estetik, June 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (289.679 KB) | DOI: 10.20473/jre.v4i1.29216

Abstract

Highlights: The demographic data of patients with palate fractures is young adult men aged 19-30 years, the most common of palatal fracture type is parasagittal type, and causes of trauma being traffic accidents. The use of transmolar wiring and plating, occlusion was achieved well. Abstract: Introduction: Palatal fractures are often associated with  maxillofacial fractures and Le Fort fractures. The diagnosis and management of palatal fractures in the midface area is a challenge for a plastic surgeon in restoring function and aesthetics. With the results of this study, it is expected to be a database of maxillofacial fractures treated at SMF Reconstructive Plastic Surgery and Aesthetic Dr. Soetomo General Academic Hospital, Surabaya and gave the ability to make a fast and precise diagnosis for time and technical maxillofacial fractures. Methods: This study uses medical record data for all patients diagnosed with palatal fractures in Dr. Soetomo General Academic Hospital, Surabaya during January 2012 to December 2017. The variables studied were demographic data including sex, age, mechanism of occurrence of accidents, types of fractures, management, complications that occur and length of treatment. Discussion: There were 82 patients with palatal fractures, with traffic accidents being the most common cause of palate fracture (n=61) followed by workplace accidents and households in second place (12 and 9%). Most sufferers were men (68%), women (14%) with the highest age range of men aged 19-30 years who were followed by ages 31-45. The most were parasagittal fractures (56%), then Sagittal (15%), paraalveolar (9%), alveolar (1%), comminutive (1%). no fractures with anterior and posterolateral alveolar types, posterolateral type or transverse type  fractures. Hospitalization period with plating (12 days), transmolar wiring (10.6 days), and conservative (13.8 days). Conclusions: In this study assessed the experience in the reconstruction and aesthetic plastic surgery department of Dr. Soetomo General Academic Hospital regarding palatal fractures and accompanying demographic data. The type of fracture that occurs is also related to the management performed. Incomplete medical records caused problems in this study.