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All Journal Health and Medical Journal Nommensen Journal of Medicine Jurnal Kedokteran Ibnu Nafis Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara
Ervina Julien Sitanggang
Fakultas Kedokteran Universitas HKBP Nommensen
Humanities Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Korelasi Lingkar Pinggang dengan Kadar Gula Darah Puasa, Kadar Trigliserida, dan Tekanan Darah pada Mahasiswa Fakultas Kedokteran Universitas HKBP Nommensen Ervina Julien Sitanggang
Health and Medical Journal Vol 3, No 2 (2021): HEME July 2021
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (554.62 KB) | DOI: 10.33854/heme.v3i2.583

Abstract

Introduction: Cardiovascular disease is the number one cause of death globally with an incidence of adolescents and young adults in Indonesia as many as 153.705 cases. Central obesity is associated with the risk of cardiovascular disease due to increase in fasting blood glucose levels, cholesterol and triglyceride levels, and blood pressure. Aims: to determine the correlation between waist circumference and fasting blood glucose levels, triglyceride levels, and blood pressure in young adults. Method: This analytic study with a cross-sectional approach involved 53 young adult subjects (18-25 years old). Waist circumference is measured using a tape measure. Blood sugar and triglyceride levels were measured using Cobas® 6000 analyzer machine from blood samples of subjects after fasting for 8-12 hours. Blood pressure data are obtained by measurement using aneroid sphygmomanometer. Results: In this study, the mean waist circumference of the research subjects was 77,4 cm. No correlation was found between waist circumference and fasting blood sugar levels (p = 0,159). However, a positive correlation was found between waist circumference and triglyceride levels (p = 0,008; r = 0,332), between waist circumference and systolic blood pressure (p = 0,049; r = 0,230), and between waist circumference and diastolic blood pressure (p = 0,017; r = 0,293). Conclusion: waist circumference is positively correlated with triglyceride levels and blood pressure, but does not correlate with fasting blood sugar levels.
Gambaran Kepatuhan Masyarakat terhadap Protokol Kesehatan dalam Pencegahan COVID-19 di Wilayah Kerja Puskesmas Kabanjahe Tiur Maria Carolina BR Sitanggang; Ervina Julien Sitanggang; Joseph Sibarani; Henny Erina Saurmauli Ompusunggu
Nommensen Journal of Medicine Vol 9 No 1 (2023): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36655/njm.v9i1.1127

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is a disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which causes symptoms of shortness of breath, fever, and cough and is contagious and has infected tens of millions of people worldwide. One of the factors that can lead to the transmission of COVID-19 is the community's non-obedience with the health protocols set by the government, namely 3M.Objective: This study aims to determine the description of community obedience in the working area of the Kabanjahe Public Health Center to health protocols in preventing COVID-19.Methods: This study is a descriptive study with a cross-sectional design. There are 162 respondents who were selected by simple random sampling technique. The research sample was from the population in the working area of the Kabanjahe Public Health Center who were willing to be interviewed. Data were taken using a questionnaire.Results: The results showed that the majority of people in the working area of the Kabanjahe Public Health Center always wash their hands with soap and running water for 40-60 seconds (40,7%) and always use alcohol-based antiseptic liquid (handsanitizer) for at least 20-30 seconds if there is no running water (35,2%), always avoid touching eyes, nose and mouth with unclean hands (50,6%). Always use a mask if you have to leave the house (74,7%) and always use a mask by covering the nose and mouth until the chin reaches (69,8%). Always maintain a minimum distance of 1 meter from other people when outside the house (48,8%) and always avoid crowded places and crowds (55,6%), always take a shower and change clothes after traveling (61,7%), always exercising regularly for at least 30 minutes a day (43,8%), and always getting enough rest for at least 7 hours (67,9%).Conclusion: The majority of the people in the working area of the Kabanjahe Health Center are carrying out health protocols in preventing COVID-19.
Persepsi Alumni terhadap Pencapaian Kurikulum Infeksi Tropis Fakultas Kedokteran Universitas HKBP Nommensen Ristarin Zaluchu; Ervina Julien Sitanggang
Nommensen Journal of Medicine Vol 9 No 1 (2023): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36655/njm.v9i1.1202

Abstract

ABSTRACTS Background: The perceived competence of newly graduated doctors who had undergone clinical practice in their first year could give insight into curriculum accomplishment. Objective: This study aimed to understand alums' perceptions of their performance in tropical infection cases. Methods: Alums who have finished their internship and have been practicing as doctors for less than a year were respondents to this study. We purposefully selected eight respondents based on gender, workplace, and work location. We conducted in-depth interviews by phone. The interview was recorded, and the conversation was transcribed verbatim. Thematic analysis is carried out on transcription by coding and categories. Results: The interview results obtained two significant themes: the perception of competence related to tropical medicine cases and the perception of curriculum implementation. Cases and types of skills influenced perceptions of competence. Respondents perceived curriculum implementation as insufficient and influenced by case exposure, learning methods, and the national final exam. Conclusion: Providing varied cases, improving feedback from clinical supervisors, and initiating early clinical experience are necessary to improve tropical infection competencies. Keywords: perception, medical student, tropical infection ABSTRAK Latar belakang: Persepsi kompetensi alumni yang baru bekerja dapat memberikan informasi mengenai capaian kurikulum. Tujuan: Penelitian ini bertujuan mendapatkan gambaran mengenai persepsi alumni terhadap kompetensinya dalam menghadapi kasus infeksi tropis. Metode: Alumni yang sudah selesai menjalani internship dan telah berpraktek sebagai dokter kurang dari setahun menjadi responden dalam penelitian ini. Terdapat delapan responden yang dipilih dengan teknik purposive sampling, berdasarkan jenis kelamin, tempat kerja, dan lokasi kerja. Pengumpulan data dilakukan dengan wawancara mendalam menggunakan panggilan telepon. Hasil wawancara direkam dan ditranskripsi secara verbatim.Analisis tematik dilakukan terhadap transkripsi dengan cara membuat koding dan kategori. Hasil: Hasil wawancara didapatkan dua tema besar yaitu persepsi kompetensi terkait kasus infeksi tropis dan persepsi mengenai implementasi kurikulum. Kasus dan jenis ketrampilan mempengaruhi persepsi mengenai kompetensi. Responden mempersepsikan implementasi kurikulum infeksi tropis masih kurang mencukupi. Persepsi ini dipengaruhi oleh paparan kasus, metode belajar, dan ujian kompetensi dokter. Kesimpulan: Perbaikan metode pengajaran, memperbanyak kasus, serta umpan balik dari supervisor perlu untuk meningkatkan performa kompetensi kedokteran tropis. Kata Kunci: persepsi; mahasiswa kedokteran; infeksi tropis
Gambaran Profil Hematologi Rutin Pasien TB Paru Sebelum dan Sesudah Pengobatan dengan Obat Antituberkulosis Ervina Julien Sitanggang; Jenny Ria Sihombing
Nommensen Journal of Medicine Vol 9 No 1 (2023): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36655/njm.v9i1.1263

Abstract

Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (M.tb) which often attacks the lung parenchyma and can also attack other organs. Changes can be found in the hematological profile of TB patients both at the time of diagnosis and after treatment. Objective: This study was conducted to obtain routine hematological profiles of pulmonary TB patients before and after treatment with anti-tuberculosis drugs for 3 months, 4 months, and 5 months. Methods: This study was an observational descriptive study. The population in this study was pulmonary TB patients at Martha Friska Hospital and Hermina Medan Hospital for the period October 2021-August 2022. The samples in this study were taken from medical record data of all pulmonary TB patients at Martha Friska Hospital and Hermina Medan Hospital for the period of October 2021-August 2022 (total sampling). Results: In this study, 39 research subjects were obtained, age range of 15-79 years. Before treatment, the majority of patients had anemia (76.92%), leukocytosis (61.54%), normal platelets (66.67%), and elevated ESR (53.85%). After 3 months of treatment, anemia was experienced by 30%, leukocytosis by 0%, normal platelets by 80%, and elevated ESR by 20% of patients. After 4 months of treatment, anemia was experienced by 52.17%, leukocytosis by 4.35%, normal platelets by 65.22%, and elevated ESR by 4.35% of patients. After 5 months of treatment, anemia was experienced by 50%, leukocytosis by 0%, platelets normal by 83.33%, and elevated ESR by 0% of patients. Conclusion: The majority of patients develop anemia, leukocytosis, and elevated ESR before treatment with antituberculosis drugs. There was a decrease in the proportion of patients who developed anemia, leukocytosis, and an elevated ESR after treatment with antituberculosis drugs for 3 months, 4 months, and 5 months.
PERBEDAAN KADAR IFN-γ MIKROENKAPSULASI SEL PUNCA MESENKIMAL COATED DAN NON-COATED: DIFFERENCES IN IFN-γ LEVELS IN COATED and NON-COATED MESENCHYMAL STEM CELL MICROENCAPSULATION Maria Manuella Sibarani; Ervina Julien Sitanggang; Dina Octafrida Marpaung; Christine Verawaty Sibuea
Jurnal Kedokteran Ibnu Nafis Vol. 13 No. 1 (2024): Juni 2024
Publisher : Fakultas Kedokteran Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/jkin.v13i1.610

Abstract

Sampai saat ini multi-drug resistant tuberculosis (MDR-TB) masih menjadi masalah kesehatan global. Fokus utama pengobatan MDR-TB bergantung pada kombinasi antibiotik sebagai terapi penyembuhan bakteriologis yang dapat menyebabkan beberapa efek samping yang merugikan. Penelitian menggunakan sel punca mesenkimal mulai dikembangkan sebagai bentuk terapi baru. Sel punca mesenkimal berfungsi sebagai imunomodulator dan mampu menyekresikan berbagai jenis sitokin, salah satunya IFN-γ. Pada MDR-TB, IFN-γ dapat meningkatkan respons imun seluler untuk mengaktifkan makrofag sebagai penghancur mikroba. Penelitian ini bertujuan untuk mengetahui perbedaan kadar IFN-γ pada medium kultur antara mikroenkapsulasi sel punca mesenkimal yang disalut (coated) dan tidak disalut (non-coated) lisat konsentrat trombosit sebagai studi preliminari terapi seluler MDR-TB. Penelitian ini merupakan penelitian analitik-observasional. Kadar IFN-γ diukur menggunakan spektrofotometer dengan panjang gelombang 450nm. Data yang didapat kemudian dianalisis menggunakan uji Mann-Whitney. Dari hasil penelitian diperoleh sekresi IFN-γ pada kelompok non-coated pada hari ke-2, ke-7, ke-14, dan ke-21 masing-masing sebanyak 0,018 pg/mL, 0,0616 pg/mL, 2,2735 pg/mL, dan 2,2735 pg/mL, sedangkan pada kelompok coated diperoleh data pada hari ke-2, ke-7, ke-14, dan ke-21 masing-masing sebanyak 0 pg/mL, 0 pg/mL, 0,0512 pg/mL, dan 1,7165 pg/mL. Hasil uji Mann-Whitney menunjukkan bahwa tidak terdapat perbedaan kadar IFN-γ pada medium kultur mikroenkapsulasi sel punca mesenkimal coated dan non- coated.
KADAR INTERFERON GAMMA (IFN-γ) MIKROENKAPSULASI MSC-CD34+ DENGAN COATING: STUDI PRELIMINARI TERAPI SELULER MDR-TB Karina Mutiarani Halawa; Ervina Julien Sitanggang; Runggu Napitupulu; Christine Verawaty Sibuea
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 23 No. 2 (2024): Juli 2024
Publisher : Fakultas Kedokteran Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/ibnusina.v23i2.617

Abstract

Multidrug Resistant Tuberculosis (MDR-TB) merupakan kondisi di mana pasien tuberkulosis resistan terhadap minimal dua jenis obat anti tuberkulosis. Pasien MDR-TB sering mengalami efek samping sehingga terapi alternatif perlu dipikirkan. Mesenchymal stem cell (MSC) dan sel punca hematopoietik CD34+ dianggap sebagai alternatif potensial. MSC memiliki sifat imunomodulator, sedangkan CD34+ meningkatkan angiogenesis. Interferon gamma (IFN-γ) merupakan sitokin proinflamasi yang berperan dalam regulasi imunitas tubuh. Penggunaan coating dengan lisat konsentrat trombosit dan mikroenkapsulasi dapat meningkatkan efektivitas terapi. Penelitian ini bertujuan mengetahui rerata kadar IFN-γ pada medium kultur mikroenkapsulasi MSC dan CD34+ dengan coating lisat trombosit. Penelitian ini merupakan penelitian deskriptif observasional. Sampel MSC dan CD34+ yang digunakan masing-masing berasal dari tali pusat dan darah asal tali pusat bayi baru lahir. Kadar IFN-γ diukur menggunakan spektrofotometer dengan panjang gelombang 450nm. Hasil penelitian menunjukkan kadar IFN-γ yang disekresikan pada hari ke-2 berjumlah 0,0597 pg/mL, mengalami penurunan pada hari ke-7 dan hari ke-14, kemudian meningkat pada hari ke-21 sebanyak 2,7337 pg/mL.
Co-Authors Christine Verawaty Sibuea Dina Octafrida Marpaung Henny Erina Saurmauli Ompusunggu Jenny Ria Sihombing Joseph Sibarani Karina Mutiarani Halawa Maria Manuella Sibarani Ristarin Paskarina Zaluchu Runggu Napitupulu Tiur Maria Carolina BR Sitanggang