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Andrini Ariesti
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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PERBANDINGAN TEKANAN INTRAOKULAR LATIHAN BENCHPRESS DAN BICEPS MASS ROUTINE POLA PROGRESSIVE OVERLOAD Dian Eka Saputra; Ardizal Rahman; Andrini Ariesti
HUMAN CARE JOURNAL Vol 5, No 2 (2020): Human Care Journal Special Edition
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i2.787

Abstract

Weight training as an isometric exercise can increase intraocular pressure (IOP) during exercise. Several mechanism theories are proposed in analyzing IOP elevation in weight training. Increased intra-abdominal pressure increases intracranial pressure thereby increasing IOP. Another theory is the Valsalva maneuver which results in an increase in intrathoracic venous pressure that is transmitted to the veins leading to the ocular so that IOP increases. IOP elevations over a period of time are at risk of causing glaucoma and blindness.Method: This study’s sample consisted of 62 students who were given biceps mass routine and benchpress training with 5 sets of progressive overload patterns. IOP values were measured before training, between sets and 30 minutes after rest using a non-contact tonometry.Result: There was a statistically significant correlation between the increase in IOP values between before exercise with the fifth set in the right eye lying position exercise (10.323mmHg) and the left eye (11.419mmHg) to the increase in the IOP value before exercise with the fifth set in the sitting position of the right eye ( 6,581mmHg) and left eye (7,435mmHg).Conclusion: IOP values increase during weight training at both positions of the progressive overload pattern. The greater the training load the greater the IOP value. The lying down position gives the effect of increasing the greater IOP value. 
HUBUNGAN LAMA PAPARAN INHALASI ORGANICSOLVENT TERHADAP PENURUNAN PENGLIHATAN WARNA DAN SENSITIVITAS KONTRAS husnaini husnaini; Getry Sukmawati; Andrini Ariesti
HUMAN CARE JOURNAL Vol 5, No 3 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i3.782

Abstract

Chronic inhalation of organic solvents causes retinal toxicity such as decreased color vision and contrast sensitivity because organic solvents cause damage to photoreceptor function, changes in cortical or retinal neurotransmitter systems such as glutamate, dopamine and acetylcholine and changes in function in parvo, magno and coniocellular cells. Method: The sample of this study consisted of 45 gas station operators who were divided into 3 groups, namely those who worked 1 year-5 years, 5 years-10 years and >10 years. All subjects underwent quantitative color vision examination by calculating the value of the color confusion index (CCI) using Fansworth D15. Contrast sensitivity examination is by determining the log contrast sensitivity value using the Pelli-Robson test. Results: CCI values> 1.00 and log contrast sensitivity values <1.65 were found in officers who worked for >10 years by 12 subjects (80%). Statistically there is a significant relationship between the duration of work with the decrease in color vision and contrast sensitivity (P Value 0,000). Conclusion: There is a significant relationship between the duration of exposure to organic solvents with a decrease in color vision and contrast sensitivity in operator officers who work >10 years.
THE EFFECT OF ORAL VITAMIN D ON TUMOR NECROSIS FACTOR-? EXPRESSION IN TRABECULAR MESHWORK OF WISTAR GLAUCOMA MODEL: Oral Presentation - Experimental Study - Resident RIKHA ERINA; Andrini Ariesti; Hendriati
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/vrszrr85

Abstract

Introduction & ObjectivesElevated intraocular pressure (IOP) is a risk factor for the development and progression of glaucomathat can induces inflammation in the trabecular meshwork through the production of proinflammatorycytokines such as TNF-?. Inflammation induce mechanical stress and changes in theextracellular matrix in the trabecular meshwork, resulting in hypertonicity and resistance toaqueous humor outflow. Vitamin D can modulate cytokine production by suppressing TH1 cellexpression and inducing TH2 cell expression. The production of pro-inflammatory cytokines can besuppressed by the presence of vitamin D. MethodsAn experimental study of 30 wistar glaucoma model were divided into 3 groups, non treatmentgroup ( A and B) and the oral vitamin D (1200 IU/kg/day) group (C) for 14 days. TNF-? expressionsin trabecular meshwork were measured by immunohistochemical staining. Group A was measuredon day 3, while group B and C were measured on day 14. The differences between the three groupswere analyzed statistically using one way ANOVA test. Significantly different if the p<0.05. ResultsThe mean expression of TNF- ? in the trabecular meshwork of wistar glaucoma model in group A, B,and C was 22,2 ± 2,51%, 39,1 ± 3.98%, 34.2 ± 3,19 % respectively. There was significantlydifference in TNF-? expressions between the three groups (p<0.001). ConclusionVitamin D per oral can decrease TNF-? expression in the trabecular meshwork of wistar glaucomamodel on day 14 . Studies in wistar and humans are still needed to assess the effect of vitamin D onothers pro-inflammatory cytokines in glaucoma.
Co-Authors Ardizal Rahman Dian Eka Saputra Getry Sukmawati Hendriati husnaini husnaini RIKHA ERINA